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The constitutive androstane receptor activator 4-[(4R,6R)-4,6-diphenyl-1,3-dioxan-2-yl]-N,N-dimethylaniline inhibits the gluconeogenic genes PEPCK and G6Pase through the suppression of HNF4α and FOXO1 transcriptional activity.

Autor: Yarushkin, Aa, Kachaylo, Em, Pustylnyak, Vo, Yarushkin, A A, Kachaylo, E M, Pustylnyak, V O

Publikováno v: British Journal of Pharmacology; Apr2013, Vol. 168 Issue 8, p1923-1932, 10p

Smoking-Mediated miR-301a/IRF1 Axis Controlling Immunotherapy Response in Lung Squamous Cell Carcinoma Revealed by Bioinformatic Analysis.

Autor: Perevalova AM; Zelman Institute for the Medicine and Psychology, Novosibirsk State University, Pirogova Street, 1, 630090 Novosibirsk, Russia.; Federal Research Center of Fundamental and Translational Medicine, 630117 Novosibirsk, Russia., Kononchuk VV; Federal Research Center of Fundamental and Translational Medicine, 630117 Novosibirsk, Russia., Kalinina TS; Federal Research Center of Fundamental and Translational Medicine, 630117 Novosibirsk, Russia., Kozlov VV; Federal Research Center of Fundamental and Translational Medicine, 630117 Novosibirsk, Russia.; Novosibirsk Regional Oncology Center, 630108 Novosibirsk, Russia., Gulyaeva LF; Zelman Institute for the Medicine and Psychology, Novosibirsk State University, Pirogova Street, 1, 630090 Novosibirsk, Russia.; Federal Research Center of Fundamental and Translational Medicine, 630117 Novosibirsk, Russia., Pustylnyak VO; Zelman Institute for the Medicine and Psychology, Novosibirsk State University, Pirogova Street, 1, 630090 Novosibirsk, Russia.; Federal Research Center of Fundamental and Translational Medicine, 630117 Novosibirsk, Russia.

Publikováno v: Cancers [Cancers (Basel)] 2024 Jun 13; Vol. 16 (12). Date of Electronic Publication: 2024 Jun 13.

Expression of AhR-regulated miRNAs in non-small cell lung cancer in smokers and never smokers.

Autor: Kalinina TS; Institute of Molecular Biology and Biophysics, Federal Research Center for Fundamental and Translational Medicine, Novosibirsk, Russia., Kononchuk VV; Institute of Molecular Biology and Biophysics, Federal Research Center for Fundamental and Translational Medicine, Novosibirsk, Russia; Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia., Valembakhov IS; Institute of Molecular Biology and Biophysics, Federal Research Center for Fundamental and Translational Medicine, Novosibirsk, Russia., Pustylnyak VO; Institute of Molecular Biology and Biophysics, Federal Research Center for Fundamental and Translational Medicine, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia., Kozlov VV; Novosibirsk Regional Oncological Dispensary, Novosibirsk, Russia., Gulyaeva LF; Institute of Molecular Biology and Biophysics, Federal Research Center for Fundamental and Translational Medicine, Novosibirsk, Russia.

Publikováno v: Biomeditsinskaia khimiia [Biomed Khim] 2024 Feb; Vol. 70 (1), pp. 52-60.

Constitutive Androstane Receptor Agonist Initiates Metabolic Activity Required for Hepatocyte Proliferation.

Autor: Mazin ME; Novosibirsk State University, Novosibirsk, 630090, Russia.; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia., Perevalova AM; Novosibirsk State University, Novosibirsk, 630090, Russia., Yarushkin AA; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia., Pustylnyak YA; Novosibirsk State University, Novosibirsk, 630090, Russia., Rogachev AD; Novosibirsk State University, Novosibirsk, 630090, Russia., Prokopyeva EA; Novosibirsk State University, Novosibirsk, 630090, Russia.; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia., Gulyaeva LF; Novosibirsk State University, Novosibirsk, 630090, Russia.; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia., Pustylnyak VO; Novosibirsk State University, Novosibirsk, 630090, Russia. pustylnyak@post.nsu.ru.; Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, 630117, Russia.

Publikováno v: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2023 Aug; Vol. 88 (8), pp. 1061-1069.