Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pung-Sok Lee"'
Publikováno v:
Archives of Pharmacal Research. 33:1375-1387
A new triglyceride-free propofol microemulsion for intravenous injection was formulated using nonionic surfactants, poloxamers and polyethylene glycol 660 hydroxystearate. The aim of this investigation was to evaluate the formulation for storage stab
Publikováno v:
Journal of Pharmaceutical Investigation. 40:85-90
【Docetaxel-loaded liposomes were prepared by emulsion-solvent evaporation method, then coated with chitosan at room temperature and lyophilized. This system was designed in order to improve solubility and stability of docetaxel in the GI tract for
Publikováno v:
Journal of Korean Pharmaceutical Sciences. 39:269-273
The objective of this investigation was to develop a gastro-retentive(GR) dosage form of gabapentin and was to evaluate of its dissolution characteristics. GR tablet consists of expandable core tablet matrix and semi-permeable membrane coating. Polox
Autor:
Hwan-Soo Yoo, Kyoung-Mi Lee, Pung Sok Lee, Sukgil Song, Jin Tae Hong, Dae Hwan Shin, Youn Bok Chung, Dong-Cheul Moon
Publikováno v:
Archives of Pharmacal Research. 30:372-380
Preclinical studies are currently underway to examine the potential antitumor effects of a 1:1 mixture of acriflavine (ACF; CAS 8063-24-9) and guanosine. Guanosine potentiates the anti-cancer activity of some compounds. However, the effects of guanos
Autor:
Pung-Sok Lee, Kyoung-Mi Lee, Dae Hwan Shin, Jung-Yeol Lee, So-Young Lee, Koo-Hyun Kwon, Youn-Bok Chung
Publikováno v:
Journal of Korean Pharmaceutical Sciences. 36:377-383
The purpose of the present study was to examine the pharmacokinetic characteristics of arsenic hexaoxide(), a novel anticancer compound, after i.v. bolus and oral administration in rats. We developed an ICP-Mass based method to analyze arsenic hexaox
Autor:
Jong Hwan Sung, Tae Won Song, Jin-Yi Han, Oh-Seung Kwon, Sukgil Song, Pung Sok Lee, Youn Bok Chung
Publikováno v:
International Journal of Pharmaceutics. 316:29-36
In an effort to improve the bioavailability (BA) of the insoluble compound 20-O-(beta-d-glucopyranosyl)-20(S)-protopanaxadiol (IH901), we prepared beta-cyclodextrin (betaCD) and hydroxypropyl-beta-cyclodextrin (HPbetaCD) inclusion complexes containin
Autor:
Pung Sok Lee, Dong Ju Son, Chang-Soo Kim, Dong‐Cheul Moon, Nam Hee Kim, Youn Bok Chung, Min Kyo Jeoung, Jin Tae Hong
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 28:3205-3216
We developed a liquid chromatography‐tandem mass spectrometric (LC‐MS/MS) method for the determination of a ginseng saponin metabolite, IH901 or compound K (20‐O‐β‐D‐glucopyranosyl‐20(S)‐protopanaxadiol) in rat plasma. The method inv
Autor:
Sukgil Song, Im-Sook Song, Youn Bok Chung, Chang-Koo Shim, Pung Sok Lee, Suk-Jae Chung, Tae Ha Shin
Publikováno v:
Archives of Pharmacal Research. 26:338-343
The purpose of the present study was to investigate the bidirectional transport of 1-anilino-8-naphthalene sulfonate (ANS) using isolated rat hepatocytes. The initial uptake rate of ANS by isolated hepatocytes was determined. The uptake process of AN
Publikováno v:
Planta medica. 72(3)
We investigated the pharmacokinetic characteristics of 20- O-(beta-D-glucopyranosyl)-20(S)-protopanaxadiol (IH-901), a metabolite that is formed by intestinal bacteria, after its intravenous (i.v.) or oral administration in rats. We developed an LC/M
Publikováno v:
Archives of pharmacal research. 26(1)
The objective of the present study was to investigate the uptake process of 4-Phenylazobenzoxycarbonyl-Pro-Leu-Gly-Pro-D-Arg (Pz-peptide), a hydrophilic and collagenase-labile pentapeptide, by isolated hepatocytes. For comparison, the uptake of Pz-pe