Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pushkar A. Phadke"'
Autor:
Artur Zembowicz, Pushkar A. Phadke
Publikováno v:
Clinics in Laboratory Medicine. 31:345-358
Blue nevi and related lesions are characterized by the proliferation of dermal dendritic melanocytes. Although they share certain common clinical and histologic features, they encompass a spectrum of lesions ranging from benign melanocytic hamartomas
Autor:
Mai P. Hoang, Dinesh Rakheja, Maria Angelica Selim, Long P. Le, Martin C. Mihm, Pushkar A. Phadke, Amy Davis, Payal Kapur
Publikováno v:
American Journal of Surgical Pathology. 35:656-669
The histopathologic interpretation of proliferative nodules (PNs) in congenital melanocytic nevi can present significant challenges as some PNs may exhibit atypical features that make the distinction from melanoma difficult. We compared histologic fe
Autor:
Sitaram Harihar, Kedar S. Vaidya, Pushkar A. Phadke, Graham Casey, Lewis J. Stafford, Danny R. Welch, Daryll B. DeWald, Douglas R. Hurst, David G. Hicks
Publikováno v:
Journal of Biological Chemistry. 283:28354-28360
That metastatic tumor cells grow in selective non-native environments suggests an ability to differentially respond to local microenvironments. BRMS1, like other metastasis suppressors, halts ectopic growth (metastasis) without blocking orthotopic tu
Autor:
Pushkar A. Phadke, Robyn R. Mercer, John F. Harms, Yujiang Jia, Andra R. Frost, Jennifer L. Jewell, Karen M. Bussard, Shakira Nelson, Cynthia Moore, John C. Kappes, Carol V. Gay, Andrea M. Mastro, Danny R. Welch
Publikováno v:
Clinical Cancer Research. 12:1431-1440
Purpose: In vivo studies have focused on the latter stages of the bone metastatic process (osteolysis), whereas little is known about earlier events, e.g., arrival, localization, and initial colonization. Defining these initial steps may potentially
Autor:
Gail L. Matters, Laurence M. Demers, Andrea Manni, Pushkar A. Phadke, Judith S. Bond, Danny R. Welch, Monica M. Richert, Douglas J. DiGirolamo, Sharlene Washington
Publikováno v:
Breast Cancer Research : BCR
Introduction Polyamines affect proliferation, differentiation, migration and apoptosis of cells, indicating their potential as a target for cancer chemotherapy. Ornithine decarboxylase converts ornithine to putrescine and is the rate-limiting step in
Autor:
Artur Zembowicz, Pushkar A. Phadke
Publikováno v:
Archives of pathologylaboratory medicine. 135(3)
Context.—Blue nevi are a subset of melanocytic proliferations containing cells reminiscent of the embryonal neural crest–derived dendritic melanocytic precursors. They are common specimens in a general pathology practice, but some of their rare v
Publikováno v:
The American journal of pathology. 172(3)
Breast cancer metastasis suppressor 1 (BRMS1) inhibits formation of macroscopic lung metastases in breast, ovary, and melanoma xenograft models. Because it is unclear which step(s) of the metastatic cascade are affected by BRMS1, the major aim of thi
Autor:
John C. Kappes, Stephen C. Peiper, Pushkar A. Phadke, Kedar S. Vaidya, Danny R. Welch, Kevin T. Nash, Elizabeth Sztul, Mary Ann Accavitti-Loper, Jean-Marc Navenot, Douglas R. Hurst, Andra R. Frost
Background The KISS1 protein suppresses metastasis of several tumor models without blocking orthotopic tumor growth, but the mechanism remains elusive. For its role in human sexual maturation, KISS1 protein is secreted and processed to kisspeptins, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05a08af5d25f5819b2a128c0efe54e7
https://europepmc.org/articles/PMC1820615/
https://europepmc.org/articles/PMC1820615/
Autor:
Danny R. Welch, Rajeev S. Samant, James E. Hopper, Yi Xie, Alka Mehta, Douglas R. Hurst, Pushkar A. Phadke, William J. Meehan, Mary Ann Accavitti, Lalita A. Shevde, Blake P. Moore
Publikováno v:
Biochemical and biophysical research communications. 348(4)
Breast cancer metastasis suppressor 1 (BRMS1) is a member of the mSin3-HDAC transcription co-repressor complex. However, the proteins associated with BRMS1 have not been fully identified. Yeast two-hybrid screen, immuno-affinity chromatography, and c