Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Pui-Chun Chan"'
Autor:
Ruiqi Zhang, Ka-Yi Leung, Danlei Liu, Yujing Fan, Lu Lu, Pui-Chun Chan, Kelvin Kai-Wang To, Honglin Chen, Kwok-Yung Yuen, Kwok-Hung Chan, Ivan Fan-Ngai Hung
Publikováno v:
mSphere, Vol 7, Iss 2 (2022)
ABSTRACT COVID-19 infection is a global health issue, and vaccination is the main strategy to control this pandemic. In this study, 189 participants received BNT162b2 or CoronaVac vaccine, and 133 of them recorded adverse events (AEs) daily for 4 wee
Externí odkaz:
https://doaj.org/article/53848044952f4e558681998bfc0c0259
Autor:
Ka-Wa Khong, Danlei Liu, Ka-Yi Leung, Lu Lu, Hoi-Yan Lam, Linlei Chen, Pui-Chun Chan, Ho-Ming Lam, Xiaochun Xie, Ruiqi Zhang, Yujing Fan, Kelvin Kai-Wang To, Honglin Chen, Kwok-Yung Yuen, Kwok-Hung Chan, Ivan Fan-Ngai Hung
Publikováno v:
Vaccines, Vol 10, Iss 2, p 160 (2022)
By vaccinating SARS-CoV-2 naïve individuals who have already received two doses of COVID-19 vaccines, we aimed to investigate whether a heterologous prime-boost strategy, using vaccines of different platforms as the booster dose, can enhance the imm
Externí odkaz:
https://doaj.org/article/e62461cb08ff438da94a660f9acbd621
Autor:
Ruiqi Zhang, Danlei Liu, Ka-Yi Leung, Yujing Fan, Lu Lu, Pui-Chun Chan, Kelvin Kai-Wang To, Honglin Chen, Kwok-Yung Yuen, Kwok-Hung Chan, Ivan Fan-Ngai Hung
Publikováno v:
Vaccines, Vol 10, Iss 1, p 72 (2022)
The emergence of SARS-CoV-2 variants may impact the effectiveness of vaccines, while heterologous vaccine strategy is considered to provide better protection. The immunogenicity of an mRNA-inactivated virus vaccine against the SARS-CoV-2 wild-type (W
Externí odkaz:
https://doaj.org/article/43fad75972cc424688a2a80b56226290
Autor:
Ruiqi Zhang, Ka-Wa Khong, Ka-Yi Leung, Danlei Liu, Yujing Fan, Lu Lu, Pui-Chun Chan, Linlei Chen, Kelvin Kai-Wang To, Honglin Chen, Kwok-Yung Yuen, Kwok-Hung Chan, Ivan Fan-Ngai Hung
Publikováno v:
Vaccines, Vol 9, Iss 12, p 1442 (2021)
Vaccinating recovered patients previously infected by COVID-19 with mRNA vaccines to boost their immune response against wild-type viruses (WT), we aimed to investigate whether vaccine platform and time of vaccination affect immunogenicity against th
Externí odkaz:
https://doaj.org/article/2c243a3ae05e49f5a520be51216fb7d8
Autor:
Jonathan Daniel Ip, Wing-Ming Chu, Wan-Mui Chan, Allen Wing-Ho Chu, Rhoda Cheuk-Ying Leung, Qi Peng, Anthony Raymond Tam, Brian Pui-Chun Chan, Jian-Piao Cai, Kwok-Yung Yuen, Kin-Hang Kok, Yi Shi, Ivan Fan-Ngai Hung, Kelvin Kai-Wang To
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105371- (2024)
Externí odkaz:
https://doaj.org/article/b522914c8c5943c495355d94e058e0b6
Autor:
Jonathan Daniel Ip, Wing-Ming Chu, Wan-Mui Chan, Allen Wing-Ho Chu, Rhoda Cheuk-Ying Leung, Qi Peng, Anthony Raymond Tam, Brian Pui-Chun Chan, Jian-Piao Cai, Kwok-Yung Yuen, Kin-Hang Kok, Yi Shi, Ivan Fan-Ngai Hung, Kelvin Kai-Wang To
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105273- (2024)
Summary: Background: De novo amino acid substitutions (DNS) frequently emerge among immunocompromised patients with chronic SARS-CoV-2 infection. While previous studies have reported these DNS, their significance has not been systematically studied.
Externí odkaz:
https://doaj.org/article/89e94789ce4f4b44920ae257a080861d
Autor:
Hoi-Wah Tsoi, Miko Ka-Wai Ng, Jian-Piao Cai, Rosana Wing-Shan Poon, Brian Pui-Chun Chan, Kwok-Hung Chan, Anthony Raymond Tam, Wing-Ming Chu, Ivan Fan-Ngai Hung, Kelvin Kai-Wang To
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35334- (2024)
The COVID-19 pandemic has had a major impact on global health and economy, which was significantly mitigated by the availability of COVID-19 vaccines. The levels of systemic and mucosal antibodies against SARS-CoV-2 correlated with protection. Howeve
Externí odkaz:
https://doaj.org/article/477b4d7d411c48f8a00cff826dd02256
Autor:
Xiaojuan Zhang, Stephanie Joy-Ann Lam, Jonathan Daniel Ip, Carol Ho-Yan Fong, Allen Wing-Ho Chu, Wan-Mui Chan, Yoyo Suet-Yiu Lai, Hoi-Wah Tsoi, Brian Pui-Chun Chan, Lin-Lei Chen, Xinjie Meng, Shuofeng Yuan, Hanjun Zhao, Vincent Chi-Chung Cheng, Jacqueline Kwan Yuk Yuen, Kwok-Yung Yuen, Jie Zhou, Kelvin Kai-Wang To
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109706- (2024)
Summary: SARS-CoV-2 Omicron variant has evolved into sublineages. Here, we compared the neutralization susceptibility and viral fitness of EG.5.1 and XBB.1.9.1. Serum neutralization antibody titer against EG.5.1 was 1.71-fold lower than that for XBB.
Externí odkaz:
https://doaj.org/article/408891a80f1f40e78aaa030c09782216
Autor:
Desmond Yat-Hin Yap, Carol Ho-Yan Fong, Xiaojuan Zhang, Jonathan Daniel Ip, Wan-Mui Chan, Allen Wing-Ho Chu, Lin-Lei Chen, Yan Zhao, Brian Pui-Chun Chan, Kristine Shik Luk, Vincent Chi-Chung Cheng, Tak-Mao Chan, Kelvin Kai-Wang To
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Chronic kidney disease (CKD) patients are at higher risk of severe COVID-19. Humoral and cellular immunity from prior infection or vaccination are important for protection, but the neutralizing antibody (nAb) response against SARS-CoV-2 vari
Externí odkaz:
https://doaj.org/article/65a4fc7343c04329a778daf9e06c2afe
Autor:
Carol Ho-Yan Fong, Xiaojuan Zhang, Lin-Lei Chen, Rosana Wing-Shan Poon, Brian Pui-Chun Chan, Yan Zhao, Carlos King-Ho Wong, Kwok-Hung Chan, Kwok-Yung Yuen, Ivan Fan-Ngai Hung, Jacqueline Kwan Yuk Yuen, Kelvin Kai-Wang To
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104446- (2023)
Summary: Background: Vaccination reduces COVID-19-related hospitalization among older adults. However, how SARS-CoV-2 infection and vaccine regimens affect vaccine-elicited immunity remain unclear. Methods: This is a cross-sectional study recruiting
Externí odkaz:
https://doaj.org/article/414c3d0b747343d7b603d4c162a825c5