Challenges and progress in the application of physiological models for clinical decision support in cardiovascular medicine

Autor: D R Hose, PV Lawford, I Halliday, D Rafiroiu, A Lungu

Publikováno v: IOP Conference Series: Materials Science and Engineering. 1254:012005

The IUPS Physiome and the European Commission’s Virtual Physiological Human (VPH), funded under the Framework 7 programme, are just two of the major initiatives that have supported the development of physiological models for clinical decision suppo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72391ebe39b0f689719ff470b9b4d9b3
https://doi.org/10.1088/1757-899x/1254/1/012005

Modelled impact of virtual fractional flow reserve in patients undergoing coronary angiography (VIRTU-4).

Autor: Ghobrial M; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Haley H; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Gosling R; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute of In Silico medicine, University of Sheffield, Sheffield, UK.; NIHR Sheffield Biomedical Research Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Taylor DJ; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; Insigneo Institute of In Silico medicine, University of Sheffield, Sheffield, UK., Richardson J; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Morgan K; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Barmby D; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Iqbal J; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Krishnamurthy A; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Singh R; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Conway D; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Hall I; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Adam Z; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Wheeldon N; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Grech ED; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Storey RF; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute of In Silico medicine, University of Sheffield, Sheffield, UK.; NIHR Sheffield Biomedical Research Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Rothman A; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute of In Silico medicine, University of Sheffield, Sheffield, UK.; NIHR Sheffield Biomedical Research Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Payne G; Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust, Doncaster, UK., Tahir MN; Barnsley Hospital NHS Foundation Trust, Barnsley, UK., Smith S; The Rotherham NHS Foundation Trust, Rotherham, UK., Cooke J; Chesterfield Royal Hospital NHS Foundation Trust, Chesterfield, UK., Hunter S; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Cartwright N; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Sadeque S; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Briffa NP; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Al-Mohammad A; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., O'Toole L; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Rogers D; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Lawford PV; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; Insigneo Institute of In Silico medicine, University of Sheffield, Sheffield, UK., Hose DR; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; Insigneo Institute of In Silico medicine, University of Sheffield, Sheffield, UK., Gunn J; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute of In Silico medicine, University of Sheffield, Sheffield, UK.; NIHR Sheffield Biomedical Research Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Morris PD; Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK paul.morris@sheffield.ac.uk.; South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute of In Silico medicine, University of Sheffield, Sheffield, UK.; NIHR Sheffield Biomedical Research Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

Publikováno v: Heart (British Cardiac Society) [Heart] 2024 Jul 25; Vol. 110 (16), pp. 1048-1055. Date of Electronic Publication: 2024 Jul 25.

Wearable technology and the cardiovascular system: the future of patient assessment.

Autor: Williams GJ; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Al-Baraikan A; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Rademakers FE; Faculty of Medicine, Department of Cardiology, KU Leuven, Leuven, Belgium., Ciravegna F; Dipartimento di Informatica, Universitàdi Torino, Turin, Italy., van de Vosse FN; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands., Lawrie A; National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK., Rothman A; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; Academic Directorate of Cardiothoracic Services, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Ashley EA; Department of Medicine, Stanford University, Stanford, CA, US., Wilkins MR; National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK., Lawford PV; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Omholt SW; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway., Wisløff U; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway; School of Human Movement & Nutrition Sciences, University of Queensland, QLD, Australia., Hose DR; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Chico TJA; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK; Academic Directorate of Cardiothoracic Services, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; BHF Data Centre, Health Data Research UK, London, UK., Gunn JP; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK; Academic Directorate of Cardiothoracic Services, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Morris PD; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK; Academic Directorate of Cardiothoracic Services, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK. Electronic address: paul.morris@sheffield.ac.uk.

Publikováno v: The Lancet. Digital health [Lancet Digit Health] 2023 Jul; Vol. 5 (7), pp. e467-e476.

The Complementary Value of Absolute Coronary Flow in the Assessment of Patients with Ischaemic Heart Disease (the COMPAC-Flow Study).

Autor: Aubiniere-Robb L; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom., Gosling R; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Department of Cardiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Taylor DJ; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom., Newman T; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Department of Cardiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Rodney D; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Ian Halliday H; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Lawford PV; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Narracott AJ; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Gunn JP; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Department of Cardiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Morris PD; Mathematical Modelling in Medicine Group, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Department of Cardiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2022 Jul; Vol. 1 (7), pp. 611-616. Date of Electronic Publication: 2022 Jul 04.

The importance of three dimensional coronary artery reconstruction accuracy when computing virtual fractional flow reserve from invasive angiography.

Autor: Solanki R; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK., Gosling R; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK.; Department of Cardiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Rammohan V; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Pederzani G; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Garg P; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK.; Norwich Medical School, University of East Anglia, Norwich, UK., Heppenstall J; Department of Radiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Hose DR; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Lawford PV; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Narracott AJ; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Fenner J; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Gunn JP; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK.; Department of Cardiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK., Morris PD; Department of Infection, Immunity and Cardiovascular Disease, The Medical School, University of Sheffield, Sheffield, UK. paul.morris@sheffield.ac.uk.; Department of Cardiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK. paul.morris@sheffield.ac.uk.; Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, UK. paul.morris@sheffield.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2021 Oct 04; Vol. 11 (1), pp. 19694. Date of Electronic Publication: 2021 Oct 04.