Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Pu-Ting Xu"'
Autor:
Pu-Ting Xu, Yi-Ju Li, Xue-Jun Qin, Clemens R. Scherzer, Hong Xu, Donald E. Schmechel, Christine M. Hulette, John Ervin, Steven R. Gullans, Jonathan Haines, Margaret A. Pericak-Vance, John R. Gilbert
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 2, Pp 256-275 (2006)
Apolipoprotein E4 (APOE4) allele is a major risk factor for late-onset familial and sporadic Alzheimer disease (AD). The mechanism of action of APOE in the etiology of AD remains unclear. Using gene expression (microarray) analysis of human hippocamp
Externí odkaz:
https://doaj.org/article/fb575972e86c4999bd6dff46b2567152
Autor:
Pu-Ting Xu, Donald Schmechel, Hui-Ling Qiu, Michael Herbstreith, Tracie Rothrock-Christian, Michele Eyster, Allen D. Roses, John R. Gilbert
Publikováno v:
Neurobiology of Disease, Vol 6, Iss 1, Pp 63-75 (1999)
Mice transgenic for human APOE2, E3, and E4 alleles express native 34-kDa human apoE and two sialylated apoE isoproteins with approximate molecular weights of 37 kDa (apoEs) and 39 kDa (apoEs2) in brain. These multiple apoE/apoEs/apoEs2band patterns
Externí odkaz:
https://doaj.org/article/720c48fe221140a1b1a7c8646293ffab
Autor:
Julian D. Down, Isabel L. Jackson, Cynthia S. Johnson, Barry P. Katz, Pu Ting Xu, Caroline Hadley, Giao Nguyen, Zeljko Vujaskovic
Publikováno v:
Health Physics. 106:48-55
Approval of radiation countermeasures through the FDA Animal Rule requires pivotal efficacy screening in one or more species that are expected to react with a response similar to humans (21 C.F.R. § 314.610, drugs; § 601.91, biologics). Animal mode
Autor:
Patrick Wincker, Pu-Ting Xu, Sophie Thomas, Michel Vekemans, Marie K Thomas, Arnold Munnich, Marcy C. Speer, Candice Babarit, Heather C. Etchevers, Stanislas Lyonnet
Publikováno v:
Human Molecular Genetics
The fields of both developmental and stem cell biology explore how functionally distinct cell types arise from a self-renewing founder population. Multipotent, proliferative human neural crest cells (hNCC) develop toward the end of the first month of
Autor:
Hong Xu, Christine M. Hulette, Steven R. Gullans, Jonathan L. Haines, Clemens R. Scherzer, Margaret A. Pericak-Vance, Donald E. Schmechel, John R. Gilbert, Yi-Ju Li, Xue Jun Qin, Pu Ting Xu, John F. Ervin
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 2, Pp 256-275 (2006)
Apolipoprotein E4 (APOE4) allele is a major risk factor for late-onset familial and sporadic Alzheimer disease (AD). The mechanism of action of APOE in the etiology of AD remains unclear. Using gene expression (microarray) analysis of human hippocamp
Publikováno v:
Journal of Neuroscience Research. 68:331-336
The apolipoprotein E (apoE) epsilon 4 allele (apoE4) is a major risk factor for neurodegenerative conditions, including Alzheimer's disease (AD). A role for apoE in regeneration of synaptic circuitry after neural injury has been shown in several in v
Publikováno v:
Journal of Neurochemistry. 73:2613-2616
The apolipoprotein E (ApoE) e4 allele is a major risk factor for neurodegenerative conditions, including Alzheimer's disease. A role for ApoE is implicated in regeneration of synaptic circuitry after neural injury. In the in vitro mouse organotypic h
Autor:
Nagesh Rao, Mark J. Pettenati, John R. Gilbert, Pu-Ting Xu, Panayiotis A. Ioannou, Arun Kumar, H. Qiu, D. Lin, S. Newey, Margaret A. Pericak-Vance
Publikováno v:
Human Heredity. 50:151-157
Chromosome 9q34 has been extensively studied and mapped due to the presence of known disease genes, principally tuberous sclerosis 1 (TSC1), in this region. During the course of our mapping of this region we constructed a 555-kb contig beginning appr
Autor:
Allen D. Roses, Donald E. Schmechel, John R. Gilbert, Michael H. Herbstreith, M. E. Eyster, Pu Ting Xu, Tracie Rothrock-Christian, H. Qiu
Publikováno v:
Neurobiology of Disease, Vol 6, Iss 1, Pp 63-75 (1999)
Mice transgenic for human APOE2, E3, and E4 alleles express native 34-kDa human apoE and two sialylated apoE isoproteins with approximate molecular weights of 37 kDa (apoEs) and 39 kDa (apoEs2) in brain. These multiple apoE/apoEs/apoEs2 band patterns
Autor:
Hui Ling Qiu, Donald E. Schmechel, John R. Gilbert, Pu Ting Xu, Tracie R. Rothrock-Christian, Daniel L. Settles, Allen D. Roses
Publikováno v:
Neuroscience Letters. 246:65-68
Apolipoprotein E (APOE, gene; apoE, protein) is a susceptibility gene for late-onset Alzheimer's disease (AD). To examine whether neurons can synthesize apoE, we performed in situ hybridization on brain tissue of transgenic mice carrying genomic cons