Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Pushkar P. Lele"'
Autor:
Annie H. Lee, Rachit Gupta, Hong Nhi Nguyen, Isabella R. Schmitz, Deborah A. Siegele, Pushkar P. Lele
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Bacterial infections that are difficult to eradicate are often treated by sequentially exposing the bacteria to different antibiotics. Although effective, this approach can give rise to epigenetic or other phenomena that may help some cells
Externí odkaz:
https://doaj.org/article/015a0c4b132f4ce4a0492d11a057d598
Autor:
Jyot D. Antani, Rachit Gupta, Annie H. Lee, Kathy Y. Rhee, Michael D. Manson, Pushkar P. Lele
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
It is unclear how bacterial cells adapt the reversible switching of flagellar motor rotation to environments of different viscosities. Here, Antani et al. show that flagellar mechanosensors allosterically control the motor’s binding affinity for th
Externí odkaz:
https://doaj.org/article/0fd537e0ea6a4785bce616b5c69954c7
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/0bd28798c8644f7cbeff1a8560ef65f6
Autor:
Aditya Katiyar, Jian Zhang, Jyot D. Antani, Yifan Yu, Kelsey L. Scott, Pushkar P. Lele, Cynthia A. Reinhart‐King, Nathan J. Sniadecki, Kyle J. Roux, Richard B. Dickinson, Tanmay P. Lele
Publikováno v:
Advanced Science, Vol 9, Iss 23, Pp n/a-n/a (2022)
Abstract Migrating cells must deform their stiff cell nucleus to move through pores and fibers in tissue. Lamin A/C is known to hinder cell migration by limiting nuclear deformation and passage through confining channels, but its role in nuclear defo
Externí odkaz:
https://doaj.org/article/bf83b99aa12048b0bcbc76d06dbce137
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The evolution of the bacterial flagellum gave rise to motility and repurposing of a signaling network, now termed the chemotaxis network, enabled biasing of cell movements. This made it possible for the bacterium to seek out favorable chemical enviro
Externí odkaz:
https://doaj.org/article/fc34b547c8cd4071b4abb9bfe277d67a
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The stator-complex in the bacterial flagellar motor is responsible for surface-sensing. It remodels in response to perturbations in viscous loads, recruiting additional stator-units as the load increases. Here, we tested a hypothesis that th
Externí odkaz:
https://doaj.org/article/d5b89c12869d4a4882eb491dd6fe1569
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Escherichia coli swarm on semi-solid surfaces with the aid of flagella. It has been hypothesized that swarmer cells overcome the increased viscous drag near surfaces by developing higher flagellar thrust and by promoting surface wetness with the aid
Externí odkaz:
https://doaj.org/article/f8c4e3217cf642c79dc0d3ab38128ce4
Publikováno v:
eLife, Vol 10 (2021)
The canonical chemotaxis network modulates the bias for a particular direction of rotation in the bacterial flagellar motor to help the cell migrate toward favorable chemical environments. How the chemotaxis network in Helicobacter pylori modulates f
Externí odkaz:
https://doaj.org/article/8813e60ee4424148815b0b713d7d6283
Autor:
Annie H. Lee, Kathy Y. Rhee, Rachit Gupta, Jyot D. Antani, Michael D. Manson, Pushkar P. Lele
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications
Nature Communications
Reversible switching of the bacterial flagellar motor between clockwise (CW) and counterclockwise (CCW) rotation is necessary for chemotaxis, which enables cells to swim towards favorable chemical habitats. Increase in the viscous resistance to the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec4f5b21e2a0987ec2913b3eadf7d3e
https://doaj.org/article/0fd537e0ea6a4785bce616b5c69954c7
https://doaj.org/article/0fd537e0ea6a4785bce616b5c69954c7
Autor:
Rachit Gupta, Kathy Y Rhee, Sarah D Beagle, Ravi Chawla, Nicolas Perdomo, Steve W Lockless, Pushkar P Lele
Publikováno v:
PNAS nexus. 1(2)
Indole is a major component of the bacterial exometabolome, and the mechanisms for its wide-ranging effects on bacterial physiology are biomedically significant, although they remain poorly understood. Here, we determined how indole modulates the fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1f4a13dc3d2c39a2a49d2abce55467
https://pubmed.ncbi.nlm.nih.gov/35719892
https://pubmed.ncbi.nlm.nih.gov/35719892