Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Putzer J. Hung"'
Autor:
S. Haihua Chu, Jonathan R. Chabon, Chloe N. Matovina, Janna C. Minehart, Bo-Ruei Chen, Jian Zhang, Vipul Kumar, Yijun Xiong, Elsa Callen, Putzer J. Hung, Zhaohui Feng, Richard P. Koche, X. Shirley Liu, Jayanta Chaudhuri, Andre Nussenzweig, Barry P. Sleckman, Scott A. Armstrong
Publikováno v:
iScience, Vol 23, Iss 3, Pp - (2020)
Summary: Repair of DNA double-stranded breaks (DSBs) during lymphocyte development is essential for V(D)J recombination and forms the basis of immunoglobulin variable region diversity. Understanding of this process in lymphogenesis has historically b
Externí odkaz:
https://doaj.org/article/7b6e87225d7445a5aff36d4d395224c3
Autor:
S. Haihua Chu, X. Shirley Liu, Jayanta Chaudhuri, Putzer J Hung, André Nussenzweig, Jian Zhang, Zhaohui Feng, Richard Koche, Bo-Ruei Chen, Elsa Callen, Yijun Xiong, Janna Minehart, Barry P. Sleckman, Vipul Kumar, Scott A. Armstrong, Chloe N. Matovina, Jonathan Chabon
Publikováno v:
iScience
iScience, Vol 23, Iss 3, Pp-(2020)
iScience, Vol 23, Iss 3, Pp-(2020)
Summary Repair of DNA double-stranded breaks (DSBs) during lymphocyte development is essential for V(D)J recombination and forms the basis of immunoglobulin variable region diversity. Understanding of this process in lymphogenesis has historically be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1c417edfd171b9f5660dc3aa4d39ae
https://pubmed.ncbi.nlm.nih.gov/32169821
https://pubmed.ncbi.nlm.nih.gov/32169821
Autor:
Abigail J Morales, Brian T. Edelson, Putzer J Hung, Jacqueline E. Payton, Boris Calderon, Barry P. Sleckman, Javier A. Carrero, Jared M. Andrews, Richard S. Paules, Anthony T. Tubbs, Cynthia L. Innes
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Macrophages produce genotoxic agents, such as reactive oxygen and nitrogen species, that kill invading pathogens. Here we show that these agents activate the DNA damage response (DDR) kinases ATM and DNA-PKcs through the generation of double stranded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6790182f7bf6e79ab54818b2a9944a7
https://doi.org/10.7554/elife.24655
https://doi.org/10.7554/elife.24655
Autor:
Jacqueline E. Payton, Javier A. Carrero, Anthony T. Tubbs, Abigail J Morales, Barry P. Sleckman, Boris Calderon, Cynthia L. Innes, Putzer J Hung, Jared M. Andrews, Richard S. Paules, Brian T. Edelson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e899dd43f40c935841afd2b96078fa5a
https://doi.org/10.7554/elife.24655.021
https://doi.org/10.7554/elife.24655.021
Autor:
Putzer J Hung, Pedro Colon-Ortiz, Barry P. Sleckman, Rosmy George, Jessica K. Tyler, Bo-Ruei Chen, Caleb Liberman, Andrea L. Bredemeyer, Abigail J Morales
Non-homologous end joining (NHEJ) is a major DNA double-strand break (DSB) repair pathway that functions in all phases of the cell cycle. NHEJ repairs genotoxic and physiological DSBs, such as those generated by ionizing radiation and during V(D)J re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db825bad71709474c33c19a15082359
Autor:
Chloe N. Matovina, Jonathan Chabon, Zhaohui Feng, Putzer J Hung, Jian Zhang, Janna Minehart, Scott A. Armstrong, Barry P. Sleckman, S. Haihua Chu, Jayanta Chaudhuri, Bo-Ruei Chen, Richard Koche, X. Shirley Liu, André Nussenzweig, Elsa Callen-Moreu
Publikováno v:
Blood. 132:511-511
Rearrangement of the immunoglobulin heavy chain locus (IgH) through non-homologous end-joining (NHEJ)-mediated VDJ recombination is a requisite step in normal lymphocyte development. This process is initiated through cleavage of DNA by RAG1/2 recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff0c587fa459fdb00e0755745e51278
https://doi.org/10.1182/blood-2018-99-111952
https://doi.org/10.1182/blood-2018-99-111952
Autor:
Shruthi Deivasigamani, Michael L. Gross, Gaya K. Amarasinghe, Shan Zha, John J.H. Petrini, Barry P. Sleckman, Nima Mosammaparast, Bo-Ruei Chen, Brian J. Lee, Putzer J Hung, David J. Pisapia, Jayanta Chaudhuri, Jessica K. Tyler, Tanya E. Johnson, Britney Johnson, Parmeshwar Amatya, Andrea K. Byrum, Andrea L. Bredemeyer, Issa Hindi, William T. Yewdell, Tanya T. Paull
Publikováno v:
Molecular Cell. 71:332-342.e8
The modulator of retrovirus infection (MRI or CYREN) is a 30-kDa protein with a conserved N-terminal Ku-binding motif (KBM) and a C-terminal XLF-like motif (XLM). We show that MRI is intrinsically disordered and interacts with many DNA damage respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5b0473c9dfd481f941110caf6e21f0
https://doi.org/10.1016/j.molcel.2018.06.018
https://doi.org/10.1016/j.molcel.2018.06.018