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pro vyhledávání: '"Puma Chandra Ray"'
Autor:
Christopher N. Boddy, Frajovon Talley, Stephen R. Houghton, L. Nagaprasada Rao, Jack Melton, Shaik Muneer, Nylea Bivins, Gottumukkala V. Subbaraju, David S. Teager, Adrian Williams, Tricia Silverton, Stephen R. Byrn, Nardla Gopal Reddy, K. Chandra Shekar, Daniel T. Smith, S. Tirumala Jagadeesh, David H. Brown Ripin, R. Venkateswara Rao, Puma Chandra Ray, Kelly K. Catlin, Rodger W. Stringham, Joseph M. Fortunak, Shaik Mahaboob Basha, Ravi Mallikarjuna Reddy, K. Anesh Kumar
Publikováno v:
Organic Process Research & Development. 14:1194-1201
The three-step manufacturing process used in the synthesis of tenofovir disoproxil fumarate (1) was studied and optimized, leading to a more productive and robust process. The yield was improved from about 13% overall to 24%. Key process improvements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52ee6a6c0d36118dba25441a3778323a
https://doi.org/10.1021/op1001337
https://doi.org/10.1021/op1001337
