Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Pulin Che"'
Autor:
Jennifer L Larson-Casey, Chao He, Pulin Che, Meimei Wang, Guoqiang Cai, Young-Il Kim, Mustapha El Hamdaoui, Rafael Grytz, Qiang Ding, A Brent Carter
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241323 (2020)
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease with a high morbidity and mortality. Some of the mechanisms of fibrosis development have been described using rodent models; however, the relevance of findings in these a
Externí odkaz:
https://doaj.org/article/e3fb8d8837b248ca9244bbbce1ac8b27
Publikováno v:
Toxins, Vol 13, Iss 11, p 776 (2021)
Pseudomonas (P.) aeruginosa is an opportunistic pathogen that causes serious infections and hospital-acquired pneumonia in immunocompromised patients. P. aeruginosa accounts for up to 20% of all cases of hospital-acquired pneumonia, with an attributa
Externí odkaz:
https://doaj.org/article/1626237b927449d69dacde3be9a92005
Autor:
Xue-Ke Zhao, Lei Yu, Ming-Liang Cheng, Pulin Che, Yin-Ying Lu, Quan Zhang, Mao Mu, Hong Li, Li-Li Zhu, Juan-Juan Zhu, Meng Hu, Po Li, Yue-Dong Liang, Xin-Hua Luo, Yi-Ju Cheng, Zhi-Xiang Xu, Qiang Ding
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Understanding the underlying molecular mechanisms of liver fibrosis is important to develop effective therapy. Herein, we show that focal-adhesion-kinse (FAK) plays a key role in promoting hepatic stellate cells (HSCs) activation in vitro an
Externí odkaz:
https://doaj.org/article/0be84a8d4f6043a6b8939f2069666e82
Autor:
Huiying Wu, Christopher Cottingham, Liping Chen, Hongxia Wang, Pulin Che, Kexiang Liu, Qin Wang
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180638 (2017)
Affective disorders impact nearly 10% of the adult population in the United States in a given year. Synaptic dysfunction has recently emerged as a key neurobiological mechanism underlying affective disorders such as anxiety and depression. In this st
Externí odkaz:
https://doaj.org/article/c5a9ace8e3de4f949ee64ce661660907
Autor:
Xue-Ke Zhao, Pulin Che, Ming-Liang Cheng, Quan Zhang, Mao Mu, Hong Li, Yuan Luo, Yue-Dong Liang, Xin-Hua Luo, Chang-Qing Gao, Patricia L Jackson, J Michael Wells, Yong Zhou, Meng Hu, Guoqiang Cai, Victor J Thannickal, Chad Steele, J Edwin Blalock, Xiaosi Han, Ching-Yi Chen, Qiang Ding
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167451 (2016)
Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory mediator and its expression is up-regulated in chronic obstructive pulmonary disease (COPD). Tristetraprolin (TTP) is implicated in regulation of TNF-α expression; however, whether TT
Externí odkaz:
https://doaj.org/article/f6e719c7215c425cbbbf0b028f485380
Autor:
Pulin Che, Yunjia Chen, Roujian Lu, Ning Peng, Mary Gannon, J Michael Wyss, Kai Jiao, Qin Wang
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135030 (2015)
The α2 adrenergic receptor (AR) subtypes are important for blood pressure control. When activated, the α2A subtype elicits a hypotensive response whereas the α2B subtype mediates a hypertensive effect that counteracts the hypotensive response by t
Externí odkaz:
https://doaj.org/article/c6d3d5b6f2f54afc85b8dcdeff93c56d
Autor:
Rui-Han Hu, Mustapha El Hamdaoui, Pulin Che, Xueke Zhao, Rafael Grytz, Yiju Cheng, Qiang Ding, Meimei Wang, A. Brent Carter, Jennifer L. Larson-Casey
Publikováno v:
Laboratory Investigation. 101:116-124
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease without effective therapy. Animal models effectively reproducing IPF disease features are needed to study the underlying molecular mechanisms. Tree shrews are genetically, ana
Publikováno v:
Toxins
Pseudomonas (P.) aeruginosa is an opportunistic pathogen that causes serious infections and hospital-acquired pneumonia in immunocompromised patients. P. aeruginosa accounts for up to 20% of all cases of hospital-acquired pneumonia, with an attributa
Autor:
Meng Hu, Liyong Wu, Xiaosi Han, Yuping Wang, Karyn Ding, Qiang Ding, Zhaoyang Huang, Pulin Che, Yan Ding, Xueke Zhao, Ning Li, Jianghong Liu, Lynn Han, Shuqin Zhan, Spring Li
Publikováno v:
Journal of Cellular and Molecular Medicine
Hypocretin 1 and hypocretin 2 (orexin A and B) regulate sleep, wakefulness and emotion. Tumour necrosis factor alpha (TNF‐α) is an important neuroinflammation mediator. Here, we examined the effects of TNF‐α treatment on hypocretin expression i
Autor:
Wenbin Zhang, Huafeng Wang, Xiaoxue Ke, Qiang Ding, Xiaosi Han, Gregory K. Friedman, Pulin Che, Burt Nabors, Meimei Wang, Lei Yu
Publikováno v:
Cancers
Volume 13
Issue 5
Cancers, Vol 13, Iss 1111, p 1111 (2021)
Volume 13
Issue 5
Cancers, Vol 13, Iss 1111, p 1111 (2021)
Simple Summary Interactions of integrins with the extracellular matrix play a key role in cancer cell migration, invasion, and growth. However, whether integrin engagement promotes cancer progression through metabolic reprogramming has not been compl