Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Purificación, Muñoz"'
Autor:
Marta Lopez-Cerda, Laura Lorenzo-Sanz, Victoria da Silva-Diz, Sandra Llop, Rosa M. Penin, Josep Oriol Bermejo, Richard de Goeij-de Haas, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Juan Martin-Liberal, Purificación Muñoz
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background Early cutaneous squamous cell carcinomas (cSCCs) generally show epithelial differentiation features and good prognosis, whereas advanced cSCCs present mesenchymal traits associated with tumor relapse, metastasis, and poor survival
Externí odkaz:
https://doaj.org/article/2d2e3cd7ff3f4fedbed353deaa311a0c
Autor:
Laura Lorenzo-Sanz, Marta Lopez-Cerda, Victoria da Silva-Diz, Marta H. Artés, Sandra Llop, Rosa M. Penin, Josep Oriol Bermejo, Eva Gonzalez-Suarez, Manel Esteller, Francesc Viñals, Enrique Espinosa, Marc Oliva, Josep M. Piulats, Juan Martin-Liberal, Purificación Muñoz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Immune checkpoint blockade (ICB) approaches have changed the therapeutic landscape for many tumor types. However, half of cutaneous squamous cell carcinoma (cSCC) patients remain unresponsive or develop resistance. Here, we show that, during
Externí odkaz:
https://doaj.org/article/6c15c4009def405287d24b7b6ae51b70
Autor:
Olga Boix, Marion Martinez, Santiago Vidal, Marta Giménez-Alejandre, Lluís Palenzuela, Laura Lorenzo-Sanz, Laura Quevedo, Olivier Moscoso, Jorge Ruiz-Orera, Pilar Ximénez-Embún, Nikaoly Ciriaco, Paolo Nuciforo, Camille Stephan-Otto Attolini, M. Mar Albà, Javier Muñoz, Tian V. Tian, Ignacio Varela, Ana Vivancos, Santiago Ramón y Cajal, Purificación Muñoz, Carmen Rivas, María Abad
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Small proteins encoded by previously assumed non-coding RNAs can have cell regulatory functions. Here the authors report that TINCR lncRNA encodes pTINCR, a ubiquitin-like protein (UBL) that promotes epithelial differentiation through the SUMOylation
Externí odkaz:
https://doaj.org/article/33af4f773e164ef482636020595123dd
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-24 (2022)
Abstract Immunotherapy has emerged as a promising strategy for boosting antitumoral immunity. Blockade of immune checkpoints (ICs), which regulate the activity of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells has proven clinical benefi
Externí odkaz:
https://doaj.org/article/7d32ca9e6ba94ab49d287602e5776a86
Autor:
Clara Gómez-Aleza, Bastien Nguyen, Guillermo Yoldi, Marina Ciscar, Alexandra Barranco, Enrique Hernández-Jiménez, Marion Maetens, Roberto Salgado, Maria Zafeiroglou, Pasquale Pellegrini, David Venet, Soizic Garaud, Eva M. Trinidad, Sandra Benítez, Peter Vuylsteke, Laura Polastro, Hans Wildiers, Philippe Simon, Geoffrey Lindeman, Denis Larsimont, Gert Van den Eynden, Chloé Velghe, Françoise Rothé, Karen Willard-Gallo, Stefan Michiels, Purificación Muñoz, Thierry Walzer, Lourdes Planelles, Josef Penninger, Hatem A. Azim, Sherene Loi, Martine Piccart, Christos Sotiriou, Eva González-Suárez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Receptor activator of nuclear factor-κB (RANK)/RANK-ligand (RANKL) signaling regulates the tumor-immune crosstalk. Here the authors show that systemic RANKL inhibition promotes CD8 + T cell infiltration in patients with early breast cancer and that
Externí odkaz:
https://doaj.org/article/25343e5b801f4662be448798ebe81a76
Autor:
Jorge Gómez-Miragaya, Marta Palafox, Laia Paré, Guillermo Yoldi, Irene Ferrer, Sergi Vila, Patricia Galván, Pasquale Pellegrini, Hector Pérez-Montoyo, Ana Igea, Purificación Muñoz, Manel Esteller, Angel R. Nebreda, Ander Urruticoechea, Idoia Morilla, Sonia Pernas, Fina Climent, María Teresa Soler-Monso, Ana Petit, Violeta Serra, Aleix Prat, Eva González-Suárez
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1392-1407 (2017)
Taxanes are a mainstay of treatment for breast cancer, but resistance often develops followed by metastatic disease and mortality. Aiming to reveal the mechanisms underlying taxane resistance, we used breast cancer patient-derived orthoxenografts (PD
Externí odkaz:
https://doaj.org/article/4f17da8dcc6a4c1abea0af3c702c89e0
Autor:
Purificación Muñoz, Francesc Viñals, Alberto Villanueva, Salvador Capella-Gutierrez, Eva González-Suárez, Joan Maria Viñals, Ricard Mesia, Josep M. Piulats, Noelia Vilariño, Miren Taberna, Josep Oriol Bermejo, Diana Pérez Sidelnikova, Rosa M. Penin, Luis Palomero, Mattia Bosio, Victoria da Silva-Diz, Laura Lorenzo-Sanz, Juan Navarro-Ventura, Adrià Bernat-Peguera
Supplementary Figures and legend figures Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9433eeab755aae21f9ba85eb1db9013
https://doi.org/10.1158/1078-0432.22478709.v1
https://doi.org/10.1158/1078-0432.22478709.v1
Autor:
Alberto Villanueva, Julián Cerón, Xavier García-del-Muro, Francesc Viñals, Albert Morales, Lourdes Farré, Gabriel Capella, Josep R. Germà, Manel Esteller, Enric Condom, Miguel A. Pujana, Milica Stefanovic, Purificación Muñoz, Victor Moreno, Merce Juliachs, Wilmar Castillo, Carmen Martínez-Fernández, Sara Puertas, David G. Molleví, Àlvaro Aytés, Laura Padullés, Elisabet Guinó, Agnés Figueras, Josefina Mora, María Martínez-Iniesta, Catia Moutinho, Marga Nadal, Clara Muñoz, Francisco J. García-Rodríguez, August Vidal, Josep M. Piulats
Short- and long-term CDDP responses at low (2 mg/kg) and high (5 mg/kg) doses of CDDP were characterized in xenografted tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de0e6f19041ca518d88b8b8936fa9fc
https://doi.org/10.1158/1078-0432.22464726.v1
https://doi.org/10.1158/1078-0432.22464726.v1
Autor:
Alberto Villanueva, Julián Cerón, Xavier García-del-Muro, Francesc Viñals, Albert Morales, Lourdes Farré, Gabriel Capella, Josep R. Germà, Manel Esteller, Enric Condom, Miguel A. Pujana, Milica Stefanovic, Purificación Muñoz, Victor Moreno, Merce Juliachs, Wilmar Castillo, Carmen Martínez-Fernández, Sara Puertas, David G. Molleví, Àlvaro Aytés, Laura Padullés, Elisabet Guinó, Agnés Figueras, Josefina Mora, María Martínez-Iniesta, Catia Moutinho, Marga Nadal, Clara Muñoz, Francisco J. García-Rodríguez, August Vidal, Josep M. Piulats
Impact of some RNAi clones on cisplatin toxicity in Caenorhabditis elegans adults
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070fd406a8c9aa0f058773b3bbc8ba85
https://doi.org/10.1158/1078-0432.22464729
https://doi.org/10.1158/1078-0432.22464729
Autor:
Alberto Villanueva, Julián Cerón, Xavier García-del-Muro, Francesc Viñals, Albert Morales, Lourdes Farré, Gabriel Capella, Josep R. Germà, Manel Esteller, Enric Condom, Miguel A. Pujana, Milica Stefanovic, Purificación Muñoz, Victor Moreno, Merce Juliachs, Wilmar Castillo, Carmen Martínez-Fernández, Sara Puertas, David G. Molleví, Àlvaro Aytés, Laura Padullés, Elisabet Guinó, Agnés Figueras, Josefina Mora, María Martínez-Iniesta, Catia Moutinho, Marga Nadal, Clara Muñoz, Francisco J. García-Rodríguez, August Vidal, Josep M. Piulats
Purpose: To investigate the genetic basis of cisplatin resistance as efficacy of cisplatin-based chemotherapy in the treatment of distinct malignancies is often hampered by intrinsic or acquired drug resistance of tumor cells.Experimental Design: We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ec1c9a029f1738c2f7dbdc80dbe910
https://doi.org/10.1158/1078-0432.c.6525786.v1
https://doi.org/10.1158/1078-0432.c.6525786.v1