Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Putman CB"'
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Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors
Autor: Curzon P, Carol S. Surowy, Dart Mj, Ryther Kb, Cao Yj, Michael J. Buckley, M R Schrimpf, Frost Jm, William H. Bunnelle, Ji Jianquo, Arianna Gelain, Puttfarcken P, Anderson Dj, Meyer, Lucio Toma, Searle X, Putman Cb, Daanen Jf, Daniela Barlocco
Publikováno v: Journal of medicinal chemistry. 50(15)
A series of exceptionally potent agonists at neuronal nicotinic acetylcholine receptors (nAChRs) has been investigated. Several N-(3-pyridinyl) derivatives of bridged bicyclic diamines exhibit double-digit-picomolar binding affinities for the alpha 4
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6772a360b44e591cfd2021bbd0f4a4b6
https://pubmed.ncbi.nlm.nih.gov/17585748
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7
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Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis.
Autor: Todorović V; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA. Viktor.Todorovic@abbvie.com., Su Z; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Putman CB; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Kakavas SJ; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Salte KM; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., McDonald HA; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Wetter JB; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Paulsboe SE; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Sun Q; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Gerstein CE; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Medina L; AbbVie Bioresearch Center, 381 Plantation St., Worcester, MA, 01605, USA., Sielaff B; AbbVie Bioresearch Center, 381 Plantation St., Worcester, MA, 01605, USA., Sadhukhan R; AbbVie Bioresearch Center, 381 Plantation St., Worcester, MA, 01605, USA., Stockmann H; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Richardson PL; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Qiu W; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Argiriadi MA; AbbVie Bioresearch Center, 381 Plantation St., Worcester, MA, 01605, USA., Henry RF; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Herold JM; AbbVie Bioresearch Center, 381 Plantation St., Worcester, MA, 01605, USA., Shotwell JB; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., McGaraughty SP; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Honore P; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Gopalakrishnan SM; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Sun CC; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA., Scott VE; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL, 60064, USA. Victoria.E.Scott@abbvie.com.
Publikováno v: Scientific reports [Sci Rep] 2019 Jun 24; Vol. 9 (1), pp. 9089. Date of Electronic Publication: 2019 Jun 24.
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8
Akademický článek
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.
Autor: Hobson AD; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Judge RA; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Aguirre AL; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Brown BS; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Cui Y; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany., Ding P; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Dominguez E; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., DiGiammarino E; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Egan DA; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Freiberg GM; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Gopalakrishnan SM; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Harris CM; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Honore MP; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Kage KL; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Kapecki NJ; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Ling C; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Ma J; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Mack H; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany., Mamo M; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Maurus S; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany., McRae B; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Moore NS; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Mueller BK; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany., Mueller R; AbbVie Deutschland GmbH & Co. KG , Knollstrasse 50 , 67061 , Ludwigshafen , Germany., Namovic MT; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Patel K; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Pratt SD; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Putman CB; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Queeney KL; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Sarris KK; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Schaffter LM; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Stoll V; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Vasudevan A; AbbVie, Inc. , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States., Wang L; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Wang L; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Wirthl W; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States., Yach K; AbbVie Bioresearch Center , 381 Plantation Street , Worcester , Massachusetts 01605 , United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2018 Dec 27; Vol. 61 (24), pp. 11074-11100. Date of Electronic Publication: 2018 Dec 12.
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9
Akademický článek
Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate.
Autor: Judge RA; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Vasudevan A; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Scott VE; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Simler GH; AbbVie Bioresearch Center, 100 Research Drive, Worcester, MA, 01605, USA., Pratt SD; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Namovic MT; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Putman CB; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Aguirre A; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Stoll VS; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Mamo M; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.; Current address: Novartis Institute for Biomedical Research, 4560 Horton Street, Emeryville, CA, 94608, USA., Swann SI; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.; Current address: Takeda Pharmaceuticals, 10410 Science Center Drive, San Diego, CA, 92121, USA., Cassar SC; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Faltynek CR; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA., Kage KL; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.; Current address: Altor Bioscience, 2810 North Commerce Parkway, Miramar, FL, 33025, USA., Boyce-Rustay JM; AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL, 60064, USA.; Current address: Genentech, 1 DNA Way, South San Francisco, CA, 94080, USA., Hobson AD; AbbVie Bioresearch Center, 100 Research Drive, Worcester, MA, 01605, USA.
Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2018 Mar 16; Vol. 19 (6), pp. 613-621. Date of Electronic Publication: 2018 Jan 30.
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10
Akademický článek
Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors.
Autor: Bunnelle WH; Neuroscience Research, Abbott Laboratories, Department R47W, Building AP9A, Abbott Park, Illinois 60064-6117, USA. william.h.bunnelle@abbott.com, Daanen JF, Ryther KB, Schrimpf MR, Dart MJ, Gelain A, Meyer MD, Frost JM, Anderson DJ, Buckley M, Curzon P, Cao YJ, Puttfarcken P, Searle X, Ji J, Putman CB, Surowy C, Toma L, Barlocco D
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2007 Jul 26; Vol. 50 (15), pp. 3627-44. Date of Electronic Publication: 2007 Jun 22.
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