NOTCH1 mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle G1/S transition and specific cyclin overexpression. Preclinical ground for targeted inhibition

Autor: Carrillo-Tornel, Salvador, Chen-Liang, Tzu Hua, Zurdo, María, Puiggros Metje, Anna Maria, Gómez-Llonín, Andrea, García-Malo, María Dolores, Cuenca-Zamora, Ernesto José, Ortuño, Francisco José, Hurtado López, Ana María, Espinet Solà, Blanca, Jerez, Andrés

[AHEAD] Data de publicació electrónica: 27-12-2022 Studies prior to next-generation sequencing (NGS) showed that the frequent indolent course of chronic lymphocytic leukaemia (CLL) is related to most cells remaining quiescent in the G0 -G1 cell cyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1610::dd9727f8779e9ae977a83c881c248442
http://hdl.handle.net/10230/55947

Development and validation of a sequencing panel for translocations, copy number alterations and mutations with clinical relevance in mature B-cell neoplasms

Autor: Gómez Llonin, Andrea

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
Universitat Autònoma de Barcelona

[eng] The application of NGS techniques to the study of mature B-cell neoplasms at the research level is providing a large amount of new information, in certain cases with clinical implications, which includes the identification of molecular biomarke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::35aa98d8a8208604591fc1c732b66ef8
http://hdl.handle.net/10803/673450