Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Purong Zheng"'
Autor:
Jian Jin, Ziyu Wang, Long Wan, Ou Yingye, Cheng Wenming, Ruwen Lin, Hongzu Li, Zhang Qianli, Xuelu Bei, Weibin Wu, Li Shuo, Xuan Zhang, Huang Weixin, Chunyun Hu, Yao Ma, Jinlong Rao, Jie Yan, Youyou Cai, Ningbin Wu, Wen Xiaoming, Shoujia Liu, Tingting Pan, Gang Liu, Purong Zheng
Publikováno v:
Journal of medicinal chemistry. 61(4)
Salutaxel (3) is a conjugate of docetaxel (7) and a muramyl dipeptide (MDP) analogue. Docetaxel (7) has been recognized as a highly active chemotherapeutic agent against various cancers. MDP and its analogues are powerful potentiators of the antitumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718232f96caab8321f632feb9152fb77
https://pubmed.ncbi.nlm.nih.gov/29357251
https://pubmed.ncbi.nlm.nih.gov/29357251
Autor:
Thulasi Warrier, Carl Nathan, David Little, Selin Somersan Karakaya, Purong Zheng, Xiaoyong Guo, Yao Ma, Yaling Gong, Gang Liu, Maneesh Pingle, Xiuju Jiang, Julia Roberts, Ben Gold
Publikováno v:
European Journal of Medicinal Chemistry. 75:336-353
Tuberculosis remains one of the deadliest infectious diseases, killing 1.4 million people annually and showing a rapid increase in cases resistant to multiple drugs. New antibiotics against tuberculosis are urgently needed. Here we describe the desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34df53b0b0e3941c1ee059eac6b2276
https://doi.org/10.1016/j.ejmech.2014.01.039
https://doi.org/10.1016/j.ejmech.2014.01.039
Autor:
Zhiwei Chen, Xiaofan Lu, Xu Zhang, Gang Liu, Terrence Chi-Kong Lau, Bo-Jian Zheng, Li Liu, Stephen Kwok-Wing Tsui, Purong Zheng, Yuanxi Kang
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:341-351
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are one of the key components of antiretroviral therapy drug regimen against human immunodeficiency virus type 1 (HIV-1) replication. We previously described a newly synthesized small molecule,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af964681c4f6cef0777eeb748e5ae0ef
https://doi.org/10.1128/aac.05537-11
https://doi.org/10.1128/aac.05537-11
Autor:
Zijie Liu, Yan Li, Gang Liu, Hai Xue, Zhiwei Chen, Li Liu, Lin Wang, Purong Zheng, Chunyan Han, Xiaofan Lu, Jinping Hu, Tao Ma
Publikováno v:
Journal of Medicinal Chemistry. 53:1397-1401
We herein report a new compound: 10-chloromethyl-11-demethyl-12-oxo-calanolide A (20, EC(50) = 7.4 nM, SI = 1417), which demonstrates a druggable profile with 32.7% oral bioavailability in rat, tolerated oral single dose toxicity in mice, and especia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0003e0dbd8c58513d65942273d43f0
https://doi.org/10.1021/jm901653e
https://doi.org/10.1021/jm901653e
Autor:
Maneesh Pingle, Purong Zheng, Gang Liu, Ben Gold, Shi-Chao Lu, David Little, Carl Nathan, Xiaoyong Guo, Steven J. Brickner, Thulasi Warrier, Selin Somersan-Karakaya, Julia Roberts
Publikováno v:
Journal of medicinal chemistry. 57(9)
It is urgent to introduce new drugs for tuberculosis to shorten the prolonged course of treatment and control drug-resistant Mycobacterium tuberculosis (Mtb). One strategy toward this goal is to develop antibiotics that eradicate both replicating (R)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec748c2e9cf004c89fd2e740d99df34
https://pubmed.ncbi.nlm.nih.gov/24694175
https://pubmed.ncbi.nlm.nih.gov/24694175
Autor:
Xiaoming Wen, Purong Zheng, Yao Ma, Yingye Ou, Weixin Huang, Shuo Li, Shoujia Liu, Xuan Zhang, Ziyu Wang, Qianli Zhang, Wenming Cheng, Ruwen Lin, Hongzu Li, Youyou Cai, Chunyun Hu, Ningbin Wu, Long Wan, Tingting Pan, Jinlong Rao, Xuelu Bei
Publikováno v:
Journal of Medicinal Chemistry; 2/22/2018, Vol. 61 Issue 4, p1519-1540, 22p