Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pule Seboletswe"'
Autor:
Nosipho Cele, Paul Awolade, Pule Seboletswe, Lungisani Khubone, Kolawole Olofinsan, Md. Shahidul Islam, Audrey Jordaan, Digby F. Warner, Parvesh Singh
Publikováno v:
ChemistryOpen, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Two libraries of quinoline‐based hybrids 1‐(7‐chloroquinolin‐4‐yl)‐1H‐pyrazolo[3,4–d]pyrimidin‐4‐amine and 7‐chloro‐N‐phenylquinolin‐4‐amine were synthesized and evaluated for their α‐glucosidase inhibitory a
Externí odkaz:
https://doaj.org/article/8d47b8ac9082410195c81e8781270c6f
Autor:
Shekhar, Matthéo Alcaraz, Pule Seboletswe, Neha Manhas, Laurent Kremer, Parvesh Singh, Vipan Kumar
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e22182- (2023)
A series of triclosan azo-adducts were synthesized to investigate their structure-activity relationship against Mycobacterium tuberculosis and non-tuberculous mycobacteria. The series' most potent compound was four and sixteen times more active than
Externí odkaz:
https://doaj.org/article/33012e2b7a5c4e46b4227dbf77e0c8ec
Autor:
Nosipho Cele, Paul Awolade, Pule Seboletswe, Kolawole Olofinsan, Md. Shahidul Islam, Parvesh Singh
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 1035 (2022)
Diabetes mellitus (DM) is a multifaceted metabolic disorder that remains a major threat to global health security. Sadly, the clinical relevance of available drugs is burdened with an upsurge in adverse effects; hence, inhibiting the carbohydrate-hyd
Externí odkaz:
https://doaj.org/article/8a1671b8232149f7a2337a18b6f3aeac
Autor:
Muhammad D. Bala, Naresh Kumar Katari, Baji Baba Shaik, Pule Seboletswe, Rambabu Gundla, Narva Deshwar Kushwaha, Vishal Kumar, Parvesh Singh, Rajshekhar Karpoormath
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 23:142-163
Cancer is considered one of the leading causes of death globally, especially patients with lung, pancreatic, or brain tumors are most likely to die of cancer, and patients with prostate and breast cancer are at a high risk of noncancer death. As a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f324f40ac3d5ea42831cefcb600aecb
https://doi.org/10.2174/1871520622666220418143438
https://doi.org/10.2174/1871520622666220418143438
Autor:
Shefali Chowdhary, null Shalini, Joel Mosnier, Isabelle Fonta, Bruno Pradines, Nosipho Cele, Pule Seboletswe, Parvesh Singh, Vipan Kumar
Publikováno v:
ACS Medicinal Chemistry Letters
ACS Medicinal Chemistry Letters, 2022, 13 (7), pp.1068-1076. ⟨10.1021/acsmedchemlett.2c00078⟩
ACS Medicinal Chemistry Letters, 2022, 13 (7), pp.1068-1076. ⟨10.1021/acsmedchemlett.2c00078⟩
In the search of new antiplasmodial agents, a multitargeted approach was used in the synthesis of triazolopyrimidine- and 4-aminoquinolines-based hybrids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafdddc892d5832224fa541ef313502e
https://pubmed.ncbi.nlm.nih.gov/35859870
https://pubmed.ncbi.nlm.nih.gov/35859870
Publikováno v:
ChemMedChem. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7f844cdebefc7e52b140bc9deab302b
https://doi.org/10.1002/cmdc.202200618
https://doi.org/10.1002/cmdc.202200618
Autor:
Mamoalosi A. Selepe, Phaladi Kunyane, Pule Seboletswe, Shankari Nair, Nosipho Cele, Monique Engelbrecht, Daniël F. Joubert, Charlot Vandevoorde, Parvesh Singh, Molahlehi S. Sonopo
Publikováno v:
Bioorganic chemistry. 128
Isoflavone derivatives were prepared from benzoylbenzofuran precursors. The synthesized compounds were analyzed by 1D and 2D nuclear magnetic resonance (NMR) spectroscopy, as well as high-resolution mass spectrometry (HRMS) to confirm their structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4451661adb0860a620f1b6f900cb0727
https://pubmed.ncbi.nlm.nih.gov/35998518
https://pubmed.ncbi.nlm.nih.gov/35998518
Autor:
Shefali Chowdhary, Asif Raza, Pule Seboletswe, Nosipho Cele, Arun K. Sharma, Parvesh Singh, Vipan Kumar
Publikováno v:
Journal of Molecular Structure. 1275:134627
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6c5882a21466ad20d6c8713bcb636f6
https://doi.org/10.1016/j.molstruc.2022.134627
https://doi.org/10.1016/j.molstruc.2022.134627
Publikováno v:
ChemMedChem. 16(13)
Heterocyclic compounds constitute a unique class of organic compounds endowed with a wide range of synthetic and pharmaceutical applications. Pyrimidinones and their fused analogues have received focused attention in this regard, partly due to their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba64d86b3b6c0f6fdfc8b0b8d729b66a
https://pubmed.ncbi.nlm.nih.gov/33724717
https://pubmed.ncbi.nlm.nih.gov/33724717