Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Pui‐Chi Lo"'
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Nanovaccines, a new generation of vaccines that use nanoparticles as carriers and/or adjuvants, have been widely used in the prevention and treatment of various diseases, including cancer. Nanovaccines have sparked considerable interest in c
Externí odkaz:
https://doaj.org/article/7005ec6983a641e29f8e54c18b6d45ca
Autor:
Lisen Lu, Huaduan Zi, Jie Zhou, Jing Huang, Zihan Deng, Zijian Tang, Li Li, Xiujuan Shi, Pui‐Chi Lo, Jonathan F. Lovell, Deqiang Deng, Chao Wan, Honglin Jin
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract Brain metastases (BRM) are common in advanced lung cancer. However, their treatment is challenging due to the blood‐brain barrier (BBB) and the immunosuppressive tumor microenvironment (ITME). Microparticles (MPs), a type of extracellular
Externí odkaz:
https://doaj.org/article/b8d0006b6ee9419fa13febdfd269bb9e
Autor:
Yan Hu, Yajie Sun, Chao Wan, Xiaomeng Dai, Shuhui Wu, Pui-Chi Lo, Jing Huang, Jonathan F. Lovell, Honglin Jin, Kunyu Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-28 (2022)
Abstract Extracellular vesicles (EVs), spherical biological vesicles, mainly contain nucleic acids, proteins, lipids and metabolites for biological information transfer between cells. Microparticles (MPs), a subtype of EVs, directly emerge from plasm
Externí odkaz:
https://doaj.org/article/ea32b58a76674e058840c17717c54332
Publikováno v:
Nano-Micro Letters, Vol 12, Iss 1, Pp 1-15 (2020)
Abstract In this study, a fucoidan-based theranostic nanogel (CFN-gel) consisting of a fucoidan backbone, redox-responsive cleavable linker and photosensitizer is developed to achieve activatable near-infrared fluorescence imaging of tumor sites and
Externí odkaz:
https://doaj.org/article/bb8bd3c5ee93404bb992974930c92cdb
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Cancer immunotherapy can boost the immune response of patients to eliminate tumor cells and suppress tumor metastasis and recurrence. However, immunotherapy resistance and the occurrence of severe immune-related adverse effects are clinical challenge
Externí odkaz:
https://doaj.org/article/d39f7fc99fd548f3a92400ddbdf7a7c8
Autor:
Priyanga Dharmaratne, Roy C. H. Wong, Jun Wang, Pui-Chi Lo, Baiyan Wang, Ben C. L. Chan, Kit-Man Lau, Clara B. S. Lau, Kwok-Pui Fung, Margaret Ip, Dennis K. P. Ng
Publikováno v:
Biomedicines, Vol 8, Iss 6, p 140 (2020)
A series of cationic boron dipyrromethene (BODIPY) derivatives were synthesized and characterized with various spectroscopic methods. Having the ability to generate singlet oxygen upon irradiation, these compounds could potentially serve as photosens
Externí odkaz:
https://doaj.org/article/8d2e1a58720042929ab6195c7dca3a1a
Magnetic Particle Imaging: From Tracer Design to Biomedical Applications in Vasculature Abnormality.
Autor:
Xulin Xie, Jiao Zhai, Xiaoyu Zhou, Zhengjun Guo, Pui-Chi Lo, Guangyu Zhu, Chan, Kannie W. Y., Mengsu Yang
Publikováno v:
Advanced Materials; 4/25/2024, Vol. 36 Issue 17, p1-43, 43p
Publikováno v:
Acta Biomaterialia. 162:57-71
Autor:
Leo K. B. Tam, Jacky C. H. Chu, Lin He, Caixia Yang, Kam-Chu Han, Peter Chi Keung Cheung, Dennis K. P. Ng, Pui-Chi Lo
Publikováno v:
Journal of the American Chemical Society. 145:7361-7375
Publikováno v:
Journal of Controlled Release. 353:663-674
We report herein a versatile and efficient bioorthogonal strategy to actualise targeted delivery and site-specific activation of photosensitisers for precise antitumoural photodynamic therapy. The strategy involved the use of an isonitrile-caged dist