Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Pulla Reddy Boggu"'
Autor:
Younggyu Kong, Pulla Reddy Boggu, Gi Min Park, Yeon Su Kim, Seong Hwan An, In Su Kim, Young Hoon Jung
Publikováno v:
Molecules, Vol 27, Iss 8, p 2603 (2022)
Eliglustat (Cerdelga®, Genzyme Corp. Cambridge, MA, USA) is an approved drug for a non-neurological type of Gaucher disease. Herein, we describe the total synthesis of eliglustat 1 starting from readily available 1,4-benzodioxan-6-carbaldehyde via S
Externí odkaz:
https://doaj.org/article/5d86724515634b399d18aba6128765d0
Publikováno v:
Bulletin of the Korean Chemical Society. 41:468-471
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5a84321d1dee19743ace03d945f306e
https://doi.org/10.1002/bkcs.11995
https://doi.org/10.1002/bkcs.11995
Autor:
Sun Ju Kong, Gibeom Nam, Pulla Reddy Boggu, Gi Min Park, Ji Eun Kang, Hyun-Ju Park, Young Hoon Jung
Publikováno v:
Bioorganic & Medicinal Chemistry. 79:117154
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0362e7a28c0e28c085eac6ec88cfa96
https://doi.org/10.1016/j.bmc.2023.117154
https://doi.org/10.1016/j.bmc.2023.117154
Autor:
Gi Min Park, Sun Ju Kong, Jae Hyeon Park, Ji Eun Kang, Sung Hwan An, Hyung Sik Kim, In Su Kim, Pulla Reddy Boggu, Young Hoon Jung
Publikováno v:
Carbohydrate Research. 524:108746
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3eaa8e682f6bfd9e8d5686afa409fc
https://doi.org/10.1016/j.carres.2023.108746
https://doi.org/10.1016/j.carres.2023.108746
Publikováno v:
Tetrahedron. 116:132809
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81404cfc0663f24abaca3a8bde13b25e
https://doi.org/10.1016/j.tet.2022.132809
https://doi.org/10.1016/j.tet.2022.132809
Autor:
Sang-Hun Jung, Niti Sharma, Pulla Reddy Boggu, Eeda Venkateswararao, Jong Seong Kang, Manoj Manickam
Publikováno v:
Bioorganicmedicinal chemistry. 28(22)
To identify novel potent cardiac myosin activator, a series of diphenylalkylisoxazol-5-amine compounds 4–7 have been synthesized and evaluated for cardiac myosin ATPase activation. Among the 37 compounds, 4a (CMA at 10 µM = 81.6%), 4w (CMA at 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f04626f8af40652645ddd565d27db2
https://pubmed.ncbi.nlm.nih.gov/33007555
https://pubmed.ncbi.nlm.nih.gov/33007555
Autor:
Manoj Manickam, Thanigaimalai Pillaiyar, Pulla Reddy Boggu, Hitesh B. Jalani, Eeda Venkateswararao, Niti Sharma, Sang-Hun Jung
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2369-2374
To explore novel cardiac myosin activator, a series of diphenylalkyl substituted 1,3,4-oxadiazoles and 1,2,4-oxadiazoles have been prepared and tested for cardiac myosin ATPase activation in vitro. In all cases, three carbon spacer between the oxadia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cff07405dc2153d86fef0f044cf6f5
https://doi.org/10.1016/j.bmcl.2018.06.031
https://doi.org/10.1016/j.bmcl.2018.06.031
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2023-2028
To establish the structure-activity relationship of 5-hydroxy-1,4-naphthoquinones toward anticancer activity, a series of its derivatives were prepared and tested for the activity (IC50 in µM) against three cell lines; colo205 (colon adenocarcinoma)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b135803cdb6a68b0a84e09f0d9c3f21d
https://doi.org/10.1016/j.bmcl.2018.04.060
https://doi.org/10.1016/j.bmcl.2018.04.060
Publikováno v:
European Journal of Medicinal Chemistry. 152:65-75
A novel series of 2-benzyl-1-indanone analogs were investigated as IL-5 inhibitory activity. Among the synthesized compounds, 7-(cyclohexylmethoxy)-2-(4-hydroxybenzyl)-2,3-dihydro-1H-inden-1-one (7s, 100.0% inhibition at 30 μM, IC50 = 4.0 μM), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f12f7195b156822f24b1de833c1bb71
https://doi.org/10.1016/j.ejmech.2018.04.030
https://doi.org/10.1016/j.ejmech.2018.04.030
Publikováno v:
Archives of Pharmacal Research. 41:251-258
For confirming the role of five membered ring of imidazolidinone moiety of N-arylsulfonylimidazolidinones (7) previously reported with highly potent anticancer agent, a series of N-arylsulfonylpyrimidones (10a–g) and N-arylsulfonyltetrahydropyrimid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19355c74651e0048f4132472e0fb50b9
https://doi.org/10.1007/s12272-018-1003-9
https://doi.org/10.1007/s12272-018-1003-9