Hydrogen-Deuterium Exchange Mass Spectrometry Identifies Activated Factor IX-Induced molecular Changes in Activated Factor VIII.

Autor: van Galen J; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands., Freato N; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands., Przeradzka MA; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands., Ebberink EHTM; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands., Boon-Spijker M; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands., van der Zwaan C; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands., van den Biggelaar M; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands., Meijer AB; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Thrombosis and haemostasis [Thromb Haemost] 2021 May; Vol. 121 (5), pp. 594-602. Date of Electronic Publication: 2020 Dec 10.

Endocytosis by macrophages: interplay of macrophage scavenger receptor-1 and LDL receptor-related protein-1.

Autor: Béguin EP; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam., Przeradzka MA; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam., Janssen EFJ; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam., Meems H; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam., Sedek M; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam., van der Zwaan C; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam., Mertens K; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam.; Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht., van den Biggelaar M; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Meijer AB; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam s.meijer@sanquin.nl.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Mourik MJ; Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam.

Publikováno v: Haematologica [Haematologica] 2020 Mar; Vol. 105 (3), pp. e133-e137. Date of Electronic Publication: 2019 Jun 27.

The D' domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding.

Autor: Przeradzka MA; Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands., Meems H; Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands., van der Zwaan C; Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands., Ebberink EHTM; Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands., van den Biggelaar M; Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands., Mertens K; Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands., Meijer AB; Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands s.meijer@sanquin.nl.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.

Publikováno v: The Biochemical journal [Biochem J] 2018 Sep 11; Vol. 475 (17), pp. 2819-2830. Date of Electronic Publication: 2018 Sep 11.