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pro vyhledávání: '"Purnima Pathre"'
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Autor:
Garrett A. Osswald, Michael Brusilovsky, Mario A. Ynga-Durand, Ting Wen, Jeff E. Habel, Marc E. Rothenberg, Purnima Pathre, Netali Ben Baruch-Morgenstern, Pablo J. Abonia, Adina Y. Ballaban, Julie M. Caldwell, Nurit P. Azouz, Yueh-Chiang Hu, John A. Besse, Andrea M. Klingler
Publikováno v:
Sci Transl Med
Eosinophilic esophagitis (EoE) is a chronic, food antigen–driven, inflammatory disease of the esophagus and is associated with impaired barrier function. Evidence is emerging that loss of esophageal expression of the serine peptidase inhibitor, kaz
Publikováno v:
The Journal of Cell Biology
Cadherins and integrins must function in a coordinated manner to effectively mediate the cellular interactions essential for development. We hypothesized that exchange of proteins associated with their cytoplasmic domains may play a role in coordinat
Autor:
Mei Dong, Jin Dong, Lily Li, Luc Van Kaer, Ming Xu, Danyvid Olivares-Villagómez, James M. Wells, Danwen Lou, Jianhua Zhang, Xiaodong Wang, Yunxia Fan, Purnima Pathre
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(26)
Endonuclease G (EndoG) is a nuclear-encoded mitochondrial protein reported to be important for both nuclear DNA fragmentation during apoptosis and mitochondrial DNA replication. To evaluate thein vivofunction of EndoG, we have investigated the effect
Autor:
Guillermo Romero, Simon C. Watkins, Sean Alber, Anna Blumental-Perry, Anna Bielli, Meir Aridor, Kuntala Shome, Charles J. Haney, Purnima Pathre
Publikováno v:
The EMBO journal. 22(16)
The small GTPase Sar1p controls the assembly of the cytosolic COPII coat that mediates export from the endoplasmic reticulum (ER). Here we demonstrate that phospholipase D (PLD) activation is required to support COPII-mediated ER export. PLD activity
Autor:
Theresa Wampler, Jack Lilien, TinChung Leung, Carlos O. Arregui, Ia Kue, Janne Balsamo, Purnima Pathre
Publikováno v:
Journal of neuroscience research. 63(2)
N-cadherin and beta1-integrin adhesion and signaling play important roles in growth cone adhesion and guidance. Each of these adhesion receptor systems is composed of multiprotein complexes, and both adhesion and downstream signaling events are regul