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Akademický článek

Divergent transcriptomic signatures from putative mesenchymal stimuli in glioblastoma cells.

Autor: Hart WS; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, 22903, USA., Myers PJ; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, 22903, USA., Purow BW; Department of Neurology, University of Virginia, Charlottesville, VA, 22903, USA., Lazzara MJ; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, 22903, USA. mlazzara@virginia.edu.; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 22903, USA. mlazzara@virginia.edu.

Publikováno v: Cancer gene therapy [Cancer Gene Ther] 2024 Jun; Vol. 31 (6), pp. 851-860. Date of Electronic Publication: 2024 Feb 09.

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Akademický článek

Understanding current experimental models of glioblastoma-brain microenvironment interactions.

Autor: Yadav N; Department of Neurology, University of Virginia Comprehensive Cancer Center, University of Virginia Health System, Charlottesville, VA, 22903, USA.; Medical Scientist Training Program, School of Medicine, University of Virginia, Charlottesville, VA, 22908, USA., Purow BW; Department of Neurology, University of Virginia Comprehensive Cancer Center, University of Virginia Health System, Charlottesville, VA, 22903, USA. bwp5g@uvahealth.org.

Publikováno v: Journal of neuro-oncology [J Neurooncol] 2024 Jan; Vol. 166 (2), pp. 213-229. Date of Electronic Publication: 2024 Jan 05.

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Akademický článek

The semaphorin 3A/neuropilin-1 pathway promotes clonogenic growth of glioblastoma via activation of TGF-β signaling.

Autor: Jeon HM; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Shin YJ; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea., Lee J; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea.; Graduate School of Health Science & Technology, Samsung Advanced Institute for Health Science & Technology, Sungkyunkwan University, Seoul, South Korea., Chang N; Graduate School of Health Science & Technology, Samsung Advanced Institute for Health Science & Technology, Sungkyunkwan University, Seoul, South Korea., Woo DH; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Lee WJ; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Nguyen D; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Kang W; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea., Cho HJ; Department of Biomedical Convergence Science and Technology, Kyungpook National University, Daegu, South Korea., Yang H; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea., Lee JK; Department of Biomedical Sciences and Department of Anatomy and Cell Biology, Seoul National University, College of Medicine, Seoul, South Korea., Sa JK; Department of Biomedical Sciences, Korea University, College of Medicine, Seoul, South Korea., Lee Y; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea., Kim DG; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea., Purow BW; Department of Neurology, University of Virginia, Charlottesville, Virginia, USA., Yoon Y; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea.; Graduate School of Health Science & Technology, Samsung Advanced Institute for Health Science & Technology, Sungkyunkwan University, Seoul, South Korea., Nam DH; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea.; Graduate School of Health Science & Technology, Samsung Advanced Institute for Health Science & Technology, Sungkyunkwan University, Seoul, South Korea., Lee J; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Publikováno v: JCI insight [JCI Insight] 2023 Nov 08; Vol. 8 (21). Date of Electronic Publication: 2023 Nov 08.

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Akademický článek

Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling.

Autor: Jeon HM; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Kim JY; Divisions of Radiation Cancer Research, Research Center for Radio-Senescence, Korea Institute of Radiological and Medical Sciences, Seoul, Korea., Cho HJ; Department of Biomedical Convergence Science and Technology, Kyungpook National University, Daegu, Korea., Lee WJ; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Nguyen D; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Kim SS; Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea., Oh YT; Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea., Kim HJ; Divisions of Radiation Cancer Research, Research Center for Radio-Senescence, Korea Institute of Radiological and Medical Sciences, Seoul, Korea., Jung CW; Divisions of Radiation Cancer Research, Research Center for Radio-Senescence, Korea Institute of Radiological and Medical Sciences, Seoul, Korea., Pinero G; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Joshi T; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hambardzumyan D; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sakaguchi T; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Hubert CG; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., McIntyre TM; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Fine HA; Department of Neurology, Weill Cornell Medicine, New York, NY, USA., Gladson CL; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Wang B; Department of Medicine, MetroHealth Campus, School of Medicine, Case Western Reserve University, Cleveland, OH, USA., Purow BW; Department of Neurology, UVA Cancer Center, University of Virginia Health System, Charlottesville, VA, USA., Park JB; Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea., Park MJ; Divisions of Radiation Cancer Research, Research Center for Radio-Senescence, Korea Institute of Radiological and Medical Sciences, Seoul, Korea., Nam DH; Institute for Refractory Cancer Research, Samsung Medical Center, Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Department of Neurosurgery Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Lee J; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address: leej7@ccf.org.

Publikováno v: Cancer cell [Cancer Cell] 2023 Aug 14; Vol. 41 (8), pp. 1480-1497.e9. Date of Electronic Publication: 2023 Jul 13.

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Akademický článek

A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment.

Autor: Cornelison RC; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA, 01003, USA.; Department of Biomedical Engineering & Mechanics, Virginia Tech, Blacksburg, VA, 24061, USA., Yuan JX; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 22904, USA., Tate KM; Department of Biomedical Engineering & Mechanics, Virginia Tech, Blacksburg, VA, 24061, USA.; Fralin Biomedical Research Institute, Virginia Tech, Roanoke, VA, 24016, USA., Petrosky A; Department of Biomedical Engineering & Mechanics, Virginia Tech, Blacksburg, VA, 24061, USA., Beeghly GF; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 22904, USA., Bloomfield M; Department of Biological Sciences and Fralin Life Sciences Institute, Virginia Tech, Blacksburg, VA, 24061, USA., Schwager SC; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 22904, USA., Berr AL; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 22904, USA., Stine CA; Department of Biomedical Engineering & Mechanics, Virginia Tech, Blacksburg, VA, 24061, USA.; Fralin Biomedical Research Institute, Virginia Tech, Roanoke, VA, 24016, USA., Cimini D; Department of Biological Sciences and Fralin Life Sciences Institute, Virginia Tech, Blacksburg, VA, 24061, USA., Bafakih FF; University of Virginia School of Medicine, Charlottesville, VA, 22903, USA.; Department of Pathology, University of Virginia, Charlottesville, VA, 22903, USA., Mandell JW; University of Virginia School of Medicine, Charlottesville, VA, 22903, USA.; Department of Pathology, University of Virginia, Charlottesville, VA, 22903, USA., Purow BW; University of Virginia School of Medicine, Charlottesville, VA, 22903, USA.; Department of Neurology, University of Virginia, Charlottesville, VA, 22903, USA., Horton BJ; University of Virginia School of Medicine, Charlottesville, VA, 22903, USA.; Department of Public Health Sciences, University of Virginia, Charlottesville, VA, 22903, USA., Munson JM; Department of Biomedical Engineering & Mechanics, Virginia Tech, Blacksburg, VA, 24061, USA. munsonj@vt.edu.; Fralin Biomedical Research Institute, Virginia Tech, Roanoke, VA, 24016, USA. munsonj@vt.edu.

Publikováno v: NPJ precision oncology [NPJ Precis Oncol] 2022 Jul 29; Vol. 6 (1), pp. 54. Date of Electronic Publication: 2022 Jul 29.

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Akademický článek

Identification of ritanserin analogs that display DGK isoform specificity.

Autor: Granade ME; University of Virginia, School of Medicine, Department of Pharmacology, Charlottesville, VA, United States., Manigat LC; University of Virginia, School of Medicine, Department of Pathology, Charlottesville, VA, United States., Lemke MC; University of Virginia, School of Medicine, Department of Pharmacology, Charlottesville, VA, United States., Purow BW; University of Virginia, Department of Neurology, Division of Neuro-Oncology, Charlottesville, VA, United States. Electronic address: bwp5g@virginia.edu., Harris TE; University of Virginia, School of Medicine, Department of Pharmacology, Charlottesville, VA, United States. Electronic address: teh3c@virginia.edu.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2022 Mar; Vol. 197, pp. 114908. Date of Electronic Publication: 2022 Jan 06.

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