Decreased DNA density is a better indicator of a nuclear bleb than lamin B loss.

Autor: Bunner S; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Prince K; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA.; Molecular and Cellular Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA., Pujadas Liwag EM; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.; IBIS Interdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston, IL 60208, USA., Eskndir N; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Srikrishna K; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., McCarthy AA; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Kuklinski A; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Jackson O; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Pellegrino P; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Jagtap S; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Eweka I; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Lawlor C; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Eastin E; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Yas G; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Aiello J; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., LaPointe N; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., von Blucher IS; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Hardy J; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Chen J; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Figueroa S; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Backman V; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Janssen A; School of Biological Sciences, University of Cambridge, Cambridge, UK., Packard M; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Dorfman K; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA., Almassalha L; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Seifu Bahiru M; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA.; Program in Neuroscience and Behavior, University of Massachusetts, Amherst, MA 01003, USA., Stephens AD; Biology Department, University of Massachusetts Amherst, Amherst, MA. 01003, USA.; Molecular and Cellular Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA.

Publikováno v: Journal of cell science [J Cell Sci] 2024 Nov 06. Date of Electronic Publication: 2024 Nov 06.

Local Volume Concentration, Packing Domains and Scaling Properties of Chromatin.

Autor: Carignano M; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Kröger M; Magnetism and Interface Physics & Computational Polymer Physics, Department of Materials, ETH Zurich, CH-8093 Zurich, Switzerland., Almassalha LM; Department of Gastroenterology and Hepatology, Northwestern Memorial Hospital, Chicago IL 60611, USA., Agrawal V; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Li WS; Applied Physics Program, Northwestern, University, Evanston, IL 60208, USA., Pujadas-Liwag EM; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Nap RJ; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Backman V; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Szleifer I; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.; Department of Chemistry, Northwestern University, Evanston, IL 60208, USA.

Publikováno v: ArXiv [ArXiv] 2024 Jun 13. Date of Electronic Publication: 2024 Jun 13.

Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism.

Autor: Pujadas Liwag EM; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.; IBIS Interdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston, USA.; Center for Physical Genomics and Engineering, Northwestern University, Evanston, IL, 60208, USA., Wei X; Department of Surgery, University of Virginia School of Medicine, Charlottesville, VA, 22903, USA., Acosta N; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.; Center for Physical Genomics and Engineering, Northwestern University, Evanston, IL, 60208, USA., Carter LM; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.; IBIS Interdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston, USA.; Center for Physical Genomics and Engineering, Northwestern University, Evanston, IL, 60208, USA., Yang J; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Almassalha LM; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.; Center for Physical Genomics and Engineering, Northwestern University, Evanston, IL, 60208, USA.; Department of Gastroenterology and Hepatology, Northwestern Memorial Hospital, Chicago, IL, 60611, USA., Jain S; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.; Center for Physical Genomics and Engineering, Northwestern University, Evanston, IL, 60208, USA., Daneshkhah A; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.; Center for Physical Genomics and Engineering, Northwestern University, Evanston, IL, 60208, USA., Rao SSP; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX, 77030, USA.; School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Seker-Polat F; Feinberg School of Medicine, Robert Lurie Comprehensive Cancer Center, Department of Obstetrics and Gynecology, Northwestern University, Chicago, IL, 60611, USA., MacQuarrie KL; Feinberg School of Medicine, Robert Lurie Comprehensive Cancer Center, Department of Pediatrics, Northwestern University, Chicago, IL, 60611, USA.; Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Ibarra J; Feinberg School of Medicine, Robert Lurie Comprehensive Cancer Center, Department of Pediatrics, Northwestern University, Chicago, IL, 60611, USA.; Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Agrawal V; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.; Center for Physical Genomics and Engineering, Northwestern University, Evanston, IL, 60208, USA., Aiden EL; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX, 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.; Center for Theoretical Biological Physics, Rice University, Houston, TX, 77030, USA.; Departments of Computer Science and Computational and Applied Mathematics, Rice University, Houston, TX, 77030, USA., Kanemaki MT; Department of Chromosome Science, National Institute of Genetics, Mishima, Shizuoka, 411-8540, Japan.; Graduate Institute for Advanced Studies, SOKENDAI, Mishima, Shizuoka, 411-8540, Japan.; Department of Biological Science, The University of Tokyo, Tokyo, 113-0033, Japan., Backman V; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA. v-backman@northwestern.edu.; Center for Physical Genomics and Engineering, Northwestern University, Evanston, IL, 60208, USA. v-backman@northwestern.edu., Adli M; Feinberg School of Medicine, Robert Lurie Comprehensive Cancer Center, Department of Obstetrics and Gynecology, Northwestern University, Chicago, IL, 60611, USA. adli@northwestern.edu.

Publikováno v: Genome biology [Genome Biol] 2024 Mar 22; Vol. 25 (1), pp. 77. Date of Electronic Publication: 2024 Mar 22.