Zobrazeno 1 - 10
of 2 428
pro vyhledávání: '"Pulmonary Drug Delivery"'
Publikováno v:
Smart Materials in Medicine, Vol 5, Iss 3, Pp 348-358 (2024)
Acute respiratory distress syndrome (ARDS), a severe form of acute lung injury (ALI), is the major cause of intensive care unit death worldwide. ALI/ARDS is a common condition characterized by a storm of potent inflammatory cytokines. Lung delivery o
Externí odkaz:
https://doaj.org/article/536a7dbaf15641229f29fb30955803e5
Autor:
Aura Rocío Hernández, Ekaterina Bogdanova, Jesus E. Campos Pacheco, Vitaly Kocherbitov, Mikael Ekström, Georgia Pilkington, Sabrina Valetti
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
Pulmonary delivery and formulation of biologics are among the more complex and growing scientific topics in drug delivery. We herein developed a dry powder formulation using disordered mesoporous silica particles (MSP) as the sole excipient and lysoz
Externí odkaz:
https://doaj.org/article/48fe2cead058404c9d35312453e9b037
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 7529-7546 (2024)
Yongpeng Huang, Hui Tang, Xiangyan Meng, Dongxin Liu, Yanli Liu, Bo Chen, Zhiyun Zou State Key Laboratory of NBC Protection for Civilian, Beijing, People’s Republic of ChinaCorrespondence: Bo Chen; Zhiyun Zou, Email NBC_BoChen@163.com; zouzhiyun65@
Externí odkaz:
https://doaj.org/article/b3a419f0f6c24695b2e63ab18594ff22
Autor:
Aseel Khaled Mohammad AL-Sarayrah, Samer Hasan Hussein-Al-Ali, Mike Khalil Haddad, Dalia Kalil
Publikováno v:
Indonesian Journal of Chemistry, Vol 24, Iss 2, Pp 427-443 (2024)
Nanocomposite formulation is a suitable technology that enables the development of successful dry powder inhalers. The methotrexate (MTX) and polyamide-disulfide (polymer) were used as a model to form MTX-polymer nanocomposites. Different amounts of
Externí odkaz:
https://doaj.org/article/d654f78757d2414594ae5e1c381b0b1a
Publikováno v:
Chemical Physics Impact, Vol 8, Iss , Pp 100644- (2024)
Biopolymer based nanomedicine for pulmonary delivery is safe and effective in lung cancer therapy. Current work addressed marine polysaccharide fucoidan fabricated bosutinib nanocrystals (FBNC) as dry powder for inhalation (DPI). Microscopic characte
Externí odkaz:
https://doaj.org/article/39e69ad766ea41f3b33b0170e5142123
Akademický článek
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Autor:
Aleksandra Rzewińska, Jakub Szlęk, Damian Dąbrowski, Ewelina Juszczyk, Katarzyna Mróz, Heikki Räikkönen, Mia Siven, Maciej Wieczorek, Przemysław Dorożyński
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1157 (2024)
The pursuit of targeted therapies for cytokine-dependent diseases has led to the discovery of Janus kinase (JAK) inhibitors, a promising class of drugs. Among them, CPL409116, a selective dual JAK and rho-associated protein kinase inhibitor (ROCK), h
Externí odkaz:
https://doaj.org/article/6049c0b9f7b84a35a5814f9bec6fdeb6
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1061 (2024)
Ivermectin (IVM), a drug originally used for treating parasitic infections, is being explored for its potential applications in cancer therapy. Despite the promising anti-cancer effects of IVM, its low water solubility limits its bioavailability and,
Externí odkaz:
https://doaj.org/article/b0df18690c004db383d6d91cdfe8b3bd
Autor:
Bin Wang, Lin Wang, Qian Yang, Yuming Zhang, Tang Qinglai, Xinming Yang, Zian Xiao, Lanjie Lei, Shisheng Li
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100966- (2024)
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with few systemic side effects. In addition, it is non-invasive and has good patient compliance, making it a highly promising drug delivery mode. However, there
Externí odkaz:
https://doaj.org/article/03a23a2da0254b35a9253fa4e206977c
Autor:
Allana Carvalho Silva, Mirsiane Pascoal Costa, Thiago Medeiros Zacaron, Kézia Cristine Barbosa Ferreira, Wilson Rodrigues Braz, Rodrigo Luiz Fabri, Frédéric Jean Georges Frézard, Frederico Pittella, Guilherme Diniz Tavares
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 969 (2024)
Lung cancer is the leading cause of cancer-related mortality worldwide, largely due to the limited efficacy of anticancer drugs, which is primarily attributed to insufficient doses reaching the lungs. Additionally, patients undergoing treatment exper
Externí odkaz:
https://doaj.org/article/a3542f7a8a4e418f82a8997d996effb3