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X-ray fluorescence mapping of brain tissue reveals the profound extent of trace element dysregulation in stroke pathophysiology.

Autor: Pushie MJ; Department of Surgery, Division of Neurosurgery, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Sylvain NJ; Department of Surgery, Division of Neurosurgery, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Hou H; Department of Surgery, Division of Neurosurgery, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Pendleton N; Department of Surgery, Division of Neurosurgery, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Wang R; College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Zimmermann L; College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Pally M; College of Arts & Science, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Cayabyab FS; Department of Surgery, Division of Neurosurgery, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Peeling L; Department of Surgery, Division of Neurosurgery, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada., Kelly ME; Department of Surgery, Division of Neurosurgery, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5  Canada.

Publikováno v: Metallomics : integrated biometal science [Metallomics] 2024 Nov 15. Date of Electronic Publication: 2024 Nov 15.

Investigating Cu(I) binding to model peptides of N-terminal Aβ isoforms.

Autor: Strausbaugh Hjelmstad A; Department of Chemistry, Duke University, Durham, NC 27708, USA., Pushie MJ; Department of Surgery, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Ruth K; Department of Chemistry, Duke University, Durham, NC 27708, USA., Escobedo M; Department of Mathematics and Computer Science, Saint Mary's College, Notre Dame, Indiana 46556, USA., Kuter K; Department of Mathematics and Computer Science, Saint Mary's College, Notre Dame, Indiana 46556, USA., Haas KL; Department of Chemistry, Duke University, Durham, NC 27708, USA. Electronic address: kathryn.haas@duke.edu.

Publikováno v: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Apr; Vol. 253, pp. 112480. Date of Electronic Publication: 2024 Jan 09.

Neuronal and Astrocyte Insulin-like Growth Factor-1 Signaling Differentially Modulates Ischemic Stroke Damage.

Autor: Hayes CA; Department of BioMolecular Sciences, University of Mississippi School of Pharmacy, University of Mississippi, University, MS 386671., Morgan NI; Department of BioMolecular Sciences, University of Mississippi School of Pharmacy, University of Mississippi, University, MS 386671., Thomas KC; Department of BioMolecular Sciences, University of Mississippi School of Pharmacy, University of Mississippi, University, MS 386671., Pushie MJ; Department of Surgery, College of Medicine, University of Saskatchewan, SK S7N 5E5 Canada., Vijayasankar A; Department of BioMolecular Sciences, University of Mississippi School of Pharmacy, University of Mississippi, University, MS 386671., Ashmore BG; Department of BioMolecular Sciences, University of Mississippi School of Pharmacy, University of Mississippi, University, MS 386671., Wontor K; Department of Chemistry and Biochemistry, The University of Mississippi, University, Mississippi 38677, United States., De Leon MA; Department of BioMolecular Sciences, University of Mississippi School of Pharmacy, University of Mississippi, University, MS 386671., Ashpole NM; Department of BioMolecular Sciences, University of Mississippi School of Pharmacy, University of Mississippi, University, MS 386671.; Research Institute of Pharmaceutical Sciences, University of Mississippi School of Pharmacy, University of Mississippi, University, MS 38677.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Apr 02. Date of Electronic Publication: 2023 Apr 02.

Alzheimer's Drug PBT2 Interacts with the Amyloid β 1-42 Peptide Differently than Other 8-Hydroxyquinoline Chelating Drugs.

Autor: Summers KL; Molecular and Environmental Sciences Group, Department of Geological Sciences, College of Arts and Science, University of Saskatchewan, 114 Science Place, Saskatoon, SaskatchewanS7N 5E2, Canada.; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, SaskatchewanS7N 5C9, Canada., Roseman G; Department of Chemistry and Biochemistry, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California95064, United States., Schilling KM; Department of Chemistry and Biochemistry, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California95064, United States., Dolgova NV; Molecular and Environmental Sciences Group, Department of Geological Sciences, College of Arts and Science, University of Saskatchewan, 114 Science Place, Saskatoon, SaskatchewanS7N 5E2, Canada., Pushie MJ; Department of Surgery, University of Saskatchewan, 103 Hospital Drive, Saskatoon, SaskatchewanS7N 0W8, Canada., Sokaras D; Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, California94025, United States., Kroll T; Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, California94025, United States., Harris HH; Department of Chemistry, University of Adelaide, Adelaide, SA5005, Australia., Millhauser GL; Department of Chemistry and Biochemistry, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California95064, United States., Pickering IJ; Molecular and Environmental Sciences Group, Department of Geological Sciences, College of Arts and Science, University of Saskatchewan, 114 Science Place, Saskatoon, SaskatchewanS7N 5E2, Canada.; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, SaskatchewanS7N 5C9, Canada., George GN; Molecular and Environmental Sciences Group, Department of Geological Sciences, College of Arts and Science, University of Saskatchewan, 114 Science Place, Saskatoon, SaskatchewanS7N 5E2, Canada.; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, SaskatchewanS7N 5C9, Canada.

Publikováno v: Inorganic chemistry [Inorg Chem] 2022 Sep 19; Vol. 61 (37), pp. 14626-14640. Date of Electronic Publication: 2022 Sep 08.