Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Przemyslaw Mielczarek"'
Autor:
Anna Bodzon-Kulakowska, Wiesława Młodawska, Przemyslaw Mielczarek, Dorota Lachowicz, Piotr Suder, Marek Smoluch
Publikováno v:
Materials, Vol 16, Iss 4, p 1479 (2023)
Oocytes are a special kind of biological material. Here, the individual variability of a single cell is important. It means that the opportunity to obtain information about the lipid content from the analysis of a single cell is significant. In our s
Externí odkaz:
https://doaj.org/article/5cf075c7a729414482fbaeed4a424670
Autor:
Przemyslaw Mielczarek, Kinga Hartman, Anna Drabik, Hao-Yuan Hung, Eagle Yi-Kung Huang, Ewa Gibula-Tarlowska, Jolanta H. Kotlinska, Jerzy Silberring
Publikováno v:
Molecules, Vol 26, Iss 13, p 3879 (2021)
During the last three decades, a variety of different studies on bioactive peptides that are opioid receptor ligands, have been carried out, with regard to their isolation and identification, as well as their molecular functions in living organisms.
Externí odkaz:
https://doaj.org/article/c27747f40bd74505b8629ca6851746ab
Autor:
Przemyslaw Mielczarek, Tymoteusz Slowik, Jolanta Helena Kotlinska, Piotr Suder, Anna Bodzon-Kulakowska
Publikováno v:
Molecules, Vol 26, Iss 9, p 2737 (2021)
Mass spectrometry imaging is a powerful tool for analyzing the different kinds of molecules in tissue sections, but some substances cannot be measured easily, due to their physicochemical properties. In such cases, chemical derivatization could be ap
Externí odkaz:
https://doaj.org/article/ac28cb9104754ff892ec28eb7fc4e7eb
Publikováno v:
Molecules, Vol 25, Iss 4, p 813 (2020)
This work presents the synthesis of the novel covalent inhibitor of cysteine proteases where epoxide has been replaced by the iodoacetyl functional group. The molecule, similar in action to E-64 and DCG-04, the commonly applied inhibitors, is additio
Externí odkaz:
https://doaj.org/article/2bc11c79103643299a08c80543582079
Autor:
Dorota Lachowicz, Przemyslaw Mielczarek, Roma Wirecka, Katarzyna Berent, Anna Karewicz, Michał Szuwarzyński, Szczepan Zapotoczny
Publikováno v:
Pharmaceutics, Vol 11, Iss 12, p 622 (2019)
A cationic derivative of pullulan was obtained by grafting reaction and used together with dextran sulfate to form polysaccharide-based nanohydrogel cross-linked via electrostatic interactions between polyions. Due to the polycation-polyanion interac
Externí odkaz:
https://doaj.org/article/ee3edf60e2b8426cb3f66f478d1213cb
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 9, Pp 16787-16799 (2014)
The term “cryptome” refers to the subset of cryptic peptides with bioactivities that are often unpredictable and very different from the parent protein. These cryptic peptides are generated by proteolytic cleavage of proteases, whose identificati
Externí odkaz:
https://doaj.org/article/dbea913989954792b66f7fb5bae59fc5
Autor:
Gabriele Antonio Zingale, Francesco Bellia, Ikhlas Mohamed Mohamud Ahmed, Przemyslaw Mielczarek, Jerzy Silberring, Giuseppe Grasso
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4447 (2019)
Insulin-degrading enzyme (IDE) was applied to catalyze hydrolysis of Nociceptin/Orphanin 1-16 (OFQ/N) to show the involvement of the enzyme in degradation of neuropeptides engaged in pain transmission. Moreover, IDE degradative action towards insulin
Externí odkaz:
https://doaj.org/article/4a72ac45922541a6b32f66f452206996
Autor:
Pavel Mucaji, Atanas G. Atanasov, Andrzej Bak, Violetta Kozik, Karolina Sieron, Mark Olsen, Weidong Pan, Yazhou Liu, Shengchao Hu, Junjie Lan, Norbert Haider, Robert Musiol, Jan Vanco, Marc Diederich, Seungwon Ji, Jan Zitko, Dongdong Wang, Danica Agbaba, Katarina Nikolic, Slavica Oljacic, Jelica Vucicevic, Daniela Jezova, Anna Tsantili-Kakoulidou, Fotios Tsopelas, Constantinos Giaginis, Teresa Kowalska, Mieczyslaw Sajewicz, Jerzy Silberring, Przemyslaw Mielczarek, Marek Smoluch, Izabela Jendrzejewska, Jaroslaw Polanski, Josef Jampilek
Publikováno v:
Molecules, Vol 22, Iss 11, p 1848 (2017)
The 46th EuroCongress on Drug Synthesis and Analysis (ECDSA-2017) was arranged within the celebration of the 65th Anniversary of the Faculty of Pharmacy at Comenius University in Bratislava, Slovakia from 5–8 September 2017 to get together speciali
Externí odkaz:
https://doaj.org/article/496ee999e70d45d2bd1f79401d43d3ce
Publikováno v:
Current Issues in Pharmacy and Medical Sciences. 35:11-15
The RF9 compound, which is an antagonist of the FF neuropeptide receptors is used as a therapeutic substance to improve the effectiveness of opioids in the chronic treatment of pain. The purpose of this study was to find the most efficient method of
Publikováno v:
Journal of Mass Spectrometry. 58