Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pushpa-Rekha Thimmalapura"'
Publikováno v:
Arthritis & Rheumatism. 58:3884-3891
Renal failure contributes significantly to the morbidity associated with Systemic Lupus Erythematosus (SLE). However, the molecular mechanisms of renal injury and progressive renal failure are complex and not completely understood. Recently, there ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db9d64a85db632c6972e6e22fe903c5
https://doi.org/10.1002/art.24026
https://doi.org/10.1002/art.24026
Autor:
Harini Bagavant, Umesh S. Deshmukh, Yogesh Scindia, Seshagiri Rao Nandula, Pushpa Rekha Thimmalapura
Publikováno v:
Journal of Oral Pathology & Medicine. 38:42-47
Background: Recent studies have demonstrated the expression of Toll-like receptor 3 (TLR3) in salivary glands and epithelial cell lines derived from Sjogren’s syndrome (SS) patients. As viral infections are considered to be a trigger for SS, in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e2334ef337562f5f21bd79fab291f3
https://doi.org/10.1111/j.1600-0714.2008.00700.x
https://doi.org/10.1111/j.1600-0714.2008.00700.x
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 290:E92-E102
Insulin resistance (IR) is associated with an increased risk of cardiovascular diseases. The obese Zucker rat (ZR) is a model of IR that shows markedly increased insulin and triglyceride concentrations without major changes in glucose. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94720fa9d86d2b6312b909e71c697356
https://doi.org/10.1152/ajpendo.00133.2005
https://doi.org/10.1152/ajpendo.00133.2005
Publikováno v:
Biochemical and Biophysical Research Communications. 308:427-432
Leukocyte type 12-lipoxygenase (12-LO) is an enzyme specifically expressed in the beta cells of the pancreas. 12-LO oxidizes fatty acids such as arachidonic acid and linoleic acids to their respective hydroperoxides. Increased concentration of lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b630583ddb3bd6a11fd7434baea85f17
https://doi.org/10.1016/s0006-291x(03)01418-9
https://doi.org/10.1016/s0006-291x(03)01418-9
Autor:
Soghra Fatima, Marpadga A. Reddy, Jerry L. Nadler, Rama Natarajan, Linda Lanting, Pushpa-Rekha Thimmalapura
Publikováno v:
The Journal of biological chemistry. 277(12)
Evidence suggests that the arachidonic acid metabolite of 12-lipoxygenase, 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE), not only mediates the effects of angiotensin II (AngII), but also has direct effects on hypertrophy and matrix protein product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bff113facee37436c72639ca98378c
https://pubmed.ncbi.nlm.nih.gov/11786549
https://pubmed.ncbi.nlm.nih.gov/11786549
Autor:
Marcus Jonathan Coffey, Philip H. Chumley, Barbara Coles, Hartmut Kühn, Malcolm John Lewis, Bruce A. Freeman, Mari Ann Nowell, Valerie B. O'Donnell, Pushpa-Rekha Thimmalapura, Rama Natarajan
12/15-Lipoxygenase (LOX) activity is elevated in vascular diseases associated with impaired nitric oxide (⋅NO) bioactivity, such as hypertension and atherosclerosis. In this study, primary porcine monocytes expressing 12/15-LOX, rat A10 smooth musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b8a9c0ac602ab1f04ccc1742b30a2b
https://europepmc.org/articles/PMC35458/
https://europepmc.org/articles/PMC35458/
Autor:
Pushpa-Rekha, Thimmalapura R., Burdsall, Andrea L., Oleksa, Lisa M., Chisolm, Guy M., Driscoll, Donna M.
Publikováno v:
Journal of Biological Chemistry; November 1995, Vol. 270 Issue: 45 p26993-26999, 7p