Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Purine Synthesis Inhibition"'
Autor:
Hadas Landesman, Ayelet Erez, Omer Goldman, Sergey Malitsky, Sivan Galai, Alexander Brandis, Tevi Mehlman, Keyur Talsania, S. Eleonore Koehler, Yael Kuperman, Eytan Ruppin, Lisha Qiu Jin Lim, Igor Ulitsky, Angel Porgador, Yongmei Zhao, Roni Oren, Shaul Lerner, Joo Sang Lee, Maxim Itkin, Hila Weiss Tishler, Rotem Katzir, Shiran Rabinovich, Nir Peled, Noa Stettner, Lital Adler, Yuri Kuznetsov, Rom Keshet, Muhammed Iraqi, Tsai-wei Shen, Yarden Ariav
Publikováno v:
Nature Cancer
Nature Cancer, 1(9), 894-908. Nature Publishing Group
Nature Cancer, 1(9), 894-908. Nature Publishing Group
Argininosuccinate synthase (ASS1) downregulation in different tumors has been shown to support cell proliferation and yet, in several common cancer subsets ASS1 expression associates with poor patient prognosis. Here we demonstrate that ASS1 expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193f750c2610f8dd4d6709f2a1e2b1be
Autor:
Alexander Kamb, Dineli Wickramasinghe, Minqing Rong, Astrid Ruefli-Brasse, Tim Carlson, Kim Quon, Jianxia Shi, Jessica Orf, Doreen Sakamoto
Publikováno v:
Journal of Cancer Therapy. :523-534
Methylthioadenosine phosphorylase, (MTAP) is a key enzyme in the adenine and methionine salvage pathways. MTAP is encoded on human chromosome 9p21 in close proximity to the p16INK4a and p14ARF tumor suppressor genes and is frequently co-deleted with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::481498327f9cb3375a3c78b29fb50640
https://doi.org/10.4236/jct.2011.24072
https://doi.org/10.4236/jct.2011.24072
Autor:
N. V. Starshinova, M. N. Filimonova
Publikováno v:
Microbiology. 74:310-313
The biosynthesis of nuclease in Serratia marcescens has been studied under the conditions of purine synthesis inhibition with 2-(p-aminobenzenesulfonamide)-thiazole. The addition of this sulfonamide to S. marcescens at different growth stages is foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6250fd2266a930fc1cbde4254af3b1b7
https://doi.org/10.1007/s11021-005-0068-x
https://doi.org/10.1007/s11021-005-0068-x
Autor:
Marilyn Jansen, Gary K. Smith, David S. Duch, Jacqueline I. Lee, Michael J. Dykstra, Jeremy Stables, Peter Topley, Robert J. Mullin, Vincent C. Knick
Publikováno v:
Biochemical Pharmacology. 47:1067-1078
Clinical responses for anticancer agents are based upon tumor regression. We have investigated the potential of glycineamide ribonucleotide transformylase (GAR TFase) inhibitors to produce regressions in multiple preclinical models of colon carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16620ff373751c7981dc7a5b0c845f8b
https://doi.org/10.1016/0006-2952(94)90419-7
https://doi.org/10.1016/0006-2952(94)90419-7
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