Design of Chiral β-Double Helices from γ-Peptide Foldamers.

Autor: Pahan S; Department of Chemistry, Indian Institute of Science Education and Research (IISER), Pune, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India., Dey S; Department of Chemistry, Indian Institute of Science Education and Research (IISER), Pune, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India., George G; Department of Chemistry, Indian Institute of Science Education and Research (IISER), Pune, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India., Mahapatra SP; Department of Chemistry, Indian Institute of Science Education and Research (IISER), Pune, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India., Puneeth Kumar DR; Department of Chemistry, Indian Institute of Science Education and Research (IISER), Pune, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India., Gopi HN; Department of Chemistry, Indian Institute of Science Education and Research (IISER), Pune, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Jan 08; Vol. 63 (2), pp. e202316309. Date of Electronic Publication: 2023 Dec 07.

Proteolytically Stable ααγ-Hybrid Peptides Inhibit the Aggregation and Cytotoxicity of Aβ 42 .

Autor: Puneeth Kumar DR; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Nalawade SA; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Pahan S; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Singh M; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Senapati DK; NMR Research Centre, Indian Institute of Science, Bangalore 560012, India., Roy S; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Dey S; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Toraskar SU; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008, India., Raghothama S; NMR Research Centre, Indian Institute of Science, Bangalore 560012, India., Gopi HN; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008, India.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2023 Sep 20; Vol. 14 (18), pp. 3398-3408. Date of Electronic Publication: 2023 Sep 01.

Cyclization of N -Boc-( E )-α,β-unsaturated γ-amino acid active esters into N -Boc-( Z )-α,β-unsaturated γ-lactams through E → Z isomerization.

Autor: Singh M; Department of Chemistry, Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pashan, Pune-411008, India. hn.gopi@iiserpune.ac.in., Kumar M; Department of Chemistry, Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pashan, Pune-411008, India. hn.gopi@iiserpune.ac.in., Nalawade SA; Department of Chemistry, Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pashan, Pune-411008, India. hn.gopi@iiserpune.ac.in., Puneeth Kumar DR; Department of Chemistry, Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pashan, Pune-411008, India. hn.gopi@iiserpune.ac.in., Gopi HN; Department of Chemistry, Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pashan, Pune-411008, India. hn.gopi@iiserpune.ac.in.

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2023 May 10; Vol. 21 (18), pp. 3766-3769. Date of Electronic Publication: 2023 May 10.

A cationic amphiphilic peptide chaperone rescues Aβ 42 aggregation and cytotoxicity.

Autor: Puneeth Kumar DR; Department of Chemistry, Indian Institute of Science Education and Research Dr. Homi Bhabha Road, Pashan Pune-411008 India hn.gopi@iiserpune.ac.in., Reja RM; Department of Chemistry, Indian Institute of Science Education and Research Dr. Homi Bhabha Road, Pashan Pune-411008 India hn.gopi@iiserpune.ac.in., Senapati DK; NMR Research Centre, Indian Institute of Science Bangalore-560012 India., Singh M; Department of Chemistry, Indian Institute of Science Education and Research Dr. Homi Bhabha Road, Pashan Pune-411008 India hn.gopi@iiserpune.ac.in., Nalawade SA; Department of Chemistry, Indian Institute of Science Education and Research Dr. Homi Bhabha Road, Pashan Pune-411008 India hn.gopi@iiserpune.ac.in., George G; NMR Research Centre, Indian Institute of Science Bangalore-560012 India., Kaul G; Division of Microbiology and Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute Sitapur Road, Sector 10, Janakipuram Extension Lucknow-226031 Uttar Pradesh India.; AcSIR: Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 India., Akhir A; Division of Microbiology and Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute Sitapur Road, Sector 10, Janakipuram Extension Lucknow-226031 Uttar Pradesh India., Chopra S; Division of Microbiology and Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute Sitapur Road, Sector 10, Janakipuram Extension Lucknow-226031 Uttar Pradesh India.; AcSIR: Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 India., Raghothama S; NMR Research Centre, Indian Institute of Science Bangalore-560012 India., Gopi HN; Department of Chemistry, Indian Institute of Science Education and Research Dr. Homi Bhabha Road, Pashan Pune-411008 India hn.gopi@iiserpune.ac.in.

Publikováno v: RSC medicinal chemistry [RSC Med Chem] 2022 Dec 10; Vol. 14 (2), pp. 332-340. Date of Electronic Publication: 2022 Dec 10 (Print Publication: 2023).