Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pupu Ge"'
Autor:
Jing Wang, Qiyao Chai, Zehui Lei, Yiru Wang, Jiehua He, Pupu Ge, Zhe Lu, Lihua Qiang, Dongdong Zhao, Shanshan Yu, Changgen Qiu, Yanzhao Zhong, Bing-Xi Li, Lingqiang Zhang, Yu Pang, George Fu Gao, Cui Hua Liu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 8, Pp 1755-1790 (2024)
Abstract Chronic infections, including Mycobacterium tuberculosis (Mtb)-caused tuberculosis (TB), can induce host immune exhaustion. However, the key checkpoint molecules involved in this process and the underlying regulatory mechanisms remain largel
Externí odkaz:
https://doaj.org/article/ae6f6b1e577e473187f3a8bfd0f24742
Autor:
Lihua Qiang, Yong Zhang, Zehui Lei, Zhe Lu, Shasha Tan, Pupu Ge, Qiyao Chai, Mengyuan Zhao, Xinwen Zhang, Bingxi Li, Yu Pang, Lingqiang Zhang, Cui Hua Liu, Jing Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Ferroptosis is an iron-dependent form of cell death whose role in infectious diseases is being elucidated. Here, Qiang et al. show that PtpA, an effector secreted by Mycobacterium tuberculosis, induces ferroptosis by hijacking host arginine methyltra
Externí odkaz:
https://doaj.org/article/405c017846364b8bbadd2726bef8588d
Autor:
Mengyuan Zhao, Yong Zhang, Lihua Qiang, Zhe Lu, Zhuo Zhao, Yesheng Fu, Bo Wu, Qiyao Chai, Pupu Ge, Zehui Lei, Xinwen Zhang, Bingxi Li, Jing Wang, Lingqiang Zhang, Cui Hua Liu
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112655- (2023)
Summary: The regulation of antiviral immunity is crucial in maintaining host immune homeostasis, a process that involves dynamic modulations of host organelles. The Golgi apparatus is increasingly perceived as a host organelle functioning as a critic
Externí odkaz:
https://doaj.org/article/1abfb1d7784f4823bb443206c12e36eb
Autor:
Qingqing Hu, Huichun Tong, Jing Wang, Pupu Ge, Lin Zhu, Cuihua Liu, Jing-ren Zhang, Xiuzhu Dong
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Aquaporins, integral membrane proteins widely distributed in organisms, facilitate the transport of water, glycerol, and other small uncharged solutes across cellular membranes and play important physiological roles in eukaryotes. However, c
Externí odkaz:
https://doaj.org/article/9c14c84027094f8cb93c9a5881b00d83
Autor:
Qiyao Chai, Xudong Wang, Lihua Qiang, Yong Zhang, Pupu Ge, Zhe Lu, Yanzhao Zhong, Bingxi Li, Jing Wang, Lingqiang Zhang, Dawang Zhou, Wei Li, Wenzhu Dong, Yu Pang, George Fu Gao, Cui Hua Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Ubiquitin (Ub)-mediated xenophagy is important in defense against Mycobacterium tuberculosis (Mtb). Here, Chai et al. describe autophagy triggering by Ub binding to the Mtb surface protein Rv1468c, and show that its deletion leads to increased bacter
Externí odkaz:
https://doaj.org/article/74d2a3ea423348b2880c9a031a9391b8
Autor:
Jing Wang, Pupu Ge, Lihua Qiang, Feng Tian, Dongdong Zhao, Qiyao Chai, Mingzhao Zhu, Rongbin Zhou, Guangxun Meng, Yoichiro Iwakura, George Fu Gao, Cui Hua Liu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Mycobacterium tuberculosis secretes a protein, PtpA, that dephosphorylates proteins in the host cell cytoplasm, weakening immune responses. Here, the authors show that PtpA also enters the nucleus, affects the expression of several host genes, and pr
Externí odkaz:
https://doaj.org/article/465a63bc5e6745cab574ea4a454e9961
Autor:
Jing Wang, Dongdong Zhao, Zehui Lei, Pupu Ge, Zhe Lu, Qiyao Chai, Yong Zhang, Lihua Qiang, Yang Yu, Xinwen Zhang, Bingxi Li, Shu Zhu, Lingqiang Zhang, Cui Hua Liu
Publikováno v:
Cellular & Molecular Immunology. 20:158-174
Dysregulation of gut homeostasis is associated with irritable bowel syndrome (IBS), a chronic functional gastrointestinal disorder affecting approximately 11.2% of the global population. The poorly understood pathogenesis of IBS has impeded its treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbd32fc86e2698a3e6e4b06fd570169
https://doi.org/10.1038/s41423-022-00963-1
https://doi.org/10.1038/s41423-022-00963-1
Autor:
Xi Yang, Cui Hua Liu, Ling Li, Pupu Ge, Lihua Qiang, Qiyao Chai, Yong Zhang, Zehui Lei, Yu Cui, Dongdong Zhao, Zhe Lu, Bo Wu, Jing Wang, Lingqiang Zhang, Conghui Han
Publikováno v:
The FASEB Journal. 34:14631-14644
During spaceflight, astronauts are subjected to various physical stressors including microgravity, which could cause immune dysfunction and thus potentially predispose astronauts to infections and illness. However, the mechanisms by which microgravit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91206e48f03c6f153c70ccf263853495
https://doi.org/10.1096/fj.202001428r
https://doi.org/10.1096/fj.202001428r
Autor:
Cui Hua Liu, Pupu Ge, Lin Zhu, Qingqing Hu, Jing Wang, Xiuzhu Dong, Jing-Ren Zhang, Huichun Tong
Publikováno v:
mBio
mBio, Vol 12, Iss 4 (2021)
mBio, Vol 12, Iss 4 (2021)
Aquaporins, integral membrane proteins widely distributed in organisms, facilitate the transport of water, glycerol, and other small uncharged solutes across cellular membranes and play important physiological roles in eukaryotes. However, characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e485c496b191a69020719872e7c79a88
https://pubmed.ncbi.nlm.nih.gov/34399618
https://pubmed.ncbi.nlm.nih.gov/34399618
Autor:
Jing Wang, Qiyao Chai, Yanzhao Zhong, Lingqiang Zhang, Yong Zhang, Wenzhu Dong, Cui Hua Liu, George F. Gao, Pupu Ge, Yu Pang, Dawang Zhou, Wei Li, Xudong Wang, Bingxi Li, Zhe Lu, Lihua Qiang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
Ubiquitin-mediated xenophagy, a type of selective autophagy, plays crucial roles in host defense against intracellular pathogens including Mycobacterium tuberculosis (Mtb). However, the exact mechanism by which host ubiquitin targets invaded microbes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b3cf941b4a52b483437795cf8b5f37
https://doaj.org/article/74d2a3ea423348b2880c9a031a9391b8
https://doaj.org/article/74d2a3ea423348b2880c9a031a9391b8