Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Punnajit Lim"'
Autor:
Punnajit Lim, Chih-Hong Lou, Yusuke Higuchi, Jia-Ling Teo, Xiaohui Hu, Nyam-Osor Chimge, Patrick T. Fueger, Keisuke Chosa, Elizabeth Melendez, Keane K. Y. Lai, Masaya Ono, Michael G. Kahn, John Termini, Cu Nguyen
Publikováno v:
Cancers, Vol 13, Iss 5884, p 5884 (2021)
Cancers; Volume 13; Issue 23; Pages: 5884
Cancers
Cancers; Volume 13; Issue 23; Pages: 5884
Cancers
Simple Summary The coupling of metabolism with cellular status is critically important and highly evolutionarily conserved. However, how cells coordinate metabolism with transcription as they change their status is not clear. Utilizing multiomic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd3fbb1c5848e252ef414dd7303e0e6
https://www.mdpi.com/2072-6694/13/23/5884
https://www.mdpi.com/2072-6694/13/23/5884
Autor:
Matan Soll, Zeev Gross, Punnajit Lim, Angel J. Di Bilio, John Termini, Mike H. B. Gray, Bradley J. Brennan, Harry B. Gray, Lawrence M. Henling, Scott C. Virgil, Julius Oppenheim
Publikováno v:
Inorg Chem
In aqueous media, hydrophobic metallocorroles form nanoparticles that are potential theranostic anticancer agents. We have analyzed the electronic and Raman spectra of Al(III), Ga(III), and Au(III) corrole nanoparticles (and made comparisons with DFT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b9bdda20449fa4f430bb6b3d8ce8dd
https://doi.org/10.1021/acs.inorgchem.9b01441
https://doi.org/10.1021/acs.inorgchem.9b01441
Autor:
Harry B. Gray, John Termini, Benny Zhitomirsky, Qiu-Cheng Chen, Matan Soll, Yehuda G. Assaraf, Zeev Gross, Punnajit Lim
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-17 (2020)
Cell Death Discovery, Vol 6, Iss 1, Pp 1-17 (2020)
Development of novel therapeutic strategies to eradicate malignant tumors is of paramount importance in cancer research. In a recent study, we have introduced a facile protocol for the preparation of corrole-protein nanoparticles (NPs). These NPs con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e618c0675c62b6bc02bb2d76a2ef7c28
http://europepmc.org/articles/PMC7387447
http://europepmc.org/articles/PMC7387447
Autor:
Harry B. Gray, Angel J. Di Bilio, Qiu-Cheng Chen, John Termini, Irena Saltsman, Ruijie D. Teo, Mona Shahgholi, Matan Soll, Sarah Cohen, Tridib K. Goswami, Punnajit Lim, Zeev Gross
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Recent work has highlighted the potential of metallocorroles as versatile platforms for the development of drugs and imaging agents, since the bioavailability, physicochemical properties and therapeutic activity can be dramatically altered by metal i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213719195432a8124cf2b7b1f392e26f
https://resolver.caltech.edu/CaltechAUTHORS:20190219-134141446
https://resolver.caltech.edu/CaltechAUTHORS:20190219-134141446
Autor:
Xueli Liu, Richard Jaramillo, Daniel Tamae, Sarah C. Shuck, Steven E. Bates, Punnajit Lim, John Termini, Timothy R. O'Connor, Sandrine Lacoste, Yin S. Chan
Publikováno v:
Chemical research in toxicology, vol 30, iss 2
More precise identification and treatment monitoring of prediabetic/diabetic individuals will require additional biomarkers to complement existing diagnostic tests. Candidates include hyperglycemia-induced adducts such as advanced glycation end produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7586d02af2470d0cfd23b795943c4126
https://pubmed.ncbi.nlm.nih.gov/28107623
https://pubmed.ncbi.nlm.nih.gov/28107623
Autor:
Joshua H. Palmer, Punnajit Lim, Melanie A. Pribisko, Robert H. Grubbs, John Termini, Harry B. Gray
Publikováno v:
The Journal of urology. 196(5)
We report derivatives of gallium(III) tris(pentafluorophenyl)corrole, 1 [Ga(tpfc)], with either sulfonic (2) or carboxylic acids (3, 4) as macrocyclic ring substituents: the aminocaproate derivative, 3 [Ga(ACtpfc)], demonstrated high cytotoxic activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7091e633050b71a019db79a08c0a2dff
https://pubmed.ncbi.nlm.nih.gov/27044076
https://pubmed.ncbi.nlm.nih.gov/27044076
Autor:
John Termini, Irena Saltsman, Atif Mahammed, Punnajit Lim, Harry B. Gray, Zeev Gross, Zoya Okun
Publikováno v:
Chemical Research in Toxicology. 25:400-409
A gallium(III)-substituted amphiphilic corrole noncovalently associated with a targeting protein was previously found by us to confer promising cytotoxic and antitumor activities against a breast cancer cell line and a mouse xenograft breast cancer m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d039773879b41d51522ed4f40bf5041
https://doi.org/10.1021/tx200452w
https://doi.org/10.1021/tx200452w
Autor:
Luis R. De Jesus, Gerald E. Wuenschell, Sarah C. Shuck, John Termini, Claudia M. Kowolik, Rahul Jandial, Mike Y. Chen, Daniel Tamae, Punnajit Lim, Ching Ouyang, Alexandra K Ciminera, Josh Neman
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 2; Pages: 406
International Journal of Molecular Sciences, Vol 19, Iss 2, p 406 (2018)
International Journal of Molecular Sciences; Volume 19; Issue 2; Pages: 406
International Journal of Molecular Sciences, Vol 19, Iss 2, p 406 (2018)
Cancers that exhibit the Warburg effect may elevate expression of glyoxylase 1 (GLO1) to detoxify the toxic glycolytic byproduct methylglyoxal (MG) and inhibit the formation of pro-apoptotic advanced glycation endproducts (AGEs). Inhibition of GLO1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b876a53466e9e309aa965b0462e9dbde
https://doi.org/10.3390/ijms19020406
https://doi.org/10.3390/ijms19020406
Autor:
John Termini, Harry B. Gray, Grace Y. Tang, Ryan K. Henning, Melanie A. Pribisko, Robert H. Grubbs, Punnajit Lim
Publikováno v:
Journal of Visualized Experiments.
Chemotherapy often involves broad-spectrum cytotoxic agents with many side effects and limited targeting. Corroles are a class of tetrapyrrolic macrocycles that exhibit differential cytostatic and cytotoxic properties in specific cell lines, dependin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837f4702fd595b1c21fe2cdfb5a8ac43
https://doi.org/10.3791/52355
https://doi.org/10.3791/52355
Autor:
Gerd P. Pfeifer, Gerald E. Wuenschell, Punnajit Lim, John Termini, Dong-Hyun Lee, Vanessa Holland, Henry Rodriguez
Publikováno v:
Biochemistry. 43:15339-15348
Endogenous DNA damage induced by lipid peroxidation is believed to play a critical role in carcinogenesis. Lipid peroxidation generates free radical intermediates (primarily peroxyl radicals, ROO(*)) and electrophilic aldehydes as the principal genot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b252009fdf6a854838ae3fbcd1703c6e
https://doi.org/10.1021/bi048276x
https://doi.org/10.1021/bi048276x