Zobrazeno 1 - 10
of 375
pro vyhledávání: '"Pulmonary arterial smooth muscle cells"'
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Objectives In this study, we investigated whether neural precursor cell–expressed developmentally down-regulated gene 4-like (NEDD4L) is the E3 enzyme of angiotensin-converting enzyme 2 (ACE2) and whether NEDD4L degrades ACE2 via ubiquitin
Externí odkaz:
https://doaj.org/article/15944c906aeb4bb4bb017e199438f546
Autor:
Yi-Chia Wu, Wei-Ting Wang, Ming-Chun Yang, Yu-Tsun Su, Jwu-Lai Yeh, Jong-Hau Hsu, Jiunn-Ren Wu
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-16 (2023)
Abstract Background Abnormal remodeling of the pulmonary vasculature, characterized by the proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) along with dysregulated glycolysis, is a pathognomonic feature of pulmonary arte
Externí odkaz:
https://doaj.org/article/cc7bb2c564ff45e18571fe0ff1d3f604
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background Pulmonary arterial hypertension (PAH) is a rare but fatal cardiopulmonary disease mainly characterized by pulmonary vascular remodeling. Aberrant expression of circRNAs has been reported to play a crucial role in pulmonary vascula
Externí odkaz:
https://doaj.org/article/354a8d664200411b9e6ad797708c0a09
Autor:
Patrick Crosswhite, Zhongjie Sun
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 677 (2024)
Objective: The level of tumor necrosis factor-α (TNF-α) is upregulated during the development of pulmonary vascular remodeling and pulmonary hypertension. A hallmark of pulmonary arterial (PA) remodeling is the excessive proliferation of PA smooth
Externí odkaz:
https://doaj.org/article/d11d19de40b940008ac084a1b4b9c103
Akademický článek
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Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/ca9e25a2d3fb4009b76af54acd14140e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Pulmonary hypertension (PH) is a refractory and fatal disease characterized by excessive pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary arterial smooth muscle cells (PASMCs), dysfunction of pulmonary arter
Externí odkaz:
https://doaj.org/article/c830952f0b964cf8be36e5260b6b7390
Autor:
Chaoyi Ye, Guili Lian, Tingjun Wang, Ai Chen, Weixiao Chen, Jin Gong, Li Luo, Huajun Wang, Liangdi Xie
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background The zinc transporter ZIP12 is a membrane-spanning protein that transports zinc ions into the cytoplasm from the extracellular space. Recent studies demonstrated that upregulation of ZIP12 is involved in elevation of cytosolic free
Externí odkaz:
https://doaj.org/article/48a83e928a91467b9685fafe469c64fd
Autor:
Mingzhou Guo, Mengzhe Zhang, Xiaopei Cao, Xiaoyu Fang, Ke Li, Lu Qin, Yuanzhou He, Jianping Zhao, Yongjian Xu, Xiansheng Liu, Xiaochen Li
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Hypoxic pulmonary hypertension (HPH) is a chronic progressive advanced disorder pathologically characterized by pulmonary vascular remodeling. Notch4 as a cell surface receptor is critical for vascular development. However, little
Externí odkaz:
https://doaj.org/article/66bdb01cc6aa4a3cb166ec10da21e376
Autor:
Kathrin Malkmus, Monika Brosien, Fenja Knoepp, Lisa Schaffelhofer, Friedrich Grimminger, Christoph Rummel, Thomas Gudermann, Alexander Dietrich, Lutz Birnbaumer, Norbert Weissmann, Simone Kraut
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Chronic hypoxia-induced pulmonary hypertension (CHPH) is a severe disease that is characterized by increased proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) leading to pulmonary vascular remodeling. The resulting increa
Externí odkaz:
https://doaj.org/article/61661b96150f4e018e0f1ea791d97ae1