Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Puran Singh Sijwal"'
Autor:
Zeba Rizvi, G Srinivas Reddy, Somesh M Gorde, Priyanka Pundir, Divya Das, Puran Singh Sijwali
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1012045 (2024)
Protein ubiquitination is essential for cellular homeostasis and regulation of several processes, including cell division and genome integrity. Ubiquitin E3 ligases determine substrate specificity for ubiquitination, and Cullin-RING E3 ubiquitin liga
Externí odkaz:
https://doaj.org/article/58f14229da034d4eac73f5355dc5883f
Autor:
Devasahayam Arokia Balaya Rex, Arun H. Patil, Prashant Kumar Modi, Mrudula Kinarulla Kandiyil, Sandeep Kasaragod, Sneha M. Pinto, Nandita Tanneru, Puran Singh Sijwali, Thottethodi Subrahmanya Keshava Prasad
Publikováno v:
ACS Omega, Vol 7, Iss 10, Pp 8246-8257 (2022)
Externí odkaz:
https://doaj.org/article/7e5585d7e73e4282a17c4384c57d003c
Autor:
Renu Sudhakar, Navin Adhikari, Saniya Pamnani, Abhipsa Panda, Manish Bhattacharjee, Zeba Rizvi, Sadaf Shehzad, Dinesh Gupta, Puran Singh Sijwali
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Despite a remarkable improvement in health care and continued drug discovery efforts, malaria control efforts are continuously challenged by the emergence of drug-resistant parasite strains. Given a long and risky development path of new dru
Externí odkaz:
https://doaj.org/article/894974f997fb45c886e4cb2e337a563d
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Simple and efficient transfection methods for genetic manipulation of Plasmodium falciparum are desirable to identify, characterize and validate the genes with therapeutic potential and better understand parasite biology. Among the available
Externí odkaz:
https://doaj.org/article/2ad36a5cb9fe4cf584b58fdab4b364fe
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113220 (2014)
Conventional autophagy is a lysosome-dependent degradation process that has crucial homeostatic and regulatory functions in eukaryotic organisms. As malaria parasites must dispose a number of self and host cellular contents, we investigated if autoph
Externí odkaz:
https://doaj.org/article/0f5e8bd3f9c34235bdf6fe79baa114b0
Autor:
Rajesh Prasad, Atul, Venkata Karunakar Kolla, Jennifer Legac, Neha Singhal, Rahul Navale, Philip J Rosenthal, Puran Singh Sijwali
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73530 (2013)
Among key potential drug target proteolytic systems in the malaria parasite Plasmodium falciparum are falcipains, a family of hemoglobin-degrading cysteine proteases, and the ubiquitin proteasomal system (UPS), which has fundamental importance in cel
Externí odkaz:
https://doaj.org/article/da1542a6f57a4921a7644e2d2876ba79
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51619 (2012)
Papain-like cysteine proteases of malaria parasites degrade haemoglobin in an acidic food vacuole to provide amino acids for intraerythrocytic parasites. These proteases are potential drug targets because their inhibitors block parasite development,
Externí odkaz:
https://doaj.org/article/0d0e7aa79cd6422b95d191c1e9594b0e
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10227 (2010)
The erythrocytic stage development of malaria parasites occurs within the parasitophorous vacuole inside the infected-erythrocytes, and requires transport of several parasite-encoded proteins across the parasitophorous vacuole to several locations, i
Externí odkaz:
https://doaj.org/article/e0ddbed7be474fb4a0d7d782aff3682e
Autor:
Neha Bajwa, Preet Amol Singh, Srishti Naryal, Trisha Sharma, Puran Singh Sijwal, Ashish Baldi
Publikováno v:
Analytical Chemistry Letters. 12:715-729