Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pu, Fay"'
Autor:
Ruiz-velasco, Andrea, Zi, Min, Hille, Susanne S, Azam, Tayyiba, Kaur, Namrita, Jiang, Juwei, Nguyen, Binh, Sekeres, Karolina, Binder, Pablo, Collins, Lucy, Pu, Fay, Xiao, Han, Guan, Kaomei, Frey, Norbert, Cartwright, Elizabeth J, Müller, Oliver J, Wang, Xin, Liu, Wei
Publikováno v:
Ruiz-velasco, A, Zi, M, Hille, S S, Azam, T, Kaur, N, Jiang, J, Nguyen, B, Sekeres, K, Binder, P, Collins, L, Pu, F, Xiao, H, Guan, K, Frey, N, Cartwright, E J, Müller, O J, Wang, X & Liu, W 2020, ' Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure : javascript:void(0); ', eLife, vol. 9 . https://doi.org/10.7554/eLife.54298, https://doi.org/10.7554/eLife.54298
Myocardial insulin resistance contributes to heart failure in response to pathological stresses, therefore, a therapeutic strategy to maintain cardiac insulin pathways requires further investigation. We demonstrated that insulin receptor substrate 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::873aa4bbef3999b9726ec174eef42bb2
https://elifesciences.org/articles/54298
https://elifesciences.org/articles/54298
Autor:
Binder, Pablo, Wang, Shunyao, Radu, Maria, Zin, Min, Collins, Lucy, Khan, Saba, Li, Yatong, Sekeres, Karolina, Humphreys, Neil, Swanton, Eileithyia, Reid, Adam, Pu, Fay, Oceandy, Delvac, Guan, Kaomei, Hille, Susanne S., Frey, Norbert, Müller, Oliver J., Cartwright, Elizabeth J., Chernoff, Jonathan, Wang, Xin, Liu, Wei
Publikováno v:
Binder, P, Wang, S, Radu, M, Zi, M, Collins, L, Khan, S, Li, Y, Sekeres, K, Humphreys, N E, Swanton, E, Reid, A, Pu, F, Oceandy, D, Guan, K, Hille, S, Frey, N, Müller, O J, Cartwright, E J, Chernoff, J, Liu, W & Wang, X 2019, ' Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response ', Circulation research, vol. 124, no. 5, pp. 696-711 . https://doi.org/10.1161/CIRCRESAHA.118.312829
Circulation Research
Circulation Research
Supplemental Digital Content is available in the text.
Rationale: Secreted and membrane-bound proteins, which account for 1/3 of all proteins, play critical roles in heart health and disease. The endoplasmic reticulum (ER) is the site for synthe
Rationale: Secreted and membrane-bound proteins, which account for 1/3 of all proteins, play critical roles in heart health and disease. The endoplasmic reticulum (ER) is the site for synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::42b2da0ff8f6cfc7ab9af07d921acfab
https://doi.org/10.1161/CIRCRESAHA.118.312829
https://doi.org/10.1161/CIRCRESAHA.118.312829
Autor:
Ruiz-Velasco A; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Zi M; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Hille SS; Department of Internal Medicine III, University of Kiel, Kiel, Germany.; DZHK, German Centre for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Kiel, Germany., Azam T; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Kaur N; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Jiang J; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Nguyen B; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Sekeres K; Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universitaet Dresden, Dresden, Germany., Binder P; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Collins L; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Pu F; Edinburgh University Medical School, Edinburgh, United Kingdom., Xiao H; Institute of Vascular Medicine, Peking University, Beijing, China., Guan K; Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universitaet Dresden, Dresden, Germany., Frey N; Department of Internal Medicine III, University of Kiel, Kiel, Germany.; DZHK, German Centre for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Kiel, Germany., Cartwright EJ; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Müller OJ; Department of Internal Medicine III, University of Kiel, Kiel, Germany.; DZHK, German Centre for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Kiel, Germany., Wang X; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom., Liu W; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, United Kingdom.
Publikováno v:
ELife [Elife] 2020 Mar 30; Vol. 9. Date of Electronic Publication: 2020 Mar 30.
Autor:
Binder P; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Wang S; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Radu M; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA (M.R., J.C.)., Zin M; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Collins L; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Khan S; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Li Y; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Sekeres K; Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universitaet Dresden, Germany (K.S., K.G.)., Humphreys N; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Swanton E; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Reid A; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Pu F; Edinburgh University Medical School, United Kingdom (F.P.)., Oceandy D; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Guan K; Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universitaet Dresden, Germany (K.S., K.G.)., Hille SS; Department of Internal Medicine III, University of Kiel, Germany (S.S.H., N.F., O.J.M.)., Frey N; Department of Internal Medicine III, University of Kiel, Germany (S.S.H., N.F., O.J.M.)., Müller OJ; Department of Internal Medicine III, University of Kiel, Germany (S.S.H., N.F., O.J.M.).; DZHK, German Centre for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Germany (O.J.M.)., Cartwright EJ; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Chernoff J; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA (M.R., J.C.)., Wang X; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.)., Liu W; From the Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom (P.B., S.W., M.Z., L.C., S.K., Y.L., N.H., E.S., A.R., D.O., E.J.C., X.W., W.L.).
Publikováno v:
Circulation research [Circ Res] 2019 Mar; Vol. 124 (5), pp. 696-711.