Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Punsaldulam Dashnyam"'
Autor:
Hsien-Ya Lin, Chia-Yu Chen, Ting-Chien Lin, Lun-Fu Yeh, Wei-Che Hsieh, Shijay Gao, Pierre-Alain Burnouf, Bing-Mae Chen, Tung-Ju Hsieh, Punsaldulam Dashnyam, Yen-Hsi Kuo, Zhijay Tu, Steve R. Roffler, Chun-Hung Lin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Hsien-Ya Lin, Chia-Yu Chen, Ting-Chien Lin and colleagues perform structure-guided modifications of the compound uronic isofagomaine in order to engineer a highly specific and potent inhibitor of gut bacterial β-glucuronidases (GUSs). The authors pr
Externí odkaz:
https://doaj.org/article/fb39bb5584a546bea3aca76fb3fd4c02
Autor:
Punsaldulam Dashnyam, Ramesh Mudududdla, Tung-Ju Hsieh, Ting-Chien Lin, Hsien-Ya Lin, Peng-Yuan Chen, Chia-Yi Hsu, Chun-Hung Lin
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Gut bacterial β-D-glucuronidases (GUSs) catalyze the removal of glucuronic acid from liver-produced β-D-glucuronides. These reactions can have deleterious consequences when they reverse xenobiotic metabolism. The human gut contains hundred
Externí odkaz:
https://doaj.org/article/0b6371ff0cd6400d83e8e0397189f8c8
Autor:
Hsien-Ya Lin, Lun-Fu Yeh, Shijay Gao, Punsaldulam Dashnyam, Wei-Che Hsieh, Chun-Hung Lin, Chia-Yu Chen, Zhijay Tu
Publikováno v:
Journal of Medicinal Chemistry. 63:4617-4627
Selective inhibitors of gut bacterial β-glucuronidases (GUSs) are of particular interest in the prevention of xenobiotic-induced toxicities. This study reports the first structure-activity relationships on potency and selectivity of several iminocyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9380d697d84c43e9d49ad383f160ce97
https://doi.org/10.1021/acs.jmedchem.9b01918
https://doi.org/10.1021/acs.jmedchem.9b01918
Autor:
Chun-Hung Lin, Ramesh Mudududdla, Ting-Chien Lin, Chia-Yi Hsu, Hsien-Ya Lin, Peng-Yuan Chen, Tung-Ju Hsieh, Punsaldulam Dashnyam
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Gut bacterial β-D-glucuronidases (GUSs) catalyze the removal of glucuronic acid from liver-produced β-D-glucuronides. These reactions can have deleterious consequences when they reverse xenobiotic metabolism. The human gut contains hundreds of GUSs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8702f292a2eac6b47a073628a72d11
https://doaj.org/article/0b6371ff0cd6400d83e8e0397189f8c8
https://doaj.org/article/0b6371ff0cd6400d83e8e0397189f8c8
Autor:
Punsaldulam Dashnyam, 朋莎朗
107
Gut bacterial β-D-glucuronidases (GUSs) catalyze the removal of glucuronic acid from liver-produced β-D-glucuronides. These reactions can have deleterious consequences when they reverse xenobiotic metabolism. The human gut contains hundred
Gut bacterial β-D-glucuronidases (GUSs) catalyze the removal of glucuronic acid from liver-produced β-D-glucuronides. These reactions can have deleterious consequences when they reverse xenobiotic metabolism. The human gut contains hundred
Externí odkaz:
http://ndltd.ncl.edu.tw/cgi-bin/gs32/gsweb.cgi/login?o=dnclcdr&s=id=%22107NCHU5111019%22.&searchmode=basic
Autor:
S. Alvarez, Michael1 (AUTHOR), Billones, Junie2 (AUTHOR), Lin, Chun-Hung3 (AUTHOR), Heralde, Francisco4 (AUTHOR)
Publikováno v:
Pharmacognosy Magazine. 2021Sup2, Vol. 17, p268-277. 10p.
Autor:
Lin, Hsien-Ya1,2, Chen, Chia-Yu1,2, Lin, Ting-Chien1,2, Yeh, Lun-Fu1, Hsieh, Wei-Che1, Gao, Shijay1, Burnouf, Pierre-Alain3, Chen, Bing-Mae3, Hsieh, Tung-Ju1, Dashnyam, Punsaldulam1, Kuo, Yen-Hsi1, Tu, Zhijay1, Roffler, Steve R.3,4 sroff@ibms.sinica.edu.tw, Lin, Chun-Hung1,2,5,6 chunhung@gate.sinica.edu.tw
Publikováno v:
Communications Biology. 3/4/2021, Vol. 4 Issue 1, p1-10. 10p.
Autor:
Dashnyam, Punsaldulam1,2,3, Mudududdla, Ramesh2, Hsieh, Tung-Ju2, Lin, Ting-Chien2, Lin, Hsien-Ya2, Chen, Peng-Yuan2, Hsu, Chia-Yi2, Lin, Chun-Hung1,2,4,5 chunhung@gate.sinica.edu.tw
Publikováno v:
Scientific Reports. 11/6/2018, Vol. 8 Issue 1, p1-1. 1p.