A case report of autoimmune GFAP astrocytopathy presenting with abnormal heart rate variability and blood pressure variability

Autor: Pu-yuan Wen, Guang-qiang Wang, Lian-wei Dou, Qi Chen, Xian-wen Chen, Li Gong

Publikováno v: BMC Neurology, Vol 23, Iss 1, Pp 1-6 (2023)

Abstract Background Autonomic dysfunctions including bladder dysfunction, gastrointestinal dysfunction and orthostasis are common symptoms of autoimmune glial fibrillary acidic protein astrocytopathy (A-GFAP-A); however, cardiac autonomic dysfunction

Externí odkaz: https://doaj.org/article/b075d2c5802b4962a9eb428bec3e9db6

Risk factors for the severity of Guillain-Barré syndrome and predictors of short-term prognosis of severe Guillain-Barré syndrome

Autor: Wenzheng Chu, Hong Liu, Li Gong, Lisha Wang, Pu-Yuan Wen, Hongliang Wu, Han Ji

Publikováno v: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Guillain-Barré syndrome (GBS) is a neurological disorder characterized by paralysis. Identifying the severity, appropriate therapeutic method, and prognosis of GBS at an early stage is highly important. This study aimed to investigate the modifiable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19c7e82d0c2aa8a9e756afe204009ea
https://doi.org/10.1038/s41598-021-91132-3

Tanshinone IIA increases levels of NeuN, protein disulfide isomerase, and Na+/K+-ATPase and decreases evidence of microglial activation after cerebral ischemic injury

Autor: Jian Li, Jie Liu, Bei-Ling Lu, Hao Luo, Pu-Yuan Wen, Jun Zhou, Wen-Wen Li, Feng-Zhen Yang, Li Zhou

Publikováno v: Neuroreport. 27(6)

This study was designed to clarify the neuroprotective effects of tanshinone IIA (TSA) following cerebral ischemic insult. Adult Sprague-Dawley rats were operated upon to achieve a middle cerebral artery occlusion to cause transient focal cerebral is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b131de421c914f25e8851fb623316d3c
https://pubmed.ncbi.nlm.nih.gov/26966780

Protective effect of Tanshinone IIA against infarct size and increased HMGB1, NFκB, GFAP and apoptosis consequent to transient middle cerebral artery occlusion

Autor: Stephen C. Bondy, Yu Hu, Pu-Yuan Wen, Zhi-Gang Ding, Fang Wang, Yun Tian, Jun Zhou, Wenwen Li, Li Zhou, Jian-gang Wang, Hao Luo, Feng-Zhen Yang

Publikováno v: Neurochemical research, vol 39, iss 2
Wang, JG; Bondy, SC; Zhou, L; Yang, FZ; Ding, ZG; Hu, Y; et al.(2014). Protective effect of tanshinone IIA against infarct size and increased HMGB1, NFκB, GFAP and apoptosis consequent to transient middle cerebral artery occlusion. Neurochemical Research, 39(2), 295-304. doi: 10.1007/s11064-013-1221-y. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/56w4322w

Acute inflammation plays an important role in brain damage following cerebral ischemia and reperfusion (I/R) injury. The present study employed a rat model of middle cerebral artery occlusion to explore the neuroprotective effects of tanshinone IIA (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8695b47e676d8c0ebead3077512aa5
https://escholarship.org/uc/item/56w4322w

[Nuclear factor κB and IKB expression and calcium deposition of atherosclerotic plaques in apolipoprotein E and low density lipoprotein receptor knockout mice]

Autor: Feng-zhen, Yang, Jun, Zhou, Wen-wen, Li, Fang, Wang, Pu-yuan, Wen, Li, Zhou, Jian-gang, Wang, Xing-xing, Zheng

Publikováno v: Zhonghua xin xue guan bing za zhi. 40(8)

To observe the histopathological features, nuclear factor-κB (NFκB) and IKB expressions as well as calcium deposition of atherosclerosis plaques (AS) in apolipoprotein E (ApoE) and low density lipoprotein receptor (LDLR) knockout mice (ApoE(-/-), L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0a1c7461d64a9fa9beca86ee093016a
https://pubmed.ncbi.nlm.nih.gov/23141015