Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Pushpinder Bawa"'
Autor:
Steven Kregel, Chao Wang, Xin Han, Lanbo Xiao, Ester Fernandez-Salas, Pushpinder Bawa, Brooke L. McCollum, Kari Wilder-Romans, Ingrid J. Apel, Xuhong Cao, Corey Speers, Shaomeng Wang, Arul M. Chinnaiyan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 51, Iss , Pp 100986- (2024)
Externí odkaz:
https://doaj.org/article/0674d02ea8d04ff89154c93f395d96db
Autor:
Andrea B. Alber, Hector A. Marquez, Liang Ma, George Kwong, Bibek R. Thapa, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, Pushpinder Bawa, Feiya Wang, Yongfeng Luo, Laertis Ikonomou, Wei Shi, Darrell N. Kotton
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract While the generation of many lineages from pluripotent stem cells has resulted in basic discoveries and clinical trials, the derivation of tissue-specific mesenchyme via directed differentiation has markedly lagged. The derivation of lung-sp
Externí odkaz:
https://doaj.org/article/679e27bdb9be4dbfbe24f069fd027cd6
Autor:
Konstantinos-Dionysios Alysandratos, Carolina Garcia-de-Alba, Changfu Yao, Patrizia Pessina, Jessie Huang, Carlos Villacorta-Martin, Olivia T. Hix, Kasey Minakin, Claire L. Burgess, Pushpinder Bawa, Aditi Murthy, Bindu Konda, Michael F. Beers, Barry R. Stripp, Carla F. Kim, Darrell N. Kotton
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
Dysfunction of alveolar epithelial type 2 cells (AEC2s), the facultative progenitors of lung alveoli, is implicated in pulmonary disease pathogenesis, highlighting the importance of human in vitro models. However, AEC2-like cells in culture have yet
Externí odkaz:
https://doaj.org/article/f25a0ef19189460ebd6f7a2ad18d270c
Autor:
Rupa Kumari, Urbi Roy, Sagar Desai, Namrata M. Nilavar, Annemarie Van Nieuwenhuijze, Amita Paranjape, Gudapureddy Radha, Pushpinder Bawa, Mrinal Srivastava, Mridula Nambiar, Kithiganahalli Narayanaswamy Balaji, Adrian Liston, Bibha Choudhary, Sathees C. Raghavan
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109390- (2021)
Summary: Recombination activating genes (RAGs), consisting of RAG1 and RAG2, are stringently regulated lymphoid-specific genes, which initiate V(D)J recombination in developing lymphocytes. We report the regulation of RAG1 through a microRNA (miRNA),
Externí odkaz:
https://doaj.org/article/b7f3a2f5cb3d435990167d545422c420
Autor:
Geetha Melangath, Titash Sen, Rakesh Kumar, Pushpinder Bawa, Subha Srinivasan, Usha Vijayraghavan
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188159 (2017)
Budding yeast spliceosomal factors ScSlu7 and ScPrp18 interact and mediate intron 3'ss choice during second step pre-mRNA splicing. The fission yeast genome with abundant multi-intronic transcripts, degenerate splice signals and SR proteins is an apt
Externí odkaz:
https://doaj.org/article/085cb913fff341098df4b1ebf4097e9d
Autor:
Pushpinder Bawa, Sajna Zackaria, Mohit Verma, Saurabh Gupta, R Srivatsan, Bibha Chaudhary, Subhashini Srinivasan
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0122143 (2015)
Recently, large numbers of normal human tissues have been profiled for non-coding RNAs and more than fourteen thousand long intergenic non-coding RNAs (lincRNAs) are found expressed in normal human tissues. The functional roles of these normal lincRN
Externí odkaz:
https://doaj.org/article/e04dda983f754ca6b5d07cdcd79490fd
Autor:
Claire L Burgess, Jessie Huang, Pushpinder Bawa, Konstantinos-Dionysios Alysandratos, Kasey Minakin, Michael P Morley, Apoorva Babu, Carlos Villacorta-Martin, Anne Hinds, Bibek R Thapa, Feiya Wang, Adeline M Matschulat, Edward E Morrisey, Xaralabos Varelas, Darrell N Kotton
Publikováno v:
bioRxiv
In the distal lung, alveolar epithelial type I cells (AT1s) comprise the vast majority of alveolar surface area and are uniquely flattened to allow the diffusion of oxygen into the capillaries. This structure along with a quiescent, terminally differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e8b8485fb4c400a98169e1b1e1b898
https://europepmc.org/articles/PMC9882278/
https://europepmc.org/articles/PMC9882278/
Autor:
Lanbo Xiao, Abhijit Parolia, Yuanyuan Qiao, Pushpinder Bawa, Sanjana Eyunni, Rahul Mannan, Sandra E. Carson, Yu Chang, Xiaoju Wang, Yuping Zhang, Josh N. Vo, Steven Kregel, Stephanie A. Simko, Andrew D. Delekta, Mustapha Jaber, Heng Zheng, Ingrid J. Apel, Lisa McMurry, Fengyun Su, Rui Wang, Sylvia Zelenka-Wang, Sanjita Sasmal, Leena Khare, Subhendu Mukherjee, Chandrasekhar Abbineni, Kiran Aithal, Mital S. Bhakta, Jay Ghurye, Xuhong Cao, Nora M. Navone, Alexey I. Nesvizhskii, Rohit Mehra, Ulka Vaishampayan, Marco Blanchette, Yuzhuo Wang, Susanta Samajdar, Murali Ramachandra, Arul M. Chinnaiyan
Publikováno v:
Nature
The switch/sucrose non-fermentable (SWI/SNF) complex has a crucial role in chromatin remodelling1 and is altered in over 20% of cancers2,3. Here we developed a proteolysis-targeting chimera (PROTAC) degrader of the SWI/SNF ATPase subunits, SMARCA2 an
Autor:
Andrea B. Alber, Hector A. Marquez, Liang Ma, George Kwong, Bibek R. Thapa, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, Pushpinder Bawa, Yongfeng Luo, Laertis Ikonomou, Wei Shi, Darrell N. Kotton
The successful generation of endodermal, ectodermal, and most mesodermal lineages from pluripotent stem cells has resulted in basic discoveries and regenerative medicine clinical trials of cell-based therapies. In contrast, the derivation of tissue-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a494c75076f69d42e279da2ae33afea6
https://doi.org/10.1101/2022.08.12.502651
https://doi.org/10.1101/2022.08.12.502651
Autor:
Ronald F, Siebenaler, Seema, Chugh, Jessica J, Waninger, Vijaya L, Dommeti, Carson, Kenum, Malay, Mody, Anudeeta, Gautam, Nidhi, Patel, Alec, Chu, Pushpinder, Bawa, Jennifer, Hon, Richard D, Smith, Heather, Carlson, Xuhong, Cao, John J G, Tesmer, Sunita, Shankar, Arul M, Chinnaiyan
Publikováno v:
PNAS nexus. 1(3)
Activating mutations in RAS GTPases drive nearly 30% of all human cancers. Our prior work described an essential role for Argonaute 2 (AGO2), of the RNA-induced silencing complex, in mutant