Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Puchun Liu"'
6
Pharmacokinetic and local tissue disposition of [14C]sodium diclofenac following iontophoresis and systemic administration in rabbits
Autor: Xiaoying Hui, Glen L. Xiong, Parminder Singh, Angela Anigbogu, Nicholas Poblete, Howard I. Maibach, Puchun Liu
Publikováno v: Journal of Pharmaceutical Sciences. 90:1269-1276
The systemic pharmacokinetics and local drug distribution of sodium diclofenac in skin and underlying tissues was studied. Iontophoresis facilitated local and systemic delivery of diclofenac sodium compared with passive diffusion. The maximum plasma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761f3a025fde5a1853575b5ff4da2fcc
https://doi.org/10.1002/jps.1079
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7
Transdermal iontophoretic delivery of methylphenidate HCl in vitro
Autor: Puchun Liu, Steven M. Dinh, Parminder Singh, Sophia Boniello
Publikováno v: International Journal of Pharmaceutics. 178:121-128
Methylphenidate is prescribed orally for Attention Deficit Disorder in children and adults, and for narcolepsy patients. Methylphenidate has a short plasma half-life (1-2 h) and thus needs to be frequently administered for effective therapy. Such the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359c4b88dfaf82faf80f42d8a2b7757d
https://doi.org/10.1016/s0378-5173(98)00358-5
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8
A protocol for the assessment of receiver solution additive-induced skin permeability changes. An example with γ-cyclodextrin
Autor: Puchun Liu, Jim Nightingale, Melinda G. Cettina, Erica Hansen, Joseph Sclafani
Publikováno v: International Journal of Pharmaceutics. 124:213-217
In the in vitro evaluation of transdermal drug delivery, the receiver solution composition can affect the experimental outcome. In particular, receiver solution accumulation of permeants having low aqueous solubility may give misleading results. Addi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0511b9489219c133f81a60dc801b9f5a
https://doi.org/10.1016/0378-5173(95)00091-v
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9
Enhanced transdermal delivery of estradiol in vitro using binary vehicles of isopropyl myristate and short-chain alkanols
Autor: Tamie Kurihara-Bergstrom, Melinda Goldberg-Cettina, James Alan Schriver Nightingale, Puchun Liu
Publikováno v: International Journal of Pharmaceutics. 114:237-245
The effect of binary vehicles of isopropyl myristate (IPM) and short-chain alkanols on the enhancement of skin permeation of estradiol (E 2 ) was studied in vitro using human epidermal membrane. The steady-state fluxes of E 2 and solvents across the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74538deb802f0bacc39acbf1bb5d173a
https://doi.org/10.1016/0378-5173(94)00253-2
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10
[Untitled]
Autor: William R. Good, William I. Higuchi, Puchun Liu, Abdel-Halim Ghanem
Publikováno v: Pharmaceutical Research. 11:1777-1784
This paper describes an experimental and theoretical evaluation of β-estradiol (E2) transport in post-surgery fresh human skin in vitro. Necessary auxiliary experimental methods were newly developed for these studies. The experimental fluxes of E2 a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65cafb5a01a7535b47cf5e5f85d57801
https://doi.org/10.1023/a:1018975602818
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