Výsledky vyhledávání - "Pushpa Khanal"

Akademický článek

Dendritic Spine Initiation in Brain Development, Learning and Diseases and Impact of BAR-Domain Proteins

Publikováno v: Cells, Vol 10, Iss 9, p 2392 (2021)

Dendritic spines are small, bulbous protrusions along neuronal dendrites where most of the excitatory synapses are located. Dendritic spine density in normal human brain increases rapidly before and after birth achieving the highest density around 2�

Externí odkaz: https://doaj.org/article/393b6c8b8b9e4c78a1990cdb5e82bbe2

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Akademický článek

MIM-Deficient Mice Exhibit Anatomical Changes in Dendritic Spines, Cortex Volume and Brain Ventricles, and Functional Changes in Motor Coordination and Learning

Autor: Rimante Minkeviciene, Iryna Hlushchenko, Anaïs Virenque, Lauri Lahti, Pushpa Khanal, Tuomas Rauramaa, Arto Koistinen, Ville Leinonen, Francesco M. Noe, Pirta Hotulainen

Publikováno v: Frontiers in Molecular Neuroscience, Vol 12 (2019)

In this study, we performed a comprehensive behavioral and anatomical analysis of the Missing in Metastasis (Mtss1/MIM) knockout (KO) mouse brain. We also analyzed the expression of MIM in different brain regions at different ages. MIM is an I-BAR co

Externí odkaz: https://doaj.org/article/b9f543824eaf4f0ca1512ea0979c5a92

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Akademický článek

ASD-Associated De Novo Mutations in Five Actin Regulators Show Both Shared and Distinct Defects in Dendritic Spines and Inhibitory Synapses in Cultured Hippocampal Neurons

Autor: Iryna Hlushchenko, Pushpa Khanal, Amr Abouelezz, Ville O. Paavilainen, Pirta Hotulainen

Publikováno v: Frontiers in Cellular Neuroscience, Vol 12 (2018)

Many actin cytoskeleton-regulating proteins control dendritic spine morphology and density, which are cellular features often altered in autism spectrum disorder (ASD). Recent studies using animal models show that autism-related behavior can be rescu

Externí odkaz: https://doaj.org/article/8be07ae5562d4254af428994a59302fd

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Gas7 Is a Novel Dendritic Spine Initiation Factor

Autor: Pushpa Khanal, Zoran Boskovic, Lauri Lahti, Aruna Ghimire, Rimante Minkeviciene, Patricio Opazo, Pirta Hotulainen

Funding Information: This work was funded by Academy of Finland Grant SA 307735 (to P.H.); the Doctoral Programme Brain & Mind, University of Helsinki (P.K.); the United Kingdom Dementia Research Institute partner funders (Medical Research Council, A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f8081d8bf4452ff202c79d07347ad7
https://aaltodoc.aalto.fi/handle/123456789/120822

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