Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Purushotham Guroji"'
Autor:
Do Yeon Cho, Shaoyan Zhang, Ahmed Lazrak, Daniel Skinner, Harrison M. Thompson, Jessica Grayson, Purushotham Guroji, Saurabh Aggarwal, Zsuzsanna Bebok, Steven M. Rowe, Sadis Matalon, Eric J. Sorscher, Bradford A. Woodworth
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101998- (2021)
Lipopolysaccharide (LPS) serves as the interface between gram-negative bacteria (GNB) and the innate immune response in respiratory epithelial cells (REC). Herein, we describe a novel biological role of LPS that permits GNB to persist in the respirat
Externí odkaz:
https://doaj.org/article/833ac3ac1c0742a7bd95fc923f346f51
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155882 (2016)
The most common mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene leads to deletion of the phenylalanine at position 508 (ΔF508) in the CFTR protein and causes multiple folding and functional defects. Contrary to large-
Externí odkaz:
https://doaj.org/article/948aedcb4f444aac89e9fab9971d9f0b
Publikováno v:
Molecular carcinogenesis. 61(8)
Aberrant activation of multiple complex signaling pathways underlies the pathogenesis of rhabdomyosarcoma (RMS), which remains a cause of mortality in approximately 30% of children with RMS. Bromodomain and extraterminal (BET) domain chromatin remode
Autor:
Bradford A. Woodworth, Steven M. Rowe, Zsuzsanna Bebok, Daniel Skinner, Jessica W. Grayson, Purushotham Guroji, Eric J. Sorscher, Shaoyan Zhang, Do-Yeon Cho, Ahmed Lazrak, Saurabh Aggarwal, Harrison M. Thompson, Sadis Matalon
Publikováno v:
Redox Biology
Redox Biology, Vol 43, Iss, Pp 101998-(2021)
Redox Biology, Vol 43, Iss, Pp 101998-(2021)
Lipopolysaccharide (LPS) serves as the interface between gram-negative bacteria (GNB) and the innate immune response in respiratory epithelial cells (REC). Herein, we describe a novel biological role of LPS that permits GNB to persist in the respirat
5'-Cap‒Dependent Translation as a Potent Therapeutic Target for Lethal Human Squamous Cell Carcinoma
Autor:
Ritesh K. Srivastava, Aadithya Arumugam, Andrzej Slominski, Craig A. Elmets, Suhail Muzaffar, Jasim Khan, Purushotham Guroji, Marina S. Gorbatyuk, Mohammad Athar, M. Shahid Mukhtar
Publikováno v:
J Invest Dermatol
Skin squamous cell carcinomas (SCCs) are a major cause of death in patients who have undergone or will undergo organ transplantation. Moreover, these neoplasms cause significant disease and economic burden and diminish patients' life quality. However
Autor:
Radomir M. Slominski, Mohammad Athar, Robert C. Tuckey, Jörg Reichrath, Tae Kang Kim, Purushotham Guroji, Andrzej Slominski, Anna A. Brożyna, Craig A. Elmets, Zorica Janjetovic, Anton M. Jetten, Rebecca S. Mason, Michal A. Zmijewski
Publikováno v:
Sunlight, Vitamin D and Skin Cancer ISBN: 9783030462260
Adv Exp Med Biol
Adv Exp Med Biol
Nonmelanoma skin cancers including basal and squamous cell carcinomas (SCC and BCC) represent a significant clinical problem due to their relatively high incidence, imposing an economic burden to healthcare systems around the world. It is accepted th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebc1fd574e431c69a27190bc92a9fbb
https://doi.org/10.1007/978-3-030-46227-7_13
https://doi.org/10.1007/978-3-030-46227-7_13
Autor:
Purushotham, Guroji, Padma, Yerukala1, Nabiha, Yusuf2, Venkata Raju, R.1 rrvenkataraju@yahoo.com
Publikováno v:
3 Biotech. 10/1/2016, Vol. 6 Issue 2, p1-11. 11p.
Autor:
Tae Kang Kim, Shariq Qayyum, Zorica Janjetovic, Mohammad Athar, Andrzej Slominski, Purushotham Guroji
Publikováno v:
Journal of Investigative Dermatology. 140:S86
Publikováno v:
The FASEB Journal. 30:201-213
Synonymous mutations, such as I507-ATC→ATT, in deletion of Phe508 in cystic fibrosis transmembrane conductance regulator (ΔF508 CFTR), the most frequent disease-associated mutant of CFTR, may affect protein biogenesis, structure, and function and
Autor:
Nabiha Yusuf, Purushotham Guroji, Amanda H. DeBrot, Padma Manapragada, Israr Ahmad, Craig A. Elmets, Santosh K. Katiyar
Publikováno v:
Experimental dermatology. 26(11)
The CDKN2A locus encodes for tumor suppressor genes p16INK4a and p14Arf which are frequently inactivated in human skin tumors. The purpose of this study was to determine the relationship between loss of INK4a/Arf activity and inflammation in the deve