Effect of graphite, graphene oxide, and multi-walled carbon nanotubes on the physicochemical characteristics and biocompatibility of chitosan/hyaluronic acid/hydroxyapatite scaffolds for tissue engineering applications

Autor: Siti Fauziyah Rahman, Muhammad Maulana Ghiffary, Joshua Yoshihiko Tampubolon, Elly Septia Yulianti, Muhammad Hanif Nadhif, Puspita Anggraini Katili, Siti Hanafiah, Azizah Intan Pangesty, Muhammad Artha Jabatsudewa Maras

Publikováno v: Journal of Science: Advanced Materials and Devices, Vol 9, Iss 2, Pp 100719- (2024)

Bone tissue engineering (BTE) is a promising alternative approach to the repair of damaged bone tissue. This study aims to fabricate and characterize scaffolds composed of chitosan (CS), hyaluronic acid (HA), hydroxyapatite (HAp), and a combination o

Externí odkaz: https://doaj.org/article/8bbe9c2bee904a70ae36ee538f03efe2

Optimizing PEEK implant surfaces for improved stability and biocompatibility through sandblasting and the platinum coating approach

Autor: Afrah Faadhila, Mohamad Taufiqurrakhman, Puspita Anggraini Katili, Siti Fauziyah Rahman, Delly Chipta Lestari, Yudan Whulanza

Publikováno v: Frontiers in Mechanical Engineering, Vol 10 (2024)

Polyether–ether–ketone (PEEK) is a commonly employed biomaterial for spinal, cranial, and dental implant applications due to its mechanical properties, bio-stability, and radiolucency, especially when compared to metal alloys. However, its biolog

Externí odkaz: https://doaj.org/article/b0ad72ca5adb49f88420feab21203149

Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes

Autor: Nurul A N Mohd Yusof, Christine L. Mummery, Leon G.J. Tertoolen, Jessica Nebel, Peter Clements, Eric I. Rossman, Umber Saleem, Ana Krotenberg Garcia, Kate Harris, Maria L. H. Vlaming, Karen McGlynn, Godfrey L. Smith, Xiaoping Xu, Puspita A Katili, Tessa de Korte, Francis L. Burton, Berend J. van Meer, Ingra Mannhardt, Arne Hansen, Chris Denning, Anthony Bahinski, Thomas Eschenhagen

Publikováno v: Toxicological Sciences
Toxicological Sciences, 176(1), 103-123. OXFORD UNIV PRESS
Toxicological Sciences, 176(1), 103-123. Oxford University Press

Animal models are 78% accurate in determining whether drugs will alter contractility of the human heart. To evaluate the suitability of human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) for predictive safety pharmacology, we quan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e9cc5a4d7797253c1110ea6d84aca8
http://europepmc.org/articles/PMC7357169

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy

Autor: Daniel J. Gaffney, James G W Smith, Ingra Mannhardt, Lucie Carrier, Philip M. Williams, Diogo Mosqueira, Stephen C Harmer, Arne Hansen, Chris Denning, Katarzyna Lis-Slimak, Thomas Eschenhagen, Maksymilian Prondzynski, Puspita A Katili, Andrew Tinker, Jamie R. Bhagwan, Mustafa Hassan, Elizabeth Scott

Publikováno v: Mosqueira, D, Mannhardt, I, Bhagwan, J R, Lis-Slimak, K, Katili, P, Scott, E, Hassan, M, Prondzynski, M, Harmer, S C, Tinker, A, Smith, J G W, Carrier, L, Williams, P M, Gaffney, D, Eschenhagen, T, Hansen, A & Denning, C 2018, ' CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy ', European Heart Journal, vol. 39, no. 43, pp. 3879-3892 . https://doi.org/10.1093/eurheartj/ehy249
European Heart Journal

Aims: Sarcomeric gene mutations frequently underlie hypertrophic cardiomyopathy (HCM), a prevalent and complex condition leading to left ventricle thickening and heart dysfunction. We evaluated isogenic genome-edited human pluripotent stem cell-cardi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879d44d3021bdd166a6a17af02d9e210
https://ueaeprints.uea.ac.uk/id/eprint/69544/