Zobrazeno 1 - 8
of 8
pro vyhledávání: '"PtdSer, phosphatidylserine"'
Publikováno v:
The Journal of Biological Chemistry
ATP11C is a member of the P4-ATPase flippase family that mediates translocation of phosphatidylserine (PtdSer) across the lipid bilayer. In order to characterize the structure and function of ATP11C in a model natural lipid environment, we revisited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df73493370830dd8a57410478e8a28c0
https://pubmed.ncbi.nlm.nih.gov/34922944
https://pubmed.ncbi.nlm.nih.gov/34922944
Autor:
Jimmy D. Dikeakos, Cassandra R Edgar, Andrés Finzi, S. M. Mansour Haeryfar, Alexa Galbraith, Jérémie Prévost, Mitchell J. Mumby, Rajesh Abraham Jacob, Frank Kirchhoff, Antony Lurie, Steven M. Trothen
Publikováno v:
The Journal of Biological Chemistry
Prolonged immune activation drives the upregulation of multiple checkpoint receptors on the surface of virus-specific T cells, inducing their exhaustion. Reversing HIV-1-induced T cell exhaustion is imperative for efficient virus clearance; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4498fbba12fc0bc9e4265261297f405
http://europepmc.org/articles/PMC8390549
http://europepmc.org/articles/PMC8390549
Autor:
Teddy Ang, Ahrathy Selathurai, Angus Lindsay, Victoria C. Foletta, Gunveen Kaur, Clinton R. Bruce, Sean L. McGee, Micah L Burch, Shaun A. Mason, Steven Hamley, Paul A. Della Gatta, Damien L. Callahan, Grzegorz M Kowalski, Annie R Curtis
Publikováno v:
Molecular Metabolism, Vol 27, Iss, Pp 33-46 (2019)
Molecular Metabolism
Molecular Metabolism
Objective Phosphatidylethanolamine (PtdEtn) is a major phospholipid in mammals. It is synthesized via two pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum and the phosphatidylserine (PtdSer) decarboxylase (PSD) pathway in the mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d48d5b907b2317df0cc50f55e04300
http://www.sciencedirect.com/science/article/pii/S2212877819302698
http://www.sciencedirect.com/science/article/pii/S2212877819302698
Publikováno v:
Fundamental Research
The sudden outbreak of COVID-19 has once again shrouded people in the enormous threat of RNA virus. Extracellular vesicles (EVs), eukaryotic cells-derived small bi-layer vesicles mainly consisting of exosomes and microvesicles, share many properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f206f19d918f7ee813c1621531120b9
http://europepmc.org/articles/PMC7906858
http://europepmc.org/articles/PMC7906858
Autor:
Kai, Chen, Özlem, Günay-Esiyok, Melissa, Klingeberg, Stephan, Marquardt, Thomas Günther, Pomorski, Nishith, Gupta
Publikováno v:
The Journal of Biological Chemistry
Lipid flipping in the membrane bilayers is a widespread eukaryotic phenomenon that is catalyzed by assorted P4-ATPases. Its occurrence, mechanism, and importance in apicomplexan parasites have remained elusive, however. Here we show that Toxoplasma g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::140db4c7d81b20c04f65ef0f673c2898
https://pubmed.ncbi.nlm.nih.gov/33485966
https://pubmed.ncbi.nlm.nih.gov/33485966
Publikováno v:
Biochimica et Biophysica Acta
Prior work has shown that the HIV-1 envelope of the human immunodeficiency virus (HIV) interacts directly with T-cell immunoglobulin mucin (TIM) family proteins. Herein, we demonstrate that HIV-1 envelope glycoproteins from varying HIV-1 clades bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efdb43515f2c0ff15ad58ac3faf7584
https://pubmed.ncbi.nlm.nih.gov/28622976
https://pubmed.ncbi.nlm.nih.gov/28622976
Publikováno v:
ASN Neuro, Vol 1 (2009)
ASN NEURO
ASN NEURO
The mitochondrial lipidome influences ETC (electron transport chain) and cellular bioenergetic efficiency. Brain tumours are largely dependent on glycolysis for energy due to defects in mitochondria and oxidative phosphorylation. In the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f696ce06eaf5b02b2c0a8754e7e140a4
https://doaj.org/article/4a6e8084b4c64a3f9f5c5964b70cf027
https://doaj.org/article/4a6e8084b4c64a3f9f5c5964b70cf027
Autor:
Chen K; Department of Molecular Parasitology, Faculty of Life Sciences, Humboldt University, Berlin, Germany., Huang X; Department of Molecular Parasitology, Faculty of Life Sciences, Humboldt University, Berlin, Germany., Distler U; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany., Tenzer S; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany., Günay-Esiyok Ö; Department of Molecular Parasitology, Faculty of Life Sciences, Humboldt University, Berlin, Germany., Gupta N; Department of Molecular Parasitology, Faculty of Life Sciences, Humboldt University, Berlin, Germany.; Intracellular Parasite Education and Research Labs (iPEARL), Department of Biological Sciences, Birla Institute of Technology and Science, Pilani (BITS-P), Hyderabad, India.
Publikováno v:
Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2023 Feb 18; Vol. 21, pp. 1893-1906. Date of Electronic Publication: 2023 Feb 18 (Print Publication: 2023).