Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pulicat S. Manogaran"'
Autor:
Hindi Al-Hindi, Abeer Al-Amr, Ali S. Alzahrani, Avaniyapuram Kannan Murugan, Pulicat S Manogaran, Mysoon M. Al-Ansari
Publikováno v:
Endocrine-Related Cancer. 28:273-289
Thyroid cancer is a common endocrine neoplasm. Despite its good prognosis, it can lead to significant morbidity and mortality due to metastasis and recurrence. However, the factors involved in metastasis are not well studied. Therefore, we selected m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14a9da9b3cb64762bc24ecce1b15b2c
https://doi.org/10.1530/erc-20-0242
https://doi.org/10.1530/erc-20-0242
Autor:
Saeeda O. Ahmed, Khawla S. Al-Kuraya, Maqbool Ahmed, Leonidas C. Platanias, Pulicat S. Manogaran, Shahab Uddin, Syed N. Alvi, Azhar R. Hussain
Publikováno v:
Free Radical Biology and Medicine. 50:978-987
We provide evidence that thymoquinone (TQ), a natural compound isolated from Nigella sativa, induces growth inhibition and apoptosis in several primary effusion lymphoma (PEL) cell lines. Our data demonstrate that TQ treatment results in down-regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce9b2f56f4cddabe2e8f8681ce91a98
https://doi.org/10.1016/j.freeradbiomed.2010.12.034
https://doi.org/10.1016/j.freeradbiomed.2010.12.034
Autor:
Khawla S. Al-Kuraya, Naif A. Al-Jomah, Shahab Uddin, Mehar Sultana, Pulicat S. Manogaran, Asma S. Khan, M Ahmed, Leonidas C. Platanias, Azhar R. Hussain, Jehad Abubaker
Publikováno v:
Molecular Cancer Therapeutics. 7:3318-3329
We provide evidence that curcumin, a natural compound isolated from rhizomes of plant Curcuma longa, induces apoptosis in several Burkitt's lymphoma cell lines expressing Bax protein (AS283A, KK124, and Pa682PB), whereas it has no effects in cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c5095982b47b94275d0f70a3377fbd
https://doi.org/10.1158/1535-7163.mct-08-0541
https://doi.org/10.1158/1535-7163.mct-08-0541
Autor:
Khaled Al-Hussein, Salman A. H. Alrokayan, Abdelilah Aboussekhra, Pulicat S. Manogaran, Zakia Shinwari
Publikováno v:
Journal of Neuro-Oncology. 87:123-132
Medulloblastomas arise in the cerebellum and are the most common pediatric primary malignant brain tumors. Currently, medulloblastoma patients are best treated with surgical removal of the tumor, adjuvant radiation therapy and chemotherapy. The chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3e96c9badc72e8a1a1eadb2517aeb4
https://doi.org/10.1007/s11060-007-9502-4
https://doi.org/10.1007/s11060-007-9502-4
Autor:
Pulicat S. Manogaran, Khalid Al-Hussein, Azhar R. Hussain, Khawla S. Al-Kuraya, Leonidas C. Platanias, Jehad Abubaker, Shahab Uddin, Abdul K. Siraj, Naif A. Al-Jomah
Publikováno v:
Cancer Research. 67:3888-3897
Primary effusion lymphoma (PEL) is an incurable, aggressive B-cell malignancy that develops rapid resistance to conventional chemotherapy. In efforts to identify novel approaches to block proliferation of PEL cells, we found that sanguinarine, a natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40ae61cf131332432928d8ebbd9c7bf
https://doi.org/10.1158/0008-5472.can-06-3764
https://doi.org/10.1158/0008-5472.can-06-3764
Autor:
Basem Al-Otaibi, Ibtehaj S. Al-Sharif, Amal Al-Haza'a, Khairia M. Youssef, Ensaf M Al-Hujaily, Ibrahim Al-Jammaz, Ameera Gaafar Mohamed, Khaled Al-Hussein, Pulicat S. Manogaran, Abdelilah Aboussekhra
Publikováno v:
Breast cancer research and treatment. 128(1)
We have investigated here the anti-breast cancer properties of two novel curcumin analogues, EAC and PAC. Apoptosis was assessed by the annexin V/propidium iodide (PI) assay on different breast cancer and normal cells. Immunoblotting analysis determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6e6a415f2b7f75f14a38baaf14c804
https://pubmed.ncbi.nlm.nih.gov/20680677
https://pubmed.ncbi.nlm.nih.gov/20680677
Autor:
Alia Iqniebi, Ameera Gaafar, Hazaa Alzahrani, Khalid Al-Hussein, Adher Al-Sayed, Abdullah Al-Sulaiman, Pulicat S. Manogaran, Gamal Eldin H. Mohamed, Fahad Al Mohareb, Dahish Ajarim, Abdelghani Tabakhi, Fahad Alsharif, Mahmoud Aljurf
Publikováno v:
Experimental hematology. 37(7)
The purpose of this study was to examine the antitumor immune function of gammadelta T cells and to scan the granzyme B gene for the known single nucleotide polymorphism in breast cancer patients and normal controls.Levels, cytotoxicity, and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721285d751ed630aec817d97cb01e5e2
https://pubmed.ncbi.nlm.nih.gov/19446661
https://pubmed.ncbi.nlm.nih.gov/19446661
Autor:
Azadali Moorji, Naif A. Al-Jomah, Fouad Al-Dayel, Shahab Uddin, Hassan El-Solh, Adnan Ezzat, Asim F. Belgaumi, Valerie L. Atizado, Azhar R. Hussain, Khawla S. Al-Kuraya, Prashant Bavi, Abdul K. Siraj, Pulicat S. Manogaran
Publikováno v:
Blood. 108(13)
Phosphatidylinositol 3′-kinase (PI3K) is a key player in cell-growth signaling in a number of lymphoid malignancies, but its role in diffuse large B-cell lymphoma (DLBCL) has not been fully elucidated. Therefore, we investigated the role of the PI3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224fe18e0184ab3cc9c3b62295339806
https://pubmed.ncbi.nlm.nih.gov/16946303
https://pubmed.ncbi.nlm.nih.gov/16946303
Autor:
Shahab Uddin, Pulicat S. Manogaran, Azhar R. Hussain, Leonidas C. Platanias, Maha Al-Rasheed, K. Al Kuraya, Khalid Al-Hussein
Publikováno v:
Apoptosis : an international journal on programmed cell death. 11(2)
Curcumin has been shown to possess variety of biological functions including anti-tumor activity. The mechanism by which curcumin inhibit cell proliferation remains poorly understood. In the present report, we investigated the effect of curcumin on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d4ad5ac3a0eefa0eeaa5bc7a8bf556
https://pubmed.ncbi.nlm.nih.gov/16502262
https://pubmed.ncbi.nlm.nih.gov/16502262
Autor:
Pulicat S. Manogaran, Khaled Al-Hussein, Kishor Bhatia, Shahab Uddin, Azhar R. Hussain, Marina I. Gutiérrez, Leonidas C. Platanias
Publikováno v:
Oncogene. 24(47)
The mechanisms that regulate induction of the antiapoptotic state and mitogenic signals in primary effusion lymphoma (PEL) are not well known. In efforts to identify novel approaches to block the proliferation of PEL cells, we found that curcumin (di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652bc86053f88a691b40c0320ef8fe5f
https://pubmed.ncbi.nlm.nih.gov/16044161
https://pubmed.ncbi.nlm.nih.gov/16044161