Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Pygopus"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 5, Pp 1745-1752 (2020)
Several techniques have been developed to study specific gene function in loss-of-function situations. In Drosophila melanogaster, RNAi and the generation of mutant clones are widely used. However, both techniques have the limitation that there is a
Externí odkaz:
https://doaj.org/article/4bbbac6c29924ad186beff11bb8fa358
Autor:
Lorenzo Bazzani, David Buechel, Tomas Valenta, Vida Vafaizadeh, Natalia Rubinstein, Claudio Cantù, Meera Saxena, Konrad Basler, Gerhard Christofori, Ravi Kiran Reddy Kalathur, George Hausmann
Publikováno v:
Oncogene
Canonical Wnt/β-catenin signaling is an established regulator of cellular state and its critical contributions to tumor initiation, malignant tumor progression and metastasis formation have been demonstrated in various cancer types. Here, we investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84daaaead4af88da612ea6dc415d977a
http://europepmc.org/articles/PMC8553620
http://europepmc.org/articles/PMC8553620
Autor:
Lu Zheng, Jia Li, Xinhan Lei, Wanwan Li, Jianing Shi, Tong Tang, Shuai Zhang, Lei Zhang, Wenjun Jia, Jintao Qian, Yue Sun
Publikováno v:
Biology Direct, Vol 16, Iss 1, Pp 1-10 (2021)
Biology Direct
Biology Direct
Background Growing evidence has demonstrated that long non-coding RNAs (lncRNAs) can function as modulators in the development of triple-negative breast cancer (TNBC). However, the function of lncRNA small nucleolar RNA host gene 8 (SNHG8) in TNBC re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0547966df61a3b7a7ca0dd0ac0fc9325
https://doaj.org/article/4588354391c241fcbaaa2e4b1a981c82
https://doaj.org/article/4588354391c241fcbaaa2e4b1a981c82
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 309-321 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Cullin-RING ligases (CRLs) recognize and interact with substrates for ubiquitination and degradation, and can be targeted for disease treatment when the abnormal expression of substrates involves pathologic processes. Phosphorylation, either of subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27b7f488f3a53677836e1b8e5b2722d
https://doi.org/10.1016/j.apsb.2020.09.007
https://doi.org/10.1016/j.apsb.2020.09.007
Akademický článek
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Autor:
George Madani
Publikováno v:
Australian Zoologist. 41:102-106
The Western Hooded Scaly-foot Pygopus nigriceps is a widespread pygopod concomitant with the sandy arid zone of inland and western Australia. The limited suitable habitat available and inaccessibility of north western New South Wales means that the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab149d547954fd9857b750cca1b235da
https://doi.org/10.7882/az.2020.017
https://doi.org/10.7882/az.2020.017
Autor:
Nami Sugiyama, Venkatesh Kancherla, Melanie Neutzner, Salvatore Piscuoglio, Claudio Cantù, Gerhard Christofori, Konrad Basler, Jonas Fischer, Ernesta Fagiani, Caner Ercan, Meera Saxena, Mairene Coto-Llerena, Ravi Kiran Reddy Kalathur, Natalia Rubinstein, Andrea Vettiger
Publikováno v:
Cancer Research. 80:3631-3648
Pygopus 2 (Pygo2) is a coactivator of Wnt/β-catenin signaling that can bind bi- or trimethylated lysine 4 of histone-3 (H3K4me2/3) and participate in chromatin reading and writing. It remains unknown whether the Pygo2–H3K4me2/3 association has a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ecf12e2620fa60566726e4fa567fd0b
https://doi.org/10.1158/0008-5472.can-19-2910
https://doi.org/10.1158/0008-5472.can-19-2910
Autor:
Wuzhou Yuan, Jian Zhuang, Yao Wen, Yu Chen, Xiongwei Fan, Jimei Chen, Zhigang Jiang, Xiushan Wu, Huiming Guo, Yang Lei, Huanlei Huang, Wen Yulin, Yongqing Li, Shuoji Zhu, Yuequn Wang, Ping Zhu
Publikováno v:
Current Molecular Medicine. 20:318-324
Background: Our previous studies have shown that Pygo (Pygopus) in Drosophila plays a critical role in adult heart function that is likely conserved in mammals. However, its role in the differentiation of human umbilical cord mesenchymal stem cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2cc6c0ea20db38669aba334e730375e
https://doi.org/10.2174/1566524019666191017150416
https://doi.org/10.2174/1566524019666191017150416
Autor:
Wright, Kevin J., Tjian, Robert
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2009 Jan 01. 106(1), 55-60.
Externí odkaz:
https://www.jstor.org/stable/40272316
Akademický článek
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