Marginal specificity in protein interactions constrains evolution of a paralogous family.

Autor: Ghose DA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139., Przydzial KE; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139., Mahoney EM; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139., Keating AE; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.; Koch Center for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139., Laub MT; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.; HHMI, Massachusetts Institute of Technology, Cambridge, MA 02139.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 May 02; Vol. 120 (18), pp. e2221163120. Date of Electronic Publication: 2023 Apr 25.