Metabolic model predictions enable targeted microbiome manipulation through precision prebiotics

Autor: Georgios Marinos, Inga K. Hamerich, Reena Debray, Nancy Obeng, Carola Petersen, Jan Taubenheim, Johannes Zimmermann, Dana Blackburn, Buck S. Samuel, Katja Dierking, Andre Franke, Matthias Laudes, Silvio Waschina, Hinrich Schulenburg, Christoph Kaleta

Publikováno v: Microbiology Spectrum, Vol 12, Iss 2 (2024)

ABSTRACTWhile numerous health-beneficial interactions between host and microbiota have been identified, there is still a lack of targeted approaches for modulating these interactions. Thus, we here identify precision prebiotics that specifically modu

Externí odkaz: https://doaj.org/article/dfd5fc11170342dbbd4f161ad4e7fab6

Metabolic model predictions enable targeted microbiome manipulation through precision prebiotics.

Autor: Marinos G; Research Group Medical Systems Biology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Kiel, Schleswig-Holstein, Germany., Hamerich IK; Research Group Evolutionary Ecology and Genetics, Zoological Institute, Kiel University, Kiel, Schleswig-Holstein, Germany., Debray R; Department of Integrative Biology, University of California, Berkeley, California, USA., Obeng N; Research Group Evolutionary Ecology and Genetics, Zoological Institute, Kiel University, Kiel, Schleswig-Holstein, Germany., Petersen C; Research Group Evolutionary Ecology and Genetics, Zoological Institute, Kiel University, Kiel, Schleswig-Holstein, Germany., Taubenheim J; Research Group Medical Systems Biology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Kiel, Schleswig-Holstein, Germany., Zimmermann J; Research Group Medical Systems Biology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Kiel, Schleswig-Holstein, Germany.; Max-Planck Institute for Evolutionary Biology, Ploen, Schleswig-Holstein, Germany., Blackburn D; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA., Samuel BS; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA., Dierking K; Research Group Evolutionary Ecology and Genetics, Zoological Institute, Kiel University, Kiel, Schleswig-Holstein, Germany., Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Schleswig-Holstein, Germany., Laudes M; Institute of Diabetes and Clinical Metabolic Research, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Schleswig-Holstein, Germany., Waschina S; Nutriinformatics, Institute for Human Nutrition and Food Science, Kiel University, Kiel, Schleswig-Holstein, Germany., Schulenburg H; Research Group Evolutionary Ecology and Genetics, Zoological Institute, Kiel University, Kiel, Schleswig-Holstein, Germany.; Max-Planck Institute for Evolutionary Biology, Ploen, Schleswig-Holstein, Germany., Kaleta C; Research Group Medical Systems Biology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Kiel, Schleswig-Holstein, Germany.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 18. Date of Electronic Publication: 2023 Feb 18.