Výsledky vyhledávání - "Pugazenthi A"

Akademický článek

Sall4 and Gata4 induce cardiac fibroblast transition towards a partially multipotent state with cardiogenic potential

Autor: Hong Gao, Saliha Pathan, Beverly R. E. A. Dixon, Aarthi Pugazenthi, Megumi Mathison, Tamer M.A. Mohamed, Todd K. Rosengart, Jianchang Yang

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Abstract Cardiac cellular fate transition holds remarkable promise for the treatment of ischemic heart disease. We report that overexpressing two transcription factors, Sall4 and Gata4, which play distinct and overlapping roles in both pluripotent st

Externí odkaz: https://doaj.org/article/dddb22f9f6054e26a9612826b2a513e0

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Akademický článek

Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Abstract Vestibular schwannomas (VS) are benign tumors that lead to significant neurologic and otologic morbidity. How VS heterogeneity and the tumor microenvironment (TME) contribute to VS pathogenesis remains poorly understood. In this study, we pe

Externí odkaz: https://doaj.org/article/04db7437a9cc4724883e4e3f2bf21c43

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Akademický článek

Activation of a GPCR, ORL1 Receptor: A Novel Therapy to Prevent Heart Failure Progression

Autor: Saliha S. Pathan, Aarthi Pugazenthi, Beverly R. E. A. Dixon, Theodore G. Wensel, Todd K. Rosengart, Megumi Mathison

Publikováno v: Journal of Cardiovascular Development and Disease, Vol 11, Iss 11, p 355 (2024)

The number of ischemic heart failure (HF) patients is growing dramatically worldwide. However, there are at present no preventive treatments for HF. Our previous study showed that Gata4 overexpression improved cardiac function after myocardial infarc

Externí odkaz: https://doaj.org/article/be5a8326140a4065aaf1f0c4db5dff10

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Akademický článek

Weather induced physiological responses on the flowering habits of neem trees (Azadirachta indica)

Autor: R. BALASREE, GA. DHEEBAKARAN, A. SENTHIL, N.K. SATHYAMOORTHY, PATIL SANTOSH GANAPATI, K. PUGAZENTHI

Publikováno v: Journal of Agrometeorology, Vol 26, Iss 2 (2024)

Adaptability and significant economic value of the neem tree are well-known, as it can flourish in a variety of environmental conditions. While the neem seed production is highly sensitive to prevailing weather conditions during the reproductive phas

Externí odkaz: https://doaj.org/article/938d5135bcd4499895f905b3b64a6b06

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