Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Puchit Samorapoompichit"'
Autor:
Karoline V. Gleixner, Matthias Mayerhofer, Karoline Sonneck, Alexander Gruze, Puchit Samorapoompichit, Christian Baumgartner, Francis Y. Lee, Karl J. Aichberger, Paul W. Manley, Doriano Fabbro, Winfried F. Pickl, Christian Sillaber, Peter Valent
Publikováno v:
Haematologica, Vol 92, Iss 11 (2007)
Background and Objectives In a majority of all patients with systemic mastocytosis (SM) including those with mast cell leukemia (MCL), neoplastic mast cells (MC) display the D816V-mutated variant of KIT. The respective oncoprotein, KIT D816V, exhibit
Externí odkaz:
https://doaj.org/article/430b7f84199e49c69294d2146859da51
Autor:
Gregor Hörmann, Puchit Samorapoompichit, Sabine Cerny-Reiterer, Michael Willmann, Gahininath Y. Bharate, Harald Herrmann, Thomas Rülicke, Michael Kneidinger, Barbara Peter, Peter Valent, Karoline V. Gleixner, Winfried F. Pickl, Katharina Blatt, W. R. Sperr, Hiroshi Maeda, Matthias Mayerhofer
Publikováno v:
Current Cancer Drug Targets. 12:51-63
Heat shock protein 32 (Hsp32), also known as heme oxygenase 1 (HO-1), has recently been identified as a potential target in various hematologic malignancies. We provide evidence that Hsp32 is constitutively expressed in primary leukemic cells in pati
Autor:
Keiryn L. Bennett, Winfried F. Pickl, Veronika Ferenc, Lily L. Remsing Rix, Christian Sillaber, Barbara Peter, Puchit Samorapoompichit, Harald Esterbauer, Christian Baumgartner, Alexander Gruze, Giulio Superti-Furga, Karoline V. Gleixner, Francis Y. Lee, Peter Valent
Publikováno v:
Experimental Hematology. 36:1244-1253
Objective Chronic eosinophilic leukemia (CEL) is a myeloproliferative disorder characterized by molecular and/or cytogenetic evidence of clonality of eosinophils, marked eosinophilia, and organ damage. In many patients, the transforming mutation FIP1
Autor:
Karoline V. Gleixner, Puchit Samorapoompichit, Christian Sillaber, Eva Jaeger, Hideaki Nakamura, Winfried F. Pickl, Khaled Greish, Gregor Hoermann, Harald Esterbauer, Julia Mayerhofer, Ilse Schwarzinger, Hiroshi Maeda, Karl J. Aichberger, Sophia Derdak, Rene G. Ott, Peter Valent, Veronika Sexl, Matthias Mayerhofer
Publikováno v:
Blood. 111:2200-2210
Resistance toward imatinib and other BCR/ABL tyrosine kinase inhibitors remains an increasing clinical problem in the treatment of advanced stages of chronic myeloid leukemia (CML). We recently have identified the heat shock protein 32 (Hsp32)/heme o
Autor:
Emir Hadzijusufovic, Matthias Mayerhofer, Puchit Samorapoompichit, Laura Rebuzzi, Karoline V. Gleixner, Alexander Gruze, Christian Sillaber, Karoline Sonneck, Vilma Yuzbasiyan-Gurkan, Winfried F. Pickl, Michael Willmann, Anja Vales, Michael Kneidinger, Tuddow Thaiwong, Peter Valent
Publikováno v:
Experimental Hematology. 35:1510-1521
Aggressive mast cell (MC) tumors are hematopoietic neoplasms characterized by uncontrolled growth of MC and resistance to conventional drugs. In most cases, the tyrosine kinase (TK) receptor KIT is involved in malignant cell growth. Therefore, severa
Autor:
Stefan Florian, Hermine Agis, Maria-T. Krauth, Puchit Samorapoompichit, Karoline Sonneck, Alexandra Böhm, Peter Valent, Wolfgang R. Sperr, Alexander W. Hauswirth
Publikováno v:
The Journal of Immunology. 176:1759-1768
High-dose cytosine arabinoside (HiDAC) and intermediate-dose cytosine arabinoside (IDAC) have been introduced as effective and safe consolidation chemotherapy in acute myeloid leukemia, with relatively low rates of life-threatening infections despite
Autor:
Friedrich Wimazal, W. R. Sperr, Maria Theresa Krauth, Puchit Samorapoompichit, Peter Valent, C. Worda, Gerit-Holger Schernthaner
Publikováno v:
Histopathology. 48:247-257
Aims : To analyse and characterize the ultrastructural morphology of normal tissue mast cells (MC) and neoplastic bone marrow MC. Methods : We have examined the ultrastructure and cytomorphological features of MC derived from cord blood cells, neopla
Autor:
Doriano Fabbro, Alexandra Böhm, Winfried F. Pickl, Karoline V. Gleixner, Karoline Sonneck, Peter Valent, Matthias Mayerhofer, Karl J. Aichberger, Christian Sillaber, Sophia Derdak, Paul W. Manley, Puchit Samorapoompichit, Alexander Gruze
Publikováno v:
Blood. 107:752-759
In most patients with systemic mastocytosis (SM), including aggressive SM and mast cell leukemia (MCL), neoplastic cells express the oncogenic KIT mutation D816V. KIT D816V is associated with constitutive tyrosine kinase (TK) activity and thus repres
Autor:
Puchit Samorapoompichit, Marianne Steiner, Peter Valent, Wolfgang R. Sperr, A Schedle, Franz Wachtler, Trevor Lucas
Publikováno v:
Leukemia & Lymphoma. 44:509-515
Mast cell leukemia (MCL) is a rare disorder characterized by rapid disease progression, resistance against conventional cytoreductive drugs, and short survival. In an attempt to identify drugs that show significant antiproliferative effects on neopla
Autor:
A Schedle, Xiaohui Rausch-Fan, R. Slavicek, Alexander Franz, Minoo Ghannadan, A. Ellinger, Walter Klepetko, Wolfgang Füreder, Puchit Samorapoompichit, Mehrdad Baghestanian, Wolfgang R. Sperr, W. Sperr, S Simak, Peter Valent
Publikováno v:
Journal of Biomedical Materials Research. 39:560-567
Recent data suggest that distinct metal ions can be released from dental alloys or other biomaterials, and may cause toxic effects on various cells. In this study, the effects of 14 metal ions on histamine release from human blood basophils (n = 4),