Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Pui-San Wong"'
Detection and characterization of a novel marine birnavirus isolated from Asian seabass in Singapore
Autor:
Jing Chen, Xinyu Toh, Jasmine Ong, Yahui Wang, Xuan-Hui Teo, Bernett Lee, Pui-San Wong, Denyse Khor, Shin-Min Chong, Diana Chee, Alvin Wee, Yifan Wang, Mee-Keun Ng, Boon-Huan Tan, Taoqi Huangfu
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-10 (2019)
Abstract Background Lates calcarifer, known as seabass in Asia and barramundi in Australia, is a widely farmed species internationally and in Southeast Asia and any disease outbreak will have a great economic impact on the aquaculture industry. Throu
Externí odkaz:
https://doaj.org/article/5e72a8d9863b422b892dcebaa0def993
Publikováno v:
Viruses, Vol 10, Iss 12, p 692 (2018)
The poxviruses are large, linear, double-stranded DNA viruses about 130 to 230 kbp, that have an animal origin and evolved to infect a wide host range. Variola virus (VARV), the causative agent of smallpox, is a poxvirus that infects only humans, but
Externí odkaz:
https://doaj.org/article/4229f2c36db94a49bbcc2d75aaf6e3bf
Autor:
Agata Blasiak, Jhin Jieh Lim, Shirley Gek Kheng Seah, Theodore Kee, Alexandria Remus, De Hoe Chye, Pui San Wong, Lissa Hooi, Anh T. L. Truong, Nguyen Le, Conrad E. Z. Chan, Rishi Desai, Xianting Ding, Brendon J. Hanson, Edward Kai‐Hua Chow, Dean Ho
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 1, Pp n/a-n/a (2021)
Abstract The emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) led to multiple drug repurposing clinical trials that have yielded largely uncertain outcomes. To overcome this challenge, we used IDentif.AI, a platform that
Externí odkaz:
https://doaj.org/article/3bdb703644b14f66b5677f820eca6cec
Autor:
Conrad E Z Chan, Shirley G K Seah, De Hoe Chye, Shane Massey, Maricela Torres, Angeline P C Lim, Steven K K Wong, Jacklyn J Y Neo, Pui San Wong, Jie Hui Lim, Gary S L Loh, Dongling Wang, Jerome D Boyd-Kirkup, Siyu Guan, Dipti Thakkar, Guo Hui Teo, Kiren Purushotorman, Paul E Hutchinson, Barnaby E Young, Jenny G Low, Paul A MacAry, Hannes Hentze, Venkateshan S Prativadibhayankara, Kantharaj Ethirajulu, Jason E Comer, Chien-Te K Tseng, Alan D T Barrett, Piers J Ingram, Trevor Brasel, Brendon John Hanson
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253487 (2021)
Although SARS-CoV-2-neutralizing antibodies are promising therapeutics against COVID-19, little is known about their mechanism(s) of action or effective dosing windows. We report the generation and development of SC31, a potent SARS-CoV-2 neutralizin
Externí odkaz:
https://doaj.org/article/98d0e9238a8f44f8a516de81e7cb9d0e
Autor:
Conrad En-Zuo Chan, Ching-Ging Ng, Angeline Pei-Chew Lim, Shirley Lay-Kheng Seah, De-Hoe Chye, Steven Ka-Khuen Wong, Jie-Hui Lim, Vanessa Zi-Yun Lim, Soak-Kuan Lai, Pui-San Wong, Kok-Mun Leong, Yi-Chun Liu, Richard J. Sugrue, Boon-Huan Tan
Publikováno v:
Journal of Virology. 96
A human monoclonal antibody panel (PD4, PD5, PD7, SC23, and SC29) was isolated from the B cells of convalescent patients and used to examine the S protein in SARS-CoV-2-infected cells. While all five antibodies bound conformational-specific epitopes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecf7e543845d9ae3806448ce0836308
https://doi.org/10.1128/jvi.00455-22
https://doi.org/10.1128/jvi.00455-22
Autor:
Conrad En-Zuo Chan, Ching-Ging Ng, Angeline Pei-Chew Lim, Shirley Lay-Kheng Seah, De-Hoe Chye, Steven Ka-Khuen Wong, Jie-Hui Lim, Vanessa Zi-Yun Lim, Soak-Kuan Lai, Pui-San Wong, Kok-Mun Leong, Yi-Chun Liu, Richard J Sugrue, Boon-Huan Tan
A human monoclonal antibody panel (PD4, PD5, PD7, SC23 and SC29) was isolated from the B cells of convalescent patients and used to examine the S protein in SARS-CoV-2- infected cells. While all five antibodies bound conformational-specific epitopes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ad3dd6e3be64a5f34854fc60afdecb
https://doi.org/10.1101/2021.12.06.471528
https://doi.org/10.1101/2021.12.06.471528
Autor:
Chien-Te K Tseng, Dipti Thakkar, Boyd-Kirkup Jerome Douglas, Trevor Brasel, Paul A. MacAry, Dong Ling Wang, Jason E. Comer, Hannes Hentze, Ingram Piers, Brendon J. Hanson, Angeline P.C. Lim, Guan Siyu, Maricela Torres, Kiren Purushotorman, Damian O’Connell, Jacklyn J.Y. Neo, Guo Hui Teo, Steven K.K. Wong, Conrad E.Z. Chan, Shirley Gek Kheng Seah, Venkateshan S. Prativadibhayankara, Paul Edward Hutchinson, De Hoe Chye, Jenny G. Low, Gary S.L. Loh, Kantharaj Ethirajulu, David C. Lye, Jie Hui Lim, Pui San Wong, Barnaby Edward Young, Alan D.T. Barrett, Shane Massey
SARS-CoV-2-neutralizing antibodies are promising therapeutics for COVID-19. However, little is known about the mechanisms of action of these antibodies or their effective dosing windows. We report the discovery and development of SC31, a potent SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::606850ac3cb09b13cecd9961dbe2c00e
https://doi.org/10.1101/2020.10.26.355107
https://doi.org/10.1101/2020.10.26.355107
Autor:
Conrad Chan, Lissa Hooi, Anh T. L. Truong, De Hoe Chye, Theodore Kee, Alexandria Remus, Jhin Jieh Lim, Brendon John Hanson, Dean Ho, Agata Blasiak, Edward Kai-Hua Chow, Nguyen Le, Shirley Gek Kheng Seah, Rishi J. Desai, Xianting Ding, Pui San Wong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ef8d19f25241f8120e33ad936b2815
https://doi.org/10.1002/btm2.10196/v2/response1
https://doi.org/10.1002/btm2.10196/v2/response1
Publikováno v:
EDULEARN Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25419a53512b6ee9ece3566bfdaed73e
https://doi.org/10.21125/edulearn.2020.1196
https://doi.org/10.21125/edulearn.2020.1196
Autor:
Edward Kai-Hua Chow, Theodore Kee, De Hoe Chye, Lissa Hooi, Dean Ho, Nguyen Le, Shirley Gek Kheng Seah, Xianting Ding, Rishi J. Desai, Pui San Wong, Alexandria Remus, Brendon J. Hanson, Jhin Jieh Lim, Agata Blasiak, Anh T. L. Truong, Conrad E.Z. Chan
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19) has led to the rapid initiation of urgently needed clinical trials of repurposed drug combinations and monotherapies. These regimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2567ef110059affc2d73c8007fff9239
https://doi.org/10.1101/2020.05.04.20088104
https://doi.org/10.1101/2020.05.04.20088104