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pro vyhledávání: '"Purdie, Mark"'
Akademický článek
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Publikováno v:
In Journal of Molecular Catalysis. A, Chemical 2010 324(1):39-47
Autor:
Erwin Irdam, Christopher J. Welch, Aaron S. Cote, Jean W. Tom, Pierre Boulas, Joel M. Hawkins, Kenneth M. Wells, Charles D. Papageorgiou, David Dermot Patrick Laffan, Margaret M. Faul, Purdie Mark, Rahn McKeown, Scott A. May, Steven J. Wittenberger, Srinivas Tummala, Kevin D. Seibert, Nicholas Murray Thomson, Frederick Hicks, Antonio Christian Ferretti, Paul Frank Fernandez, Keith Horspool, Shailendra Bordawekar, Bing-Shiou Yang
Publikováno v:
Organic Process Research & Development. 21:414-419
The creation of the Enabling Technologies Consortium (ETC) is described. The ETC fosters precompetitive collaborations aimed at the development and evaluation of new enabling technologies for pharmaceutical research and development, with an initial f
Autor:
David R. J. Hose, Robert Osborne, Paul M. Murray, Jeremy N. Harvey, Gareth J. J. Owen-Smith, Purdie Mark, Guy C. Lloyd-Jones, Natalie Fey, Jesús Jover, A. Guy Orpen
Publikováno v:
Jover Modrego, J, Fey, N, Harvey, J N, Lloyd-Jones, G C, Orpen, A G, Owen-Smith, G J J, Murray, P, Hose, DRJ, Osborne, R & Purdie, M 2012, ' Expansion of the ligand knowledge base for chelating P,P-donor ligands (LKB-PP) ', Organometallics, vol. 31, no. 15, pp. 5302-5306 . https://doi.org/10.1021/om300312t
Organometallics
Organometallics
We have expanded the ligand knowledge base for bidentate P,P- and P,N-donor ligands (LKB-PP, Organometallics 2008, 27, 1372-1383) by 208 ligands and introduced an additional steric descriptor (nHe(8)). This expanded knowledge base now captures inform
Autor:
Paul Colbon, Jianliang Xiao, Keith R. Mulholland, Jonathan H. Barnard, Ivan V. Kozhevnikov, Purdie Mark
Publikováno v:
Advanced Synthesis & Catalysis. 354:1395-1400
Aryl alcohols are employed as feedstock for the Heck reaction. Keggin-type heteropolyacids catalyse the selective dehydration of the alcohols to styrenes, which, in one-pot, undergo palladium-catalysed Heck arylation with aryl bromides, affording bro
Autor:
Robert Osborne, Jesús Jover, A. Guy Orpen, David R. J. Hose, Natalie Fey, Purdie Mark, Guy C. Lloyd-Jones, Jeremy N. Harvey, Gareth J. J. Owen-Smith, Paul M. Murray
Publikováno v:
Organometallics. 29:6245-6258
We have expanded the ligand knowledge base for monodentate P-donor ligands (LKB-P, Chem. Eur. J. 2006, 12, 291−302) by 287 ligands and added descriptors derived from computational results on a gold complex [AuClL]. This expansion to 348 ligands cap
Autor:
Paul Siedlecki, Lyn Powell, Simon M. Pointon, Purdie Mark, J. Gair Ford, Withnall Jane, Anne O’Kearney-McMullan, Phil O’Keefe Frances Wood
Publikováno v:
Organic Process Research & Development. 14:1088-1093
In a previous publication (Org. Process Res. Dev. 2010, 14, DOI:10.1021/op100161y) we described the process research and development of a manufacturing route for the potent SRC kinase inhibitor AZD0530. While the route was successfully used to manufa
Autor:
Natalie Fey, Jeremy N. Harvey, Paul M. Murray, A. Guy Orpen, Robert Osborne, Purdie Mark, Guy C. Lloyd-Jones
Publikováno v:
Organometallics. 27:1372-1383
The ligand knowledge base approach has been extended to capture the properties of 108 bidentate P,P- and P,N-donor ligands. This contribution describes the design of the ligand set and a range of DFT-calculated descriptors, capturing ligand propertie
Akademický článek
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