Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices

Autor: Pushparajah, DS, Plant, KE, Plant, NJ, Ioannides, C

The current studies investigate whether synergistic or antagonistic interactions in the upregulation of CYP1 activity occur in binary mixtures of polycyclic aromatic hydrocarbons (PAHs) involving benzo[a]pyrene and five other structurally diverse PAH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::b10c97bb8113c6a087abd9ac3637d430
https://eprints.whiterose.ac.uk/118393/1/PAHS-Interactions-ET-R.pdf

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Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices.

Autor: Pushparajah DS; Molecular Toxicology Group, Department of Biochemistry, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom., Plant KE; Molecular Toxicology Group, Department of Biochemistry, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom., Plant NJ; Molecular Toxicology Group, Department of Biochemistry, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom., Ioannides C; Molecular Toxicology Group, Department of Biochemistry, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.

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