Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices

Autor: Pushparajah, DS, Plant, KE, Plant, NJ, Ioannides, C

The current studies investigate whether synergistic or antagonistic interactions in the upregulation of CYP1 activity occur in binary mixtures of polycyclic aromatic hydrocarbons (PAHs) involving benzo[a]pyrene and five other structurally diverse PAH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::b10c97bb8113c6a087abd9ac3637d430
https://eprints.whiterose.ac.uk/118393/1/PAHS-Interactions-ET-R.pdf

Giving Voice to Clinical Study Participants: Development and Deployment of Sequential Patient Experience Surveys for Global Clinical Studies.

Autor: Manning E; UCB Pharma, 8010 Arco Corporate Drive, Raleigh, NC, 27617, USA. Elizabeth.Manning@ucb.com., Herndon M; UCB Pharma, 8010 Arco Corporate Drive, Raleigh, NC, 27617, USA., Frye W; UCB Pharma, 8010 Arco Corporate Drive, Raleigh, NC, 27617, USA., Ice TS; Accelerated Enrollment Solutions, Pharmaceutical Product Development, LLC, Wake Forest, NC, USA., Thyssen N; UCB Pharma, Brussels, Belgium., Pushparajah DS; Alexion Pharmaceuticals, Hayes, UK., Yates SL; UCB Pharma, 8010 Arco Corporate Drive, Raleigh, NC, 27617, USA.

Publikováno v: Therapeutic innovation & regulatory science [Ther Innov Regul Sci] 2020 Sep; Vol. 54 (5), pp. 1001-1009. Date of Electronic Publication: 2020 Jan 21.

Value of Developing Plain Language Summaries of Scientific and Clinical Articles: A Survey of Patients and Physicians.

Autor: Pushparajah DS; 1 UCB Pharma, Slough, United Kingdom., Manning E; 2 UCB Pharma, Raleigh, NC, USA., Michels E; 3 UCB Pharma, Brussels, Belgium., Arnaudeau-Bégard C; 3 UCB Pharma, Brussels, Belgium.

Publikováno v: Therapeutic innovation & regulatory science [Ther Innov Regul Sci] 2018 Jul; Vol. 52 (4), pp. 474-481. Date of Electronic Publication: 2017 Nov 15.

Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices.

Autor: Pushparajah DS; Molecular Toxicology Group, Department of Biochemistry, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom., Plant KE; Molecular Toxicology Group, Department of Biochemistry, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom., Plant NJ; Molecular Toxicology Group, Department of Biochemistry, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom., Ioannides C; Molecular Toxicology Group, Department of Biochemistry, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.

Publikováno v: Environmental toxicology [Environ Toxicol] 2017 Mar; Vol. 32 (3), pp. 764-775. Date of Electronic Publication: 2016 Apr 20.

Family planning and pregnancy issues for women with systemic inflammatory diseases: patient and physician perspectives.

Autor: Chakravarty E; Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA., Clowse ME, Pushparajah DS, Mertens S, Gordon C

Publikováno v: BMJ open [BMJ Open] 2014 Feb 05; Vol. 4 (2), pp. e004081. Date of Electronic Publication: 2014 Feb 05.